E-ISSN:2456-3110

Review Article

Chandraprabha Vati

Journal of Ayurveda and Integrated Medical Sciences

2022 Volume 7 Number 11 December
Publisherwww.maharshicharaka.in

A Critical Review on Chandraprabha Vati - An Ayurvedic Formulation

Jagani P.1*, Kumar Moharana P.2, Soumya E.3
DOI:

1* Poornasri Jagani, 2nd year PG Scholar, Department of Kayachikitsa, Sri Jayendra Saraswathi Ayurveda College and Hospital, Nazarathpet, Chennai, Tamil Nadu, India.

2 Pradeep Kumar Moharana, Professor, Department of Kayachikitsa, Sri Jayendra Saraswathi Ayurveda College and Hospital, Nazarathpet, Chennai, Tamil Nadu, India.

3 E A Soumya, Assistant Professor, Department of Kayachikitsa, Sri Jayendra Saraswathi Ayurveda College and Hospital, Nazarathpet, Chennai, Tamil Nadu, India.

Herbal and herbo-mineral medicines are been widely used in Ayurveda. It has mentioned indications covering in a broader way. Rasa Oushadhi plays an important role in Ayurveda because of its rejuvenating property along with it provides immunization, long shelf life, and greater efficacy even when given in a low dose. One such classical multi-ingredient herbo- mineral Ayurvedic formulation is Chandraprabha Vati. It has many pharmaco-therapeutical applications. It is formulated with broad spectrum activity and is indicated in various diseases like Prameha, Arbudha, Artava, Mutra Vikaras, Arshas etc. Many formulations are mentioned in the name of Chandraprabha Vati. Chandraprabha Vati is Rasayana, Balya, Tridosha Shamaka properties and also acts as catalyst. It is truly a medicine for all diseases and hence called as Sarvaroga Pranashini and is also been used in ailments of reproductive health in both men and women. Certain researches have been done regarding its hypotensive and hypoglycemic properties. It also provides immunity and strength to the body due to Rasayana. In this study an attempt is made to gather and analyze the formulation having different varieties of Chandraprabha Vati from various classics along with its insight in their ingredients, dosage, indication and mode of action and its applications.

Keywords: Chandraprabha Vati, herbo-mineral, Prameha, Rasayana, Sarva Roga Hara

Corresponding Author How to Cite this Article To Browse
Poornasri Jagani, 2nd year PG Scholar, Department of Kayachikitsa, Sri Jayendra Saraswathi Ayurveda College and Hospital, Nazarathpet, Chennai, Tamil Nadu, India.
Email: 		Poornasri Jagani, Pradeep Kumar Moharana, E A Soumya, A Critical Review on Chandraprabha Vati - An Ayurvedic Formulation. J Ayu Int Med Sci. 2022;7(11):136-144.
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Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2022-11-02 2022-11-04 2022-11-11 2022-11-18 2022-11-25
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© 2022by Poornasri Jagani, Pradeep Kumar Moharana, E A Soumyaand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

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Jagani P et al: A Critical Review on Chandraprabha Vati An Ayurvedic Formulation

Introduction

Ayurveda the epitome of science aims with prevention of diseases and promotion of health. Administration of drugs in compound formulation can enhance the response and were made to improve the palatability. One such formulation is Chandraprabha Vati which comes under Khalveya Rasa and they are combination of herbal and mineral products. Though been a Khalveya Rasa it preserves the properties of herbal components. The word Chandraprabha comes from the word Chandra meaning moon and Prabha means luster, so which gives luster like that of moon is called as Chandraprabha.[1]

Aim and Objectives

1. To put an insight on various references and indications of Chandraprabha Vati

2. To understand the mode of action of Chandraprabha Vati.

Materials and Methods

The material is taken from various texts like Bhaishajya Ratnavali, Sharangdhara Samhita, Yogaratnakara, Rasayogasagara, Rasaratna Samucchaya, Rasendra Sara Sangraha, Bhavaprakasha, Gada Nigraha, Ayurveda Sara Sangraha, Brihat Rasarajasundaram, articles, books etc.

