E-ISSN:2456-3110

Case Report

Diabetic Retinopathy

Journal of Ayurveda and Integrated Medical Sciences

2022 Volume 7 Number 1 Jan-Feb
Publisherwww.maharshicharaka.in

A case study on effect of Vasakadhi Kvatha and Katakadhi Anjana in the management of Diabetic Retinopathy

Vidyasagar Badisa S.1*, Ashwini M.2, Deeksha R.3, Sneha P.4
DOI:

1* S Vidyasagar Badisa, Post Graduate Scholar, Department of Shalakya Tantra, Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Hassan, Karnataka, India.

2 M J Ashwini, Professor, Department of Shalakya Tantra, Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Hassan, Karnataka, India.

3 R Deeksha, Post Graduate Scholar, Department of Shalakya Tantra, Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Hassan, Karnataka, India.

4 P K Sneha, Post Graduate Scholar, Department of Shalakya Tantra, Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Hassan, Karnataka, India.

Background: A known case of diabetic male subject aged 61 years for the past 15 years presented with complaints of blurness of both distant and near vision of both eyes. Methodology: Patient was administered with 50 ml of Vasakadi Kvatha given internally and Katakadhi Anjana drops was administered in each eye twice daily Conclusion: Treatment is done based upon medicines which have Madhumehahara properties, Shothagana properties, Shonita Sthapana, Ropana, Kaphanisaraka, Rakta Prasadana, Sroto Dushti Nirharana, Chaukshya and Balya properties.

Keywords: Diabetic Retinopathy, Katakadhi Anjana, Vasakadhi Kvatha

Corresponding Author How to Cite this Article To Browse
S Vidyasagar Badisa, Post Graduate Scholar, Department of Shalakya Tantra, Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Hassan, Karnataka, India.
Email: 		S Vidyasagar Badisa, M J Ashwini, R Deeksha, P K Sneha, A case study on effect of Vasakadhi Kvatha and Katakadhi Anjana in the management of Diabetic Retinopathy. J Ayu Int Med Sci. 2022;7(1):416-419.
Available From
https://jaims.in/jaims/article/view/1720

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2022-01-27 2022-01-29 2022-02-05 2022-02-12 2022-02-19
Conflict of Interest Funding Ethical Approval Plagiarism X-checker Note
Nil Nil Yes 19%

© 2022by S Vidyasagar Badisa, M J Ashwini, R Deeksha, P K Snehaand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

Journal of Ayurveda and Integrated Medical Sciences 2022;7(1)416
Badisa S. et al: A case study on effect of Vasakadhi Kvatha and Katakadhi Anjana

Introduction

Diabetic Retinopathy (DR) is the most common eye disease occurring in Diabetic patients. It is a common cause of legal blindness in individuals between the age of 20 to 65 years.[1]

It is stated to increase with the projected prevalence of diabetes mellitus predicted to increase to 700 million in 2045.[2]

One-third of an estimated 285 million diabetics are afflicted with vision-threatening DR (VTDR).[3]

Proliferative diabetic retinopathy (PDR) is the most common vision-threatening lesion among type 1 diabetes, and it presents with macular oedema in type-2 diabetes.[4]In Ayurveda, for eye diseases, a few daily regimens like Aschyotana (eye drops), Anjana (Collyrium), Padabhyanga (Foot massage with oil) has been enumerated which are promotive and preventive measures for the Diabetic retinopathy which in turns helps for maintenance of eye health.[5]

Case Report

A male patient of 61 years who was teacher by profession, came with the complaints of blurriness of both distant and near vision since 15years.

History of present illness

Patient was apparently healthy 20 years back. Gradually he developed with blurriness of vision while seeing distant objects since 15 years.

After 1 month he felt difficulty for the near objects also. He consult­ed an ophthalmologist, who prescribed Endo-LASER, and silicone oil implantation, which was done in 2019. He experienced mild clarity of vision after surgery, The same symptoms re­appeared soon, later he consulted for the same complaints and got admitted for further management.

History of past illness

Known case of diabetes mellitus type 2 since 20 years

Under allopathic medication for the same

Treatment history

Endo-laser was done for both eyes in 2019.

Cataract surgery was done for both eyes in 2014.

Examination of the patient


Visual acuity Distant vision without glasses Distant vision with glasses Near vision without glasses Near vision with glasses
Right Eye (OD) 6/12 6/9 N9 N6
Left Eye (OS) 6/12 6/9 N9 N6
Both Eyes (OU) 6/12 6/9 N9 N6

  • In both eyes rubeosis iridis was absent
  • Lens showed pseudophakia with posterior-segment intra-ocular lens (IOL) implantation OU and both direct and consensual pupillary reactions were within normal limits OU.
  • The other structures of anterior segment were within normal limits in both eyes.
  • Poste­rior segment examination showed retinal haemorrhages and hard exudates OU.

