Toxicovigilance : A prerequisite to drug safety surveillance in Ayurveda

  • Dr. Smitha Jain Assistant Professor, Dept. of Agada Tantra, Sri Dharmasthala Manjunatheshwara Institute of Ayurveda & Hospital, Bangalore, Karnataka, India.
  • Dr. Reshmi Pushpan Associate Professor, Dept. of Agada Tantra, Sri Dharmasthala Manjunatheshwara Institute of Ayurveda & Hospital, Bangalore, Karnataka, INDIA.
  • Dr. Rashmi BV Assistant Professor, Dept. of Agada Tantra, Sri Dharmasthala Manjunatheshwara Institute of Ayurveda & Hospital, Bangalore, Karnataka, India.
  • Dr. Anitha MG Professor, Dept. of Agada Tantra, Sri Dharmasthala Manjunatheshwara Institute of Ayurveda & Hospital, Bangalore, Karnataka, INDIA.
Keywords: Toxicovigilance, Visha Dravyas, Adverse Drug Reactions

Abstract

Toxicovigilance is the active process of identifying and evaluating the toxic risks existing in a community and evaluating the measures to reduce or eliminate them. Although the technical term “toxicovigilance” does not feature in Ayurvedic texts, its essence is highlighted in Agada Tantra. Agada Tantra has comprehensive approach on toxic effects of Visha Dravyas (toxic substances) and its management. Through toxicovigilance; not merely there is scope for Ayurveda to find solution for toxicity issues, besides there is extensive scope for screening and regulating Ayurvedic formulations containing poisonous drugs of herbal/metal/mineral origin. In fact, study of poisonous drugs and ADR monitoring is an essential aspect in toxicological departments. It is the need of the hour to employ the Ayurvedic discipline of toxicology to explore the challenges that Ayurveda is facing today with regard to drug safety. A comprehensive study of all potential exposure associated with Ayurvedic medicaments, risk assessment, prevention and management can be the primary footstep in this direction. At this point, vigilance of toxic drugs is to be done by considering the guidelines on collection, pharmaceutical processing, indications, contraindications, dosage and antidotes as mentioned in Ayurvedic classics. Thus, data of toxicovigilance can be effectively applied in monitoring drug safety in Ayurveda.

Downloads

Download data is not yet available.

References

Descotes, Jacques & Testud, François. (2005). Toxicovigilance: A new approach for the hazard identification and risk assessment of toxicants in human beings. Toxicology and applied pharmacology. 207. 599-603. 10.1016/j.taap.2005.02.019.

Kushavaha Harischandra Singh. Caraka Samhita (Ayurveda Deepika commentary by Chakrapaani datta). Varanasi: Chowkhamba Choukambha Orientalia, 2011

http://www.cdsco.nic.in/writereaddata/2016Drugs%20 and%20Cosmetics%20Act%201940%20&%20Rules%20 1945.pdf

Government of Indian Ministry of Health and Family Welfare. The Ayurvedic Formulary of India. 2nd ed. New Delhi: National Institute of Science Communication and Information resources; 2003.

Siddhinandan Mishra, Kaviraja Govinda das Sen Bhaishajya ratnavali’ Varanasi: Chaukhambha urabharathi; 2009.

Shastri Kashinath. Rasa tarangini. Reprint.Varanasi: Mothilal Banarasidas; 8th Edition 2014. Parashuram Shastri Vidyasaga; Sharangadharasamhita. Varanasi: Chaukhambha krishnadas Academy 2013

Asha K, Premvati T, Yogaratnakara.1st ed. Varanasi: Chaukhambha Viswabharathi.2010

Siddhinandan Mishra, Rasaratna sammuchaya, 1st edition, Chaukhambha orientalia 2011.

Sharma R, Sharma S. Sahasrayogam. Re Print. Varanasi: Chaukhambha Sanskrit Sansthan; 2012.

Sharma priyawat. Chakradatta. Varanasi: Chaukhambha orientalia; 1994.

Tripati Indradeva, Rasendra Sara Sangraha.2nd ed.Varanasi: Chaukhambha orientalia; 2014

Mahakavi Bhatta shree krishnarampraneeth: Siddha baishajya Mani mala: edited by Sri R Kaladhara Bhatta; 2nd Edition 1999: Krishnadas academy publishers, Varanasi

Shastri Kashinath. Rasa Tarangini. Reprint.Varanasi: Mothilal Banarasidas; 8th Edition 2014.

Murthy KRS. ed., Astanga Hridaya of Vagbhata, Uttarasthana, 6th edition, Varanasi; Chaukhamba Krishnadas academy, 2012

Ashok Kumar Panda, Saroj Kumar Debnath; Overdose effect of aconite containing Ayurvedic Medicine (Mahashankha Vati); International journal of Ayurveda research · July 2010 DOI: 10.4103/0974-7788.72493

CITATION
DOI: 10.21760/jaims.v3i06.549
Published: 2018-12-31
How to Cite
Dr. Smitha Jain, Dr. Reshmi Pushpan, Dr. Rashmi BV, & Dr. Anitha MG. (2018). Toxicovigilance : A prerequisite to drug safety surveillance in Ayurveda. Journal of Ayurveda and Integrated Medical Sciences, 3(06), 144-148. https://doi.org/10.21760/jaims.v3i06.549
Section
Review Article