Literature Review

Table 1: Similar references of Chandraprabha Vati in different books

SN Name of the book Same book references
1. Sharangdhara Samhita AFI, Bharat Bhaishajya Ratnakar, Rasa Yogasagara
2. Bhaishajya Ratnavali  -
3. Yogaratnakara Bhaishajya Ratnavali
4. Rasa Ratna Samucchya Bharat Bhaishajya Ratnakar, Rasa Yogasagara
5. Rasendra Sara Sangraha Rasa Yoga Sagara
6. Bhavaprakasha Bharat Bhaishajya Ratnakar, Rasendra Sara Sangraha (Arsha Chikitsa)
7. Gada Nigraha Bharat Bhaishajya Ratnakar
8. Bhrihat Rasaraja Sundara  Rasa Yoga Sagara
9. Bhrihat Rasaraja Sundara  -
10. Ayurveda Sara Sangraha -                       
11. Rasa Yoga Sagara  -

Indications

Chandraprabha Vati is indicated in wide variety of diseases

Table 2: Indications of Chandraprabha Vati

Name of the book Indications
Sharangdhara Samhita[2] 20 types of Prameha, Mutraghata, Mutrakrichra, Ashmari, Vibhanda, Anaha, Shoola, Granthi, Arbuda, Antravridhi, Katishula, Swasa, Kasa, Vicharchika, Andavriddhi, Pandu, Kamala, Halimaka, Kushta, Arshas, Kandu, Pliha, Udara, Bhagandhara, Danta Roga, Netra Roga, Mandagni, Aruchi, Vata Pitta Kapha Vyadhi Hara, Strinaam Artavam Rujam, Pumsam Sukragataan Doshanam
Bhaishajya Ratnavali[3] 20 types of Prameha, 8 types of Mutrakrichra, 4 types of Ashmari, 13 types of Mutraghata, Swasa, Kasa, Antra Vridhi, Pandu, Kamala, Halimaka, Kushta, Mandagni, Aruchi, Vata Pitta Kapha Vyadhi Hara
Yogaratnakara[4] Arshas, Pradara, Jwara, Nadivrana, Ashmari, Vidradi, Agnimandhya, Udara, Pandu, Kamala, Bhagandara, Pitika, Gulma, Prameha, Aruchi, Reto Dosha, Ura-Kshata, Kapha Vata Pitta disorders
Rasaratna Samucchaya[5] Prameha Hara
Rasendra Sara Sangraha[6] Sarva Meha Hara
Bhavaprakasha[7] 6 types of Arshas, Bhagandara, Kamala, Pandu, Mandagni, Nasa Roga, Marmagata vrana, Granthi, Arbudha, Vidradhi, Rajayakshma, Prameha, Yoni Roga, Pradara, Sukra Kshaya, Ashmari, Mutrakrichra, Bahumutrata, Udara, Vata Pitta Kapha Vyadhi Hara
Gada Nigraha[8] 6 types of Arshas, Gulma, Sosha, Kshaya, Kamala, Nadi Dourbalya, Marma Roga, Jalodara, Dirgha Kaleena Jwara, Vidradhi, Yakshma Roga, Bhagandara, Pandu, Granthi, Arbudha, Shlipada, Prameha, Shukra Nasha, Ashmari, Mandagni, Jaravyadhi Nashanam, Kapha Vata Pitta Vyadhi Hara
Brihat Rasaraja Sundaram[9] Pandu, Bhagandara, Mutrakrichra, Prameha, Kshaya, Kasa
Brihat Rasaraja Sundaram[10] Tridoshaja Atisara, Jwara
Ayurveda Sara Sangraha[11] Prameha, Prameha Upadrava, Bahumutrata, Sveta Pradara, Virya Dosha, Mutrakrichra, Mutraghata, Ashmari, Bhagandara, Antra Vriddhi, Pandu, Asrhas, Katishoola,
Rasa Yoga Sagara[12] Shwitra Kushta



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Table 3: Drugs mentioned in Chandraprabha Vati from different authors