Colour Fundal photography

OD

jaims_1720_01.JPG

Vitals

Pulse - 78bpm, regular

BP - 130/90mmhg

Temperature - Afebrile, 98.40 F

Respiratory rate - 18/min


Journal of Ayurveda and Integrated Medical Sciences 2022;7(1)417
Badisa S. et al: A case study on effect of Vasakadhi Kvatha and Katakadhi Anjana

OSjaims_1720_02.JPG

Investigations

On 11-08-2021

FBS - 163.5mg/dl

PPBS - 295.4mg/dl

HbA1C - 9.6%

Treatment given

1. Vasakadhi Kvatha[6] 50ml twice daily 30 mins before food

2. One drop of Katakadhi Anjana[7] was administered in each eye twice daily.

Duration: 60 days

Result

The changes noted after administration of Vasakadhi Kvatha along with Katakadhi Anjana for a period of 60 days is mentioned below

Visual acuity


Visual acuity Distant vision without glasses Distant vision with glasses Near vision without glasses Near vision with glasses
Right Eye (OD) 6/9 6/9 N6 N6
Left Eye (OS) 6/9 6/9 N6 N6
Both Eyes (OU) 6/9 6/9 N6 N6

After treatment

On 11-10-2021

FBS - 124.5mg/dl

PPBS - 225.1mg/dl

HbA1C - 8.5%

Colour fundal photography

ODjaims_1720_03.JPG

OSjaims_1720_04.JPG

Discussion

The ingredients of the Vasakadhi Kwatha not only have effect on eye but also have overall systemic effect like, hypoglycemic, lipid lowering, hypotensive, vasodilator and anti-oxidant properties.[8] Maximum number of drugs were having Tikta-Kashaya Rasa and Laghu- Ruksha Gunas, which acts as Pramehagna, Medohara and Pitta-Rakta Shamana.


Journal of Ayurveda and Integrated Medical Sciences 2022;7(1)418
Badisa S. et al: A case study on effect of Vasakadhi Kvatha and Katakadhi Anjana

In Katakadhi Anjana, Kathaka Phala seeds, Karpoora and Madhu having Vatakaphahara, Chakshushya, Vranashotapachana, Tridoshahara, Mehahara properties and also act as anti- hyperglycemic, antioxidant, anti-inflammatory.[9] Inturn it prevents the oxidative stress damage to the retinal vasculature endothelium.[10]

There is a classical reference Prameha can produce Netra Rogas.[11] After a proper analysis of clinical feature, pathogenesis and stages of DR, the disease can be correlated to Timira with different Doshas predominance in different stages. Vasakadhi Kwatha does Prameha Samprapthi Vigatana, also augments the absorption of intra retinal haemorrhages and exudates.

Reference

  1. Kanski JJ, Clinical Ophthalmology by, Elsevier publication; 6th edition, 2007;Pg566
  2. Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Un­win N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Atlas, 9th edition. Diabetes Research and Clinical Practice 2019; Vol. 157
  3. Yau JW, Rogers SL, Kawasaki R, Lamoreux EL, Kowalski JW, Bek T, et al., Global prevalence and major risk factors of dia­betic retinopathy, Diabetes Care, 2012, Vol. 35, Issue 3, pgs. 556-64
  4. Lee R, Wong TY, Sabanayagam C, Epidemiology of diabetic retinopathy, diabetic macular oedema and related vision loss, Eye and Vision, 2015, Vol. 2, Issue 17, pgs. 1-25
  5. Prashant Nishad: A Conceptual Study on Diabetic Retinopathy and Its Management through Ayurveda; ayurpub; III(6): 1127-1132.
  6. Vr̥nda, Tivārī P. Vr̥ndamādhava, athavā, Siddhayoga. 1st ed. Vārāṇasī: Caukhambhā Viśvabhāratī; 2007.p.62
  7. Śārṅgadhara. Śrīvāstava S. Śārṅgadharasaṃhitā. 8th Vārāṇasī: Caukhambhā Oriyaṇṭāliyā; 1996.p.504
  8. Khan, R., Shamsi, Y. and Nikhat, S., 2020. Medicinal Benefits of Adhatoda Vasica Nees. - In Unani and Contemporary Medicine. CellMed, 10(2), p.3.
  1. Sanmuga Priya E, Venkataraman S. Anti-inflammatory effect of Strychnos potatorum. seeds on acute and subacute inflammation in experimental rat models. Pharmaceutical biology. 2007 Jan 1;45(6):435-9
  2. Abd Rahim. Evaluation of Visual Acuity and Macular Thickness Post Focal Laser with and without Supplementary Honey in Diabetic Macular Oedema (Doctoral Dissertation, Universiti Sains Malaysia
  3. Netraprakashika Edited and translated in Sanskrit by Sharma P.M.D and Varadarajan I.V. New Delhi; CCRAS Publication; 1994.p.76

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