Drugs Sh.Sa B. R Y. R R.R. S R.Sa. S Bh. P Ga.Ni B.R.Su B.R.Su Ay.Sa.S R.Yo.Sa
Chandraprabha (Karpura) + + - + + - - - - - -
Vacha + + + - - + + + - + -
Musta + + + - - + + + - + -
Bhunimba + + + - - + + + - + -
Amrita (Guduchi) + - - - - - - + - + -
Devadaru + + + - - + + + - + -
Haridra + + + - - + + + - + -
Ativisha + + + - - + + + - + -
Darvi + + - - - - -   -   -
Pippalimula + + + - - + + + - + -
Chitraka + + + - - + + + - + -
Dhanyaka + + - - - + + + - + -
Amlaki + + + + - + + + - + -
Vibhitaki + + + - - + + + - + -
Haritaki + + + - - + + + - + -
Chavya + + + - - - + - - + -
Vidanga + + - - - + + + - + -
Gajapippali + + - - - + + + - + -
Shunti + + + - - + + + - + -
Maricha + + + - - + + + - + -
Pippali + + + - - + + + - + -
Swarna Makshika + + + - - + + + - + -
Yava Kshara + + + - - + + + - + -
Sarja Kshara + + + - -   - + - + -
Saindhava Lavana + + + - - + + + - + -
Sauvarchala Lavana + + + - - - - + - + -
Vida Lavana + + + - - - - - - + -
Trivrit + + - - - + + - - - -
Danti + + + - - + - + - + -
Patra + + + - - + + + - + -
Twak + + + - - + + - - + -
Ela + + + - + + + + - + -
Vamsalochana + + - - - - + + - + -
Loha Bhasma + + + - + + + + - + -
Sita + + - + + + + + - + -
Shudha Shilajatu + + + - - + + + - + -
Guggulu + + + - - + + + - + -
Kadali - - + - - - - - - - -
Shati (Kachura) - - + - - + + + - + -
Syama - - + - - - - - - - -
Tvakshiri - - + - - - - - - + -
Varana - - + - - - - - - - -
Bola Churna - - - + - - - - - - -
Jatiphala - - - + + - - - - - -
Yashtimadhu - - - + + - - - - - -
Khadira - - - + + - - - - - -
Puga - - - + - - - - - - -
Kasisa - - - + - - - - - - -
Dadima - - - + - - - - - - -
Mudgaparni - - - + - - - - - - -
Mashaparni - - - + - - - - - - -
Dhatura Beeja - - - + - - - - - - -
Amlavetasa - - - + + - - - - - -
Jatikosa - - - - + - - - - - -
Lavanga - - - - + - - - - - -
Madhuka - - - - + - - - - - -
Dhatri - - - - + - - - - - -
Shatapuspa - - - - + - - - - - -
Rasa Sindoora - - - - + - - - - - -
Kantakari - - - - + - - - - - -
Abraka Bhasma - - - - + - - - + - -
Naga Bhasma - - - - + - - - - - -
Vanga Bhasma - - - - + - - - - - -
Jatamansi - - - - - - + - - - -
Daruharidra - - - - - - + + - - -
Amaraharidra - - - - - - + - - - -
Gokshuru - - - - - - - - - + -
Sveta Chandana - - - - - - - - - + -
Big Ela - - - - - - - - - + -
Kabab Chinni - - - - - - - - - + -
Shudha Parada - - - - - - - - + - +
Shudha Gandhaka - - - - - - - - - - +
Bakuchi Beeja Churna - - - - - - - - - - +
Khadira Sara - - - - - - - - + - -
Mocharasa - - - - - - - - + - -
Swarna Bhasma - - - - - - - - + - -

Table 4: Anupana, Bhavana and Prakshepaka Dravyas according to different authors are given below.

Reference Name Prakshepaka Dravya Bhavana Dravya Anupana
Sharangdhara Samhita / AFI Chandraprabha Vati/ Chandraprabha Guggulu Vati - - -
Bhaishajya Ratnavali Chandraprabha Vatika - - -
Yogaratnakar Chandraprabha Gudika - - Takra, Mastu, Go Ghrita, Madhu, Mamsa Rasa
Rasa Ratna Samucchya Chandraprabha Vati - Dadhi, Dugdha, Tumbi Rasa, Laangali Rasa, Mudgaparni Rasa, Mehahara Anupana


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Rasendra Sara Sangraha Chandraprabha Vatika - Laangali Rasa, Mesha Dugdha, Nagavalli Rasa Kashaya prepared with Dhatri, Patola, Guduchi Kashaya and added with 1 Tola of Madhu
Bhavaprakasha Chandraprabha Vati/Gutika - Ghrita Takra, Mastu, Dadhi, Shita Jala
Gada Nigraha Chandraprabha Gutika - - -
Brihat Rasaraja Sundaram Chandraprabha Vati - - Jeeraka
Brihat Rasaraja Sundaram Chandraprabha Vati - - -
Ayurveda Sara Sangraha Chandraprabha Vati - Guduchi Swarasa for 3 days Guduchi Kwatha, Daruharidra Rasa, Bilwapatra Rasa, Gokshura Kwatha, Madhu, Dharoshna Kshira
Rasa Yoga Sagara Chandraprabha Vati -  Gomutra Udumbarika Mula, Jala, Takra

Commonly available formulation of Chandraprabha Vati in market is from Sharangdhara Samhita and Bhaishajya Ratnavali which is also mentioned in AFI. Drugs used in Sharangdhara Samhita are listed below

Table 5

SN Drug name Quantity
1. Chandraprabha (Karpura) 3 gms (1 shana)
2. Vacha 3 gms (1 shana)
3. Musta 3 gms (1 shana)
4. Bhunimba 3 gms (1 shana)
5. Amrita (Guduchi) 3 gms (1 shana)
6. Suradaru 3 gms (1 shana)
7. Haridra 3 gms (1 shana)
8. Ativisha 3 gms (1 shana)
9. Darvi 3 gms (1 shana)
10. Pippalimula 3 gms (1 shana)
11. Chitraka 3 gms (1 shana)
12. Dhyanaka 3 gms (1 shana)
13. Amlaki 3 gms (1 shana)
14. Haritaki 3 gms (1 shana)
15. Vibhitaki 3 gms (1 shana)
16. Chavya 3 gms (1 shana)
17. Vidanga 3 gms (1 shana)
18. Gajapippali 3 gms (1 shana)
19. Shunti 3 gms (1 shana)
20. Maricha 3 gms (1 shana)
21. Pippali 3 gms (1 shana)
22. Makshika 3 gms (1 shana)
23. Sarja Kshara 3 gms (1 shana)
24. Yava Kshara 3 gms (1 shana)
25. Saindhava lavana 3 gms (1 shana)
26. Souvarchala lavana 3 gms (1 shana)
27. Vida lavana 3 gms (1 shana)
28. Trivrit 12 gms (1 karsha)
29. Danti 12 gms (1 karsha)
30.  Patraka 12 gms (1 karsha)
31. Tvak 12 gms (1 karsha)
32. Ela (Sukshma ela) 12 gms (1 karsha)
33. Vamslochana (Vamsa) 12 gms (1 karsha)
34. Loha 24 gms (2karsha)
35. Sita 48 gms (4karsha)
36. Shilajatu 96 gms (8 karsha)
37. Guggulu 96 gms (8 karsha)

Method of preparation according to Sharangdhara Samhita

The Churna Dravyas are powdered and mixed well. In a vessel filled with warm water add Shudha Shilajatu and Shudha Guggulu stir and melt it. After melting keep the vessel from fire and allow it to cool. Then, add all the above powdered drugs with it and make it into a fine bolus. Add rest of Bhasma Dravyas along with Sharkara. With the mixture add little warm water and make a fine mixture. Roll the pills and keep it in shade for drying.

Discussion

Chandraprabha Vati is one of the important formulations used in the classics. It is considered as Sarva Roga Pranaashini which cures all types of diseases. There are various formulations of Chandraprabha Vati in various Samhitas. In this article 11 formulations of Chandraprabha Vati have been discussed. Rasa Yogasagara has mentioned 5 types or varieties of Chandraprabha Vati. Bharat Bhaishajya Ratnakar has mentioned references from various books.[13] In Sharangadhara Samhita 37 ingredients have been mentioned whereas Guduchi is excluded in Bhaishajya Ratnavali. According to Aadamala Chandraprabha is used as Karpura while in Vaidyaka Shabdasindhu Chandraprabha means Kachura or Bakuchi.[14] Others have mentioned Shatavari. Rasendra Sara Sangraha has mentioned two varieties of Chandraprabha Vati one in Prameha Adhikaara and other in Arsha Adhikaara which is similar to Bhavaprakasha in Vatarakta chapter.

Chandraprabha vati has Katu, Tikta, Kashaya and Madhura Rasa, Ushna Virya and Gunas like Laghu, Ushna, Tikshna and Ruksa.



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It acts mainly on urinary and genitary systems. Chandraprabha Vati is mainly indicated in Prameha but according to Rasa Yogasagara 5th formulation it is indicated in Switra Kushta and Bhrihat Rasaraja Sundaram has indicated in Jwara Atisara and Arsha chapters.

According to Dosha - Chandrapabha Vati is mainly Tridoshaja more commonly Vatakapha Shamaka in nature

According to Dhatu - On analyzing the indications and properties this Vati acts on Rasa, Rakta, Mamsa, Medas, Asthi, Majja, Shukra Dhatus

According to Rogamarga

Diseases in Bahya Rogamarga - Vicharchika, Arshas, Shwitra Kushta, Kandu

Diseases in Madhyama Rogamarga - Kati Shula, Mutrakrichra, Mutraghata, Prameha, Pandu, Kamala, Halimaka, Antra Vriddhi

Diseases in Abhyantara Rogamarga - Swasa, Kasa, Arshas, Udara, Jwara, Atisara, Vibandha, Anaha, Pliha Roga, Udara, Aruchi, Agnimandhya

According to Srotas

Pranavaha Srotas - Kasa, Swasa,

Annavaha Srotas - Agnimandhya, Aruchi, Shoola, Anaha

Udakavaha Srotas - Udara, Atisara

Rasavaha Srotas - Jwara, Pandu

Raktavaha Srotas - Kamala, Halimaka, Vicharchika, Shvitra

Mamsa-Medo Vaha Srotas - Prameha

Asthi-Majja Vaha Srotas - Kati Shula

Sukravaha Srotas - Artava Rogas, Pumsatva

Mutravaha Srotas - Mutrakrichra, Mutraghata, Ashmari, Bhagandhara

Purishavaha Srotas - Atisara, Arshas, Vibandha

The drugs like Trivrit, Pippalimoola, Guggulu, Yavakshara relieve anxiety & pain. Drugs having anti-inflammatory properties are Karpoora, Musta, Devadaru, Guggulu, Triphala, Ela, Shilajatu & Makshika Bhasma help in reducing the pain.[15] As it contains Loha Bhasma and Shilajatu it helps in increasing the Bala and reduce fatigue and general debility.

Vitsanga may be considered as Apana Vata Vaigunya and can be understood as constipation. Constipation can also be associated with diverticular disease. Rukshata of Pakwashaya is one of the important causes for Vitsanga and the ingredients of Chandraprabha Vati helps in Apana Anulomana thereby relieving constipation.

In Yakrut Vikara (hepatomegaly), due to Tikta Katu Rasa, Kapha Hara and Mutrala properties of Chandraprabha Vati it helps in reducing the symptoms. In Kumbha Kamala, jaundice patients end up in ascites with portal hypertension. The liver tissues are replaced by scar tissue. So, Chandraprabha Vati possesses properties like Tikta Madhura Rasa, Agni Dipana, Yakrut Vishesha and Rasayana.

In Prameha there will be Mutra Atipravritti and Chala Guna of Vata increases, so Sthira and Sthambana line of treatment should be adopted. Avarna Janya Madumeha mainly vitiates Kapha and Pitta which in turn disrupts Dhatwagni and Jataragni thereby hampering the Dhatus. Chandraprabha Vati due to its Laghu, Ruksha Guna helps in Sodhana of Bahudrava Shleshma and decreases the vitiated Kleda. Shilajatu and Guggulu have properties like Virukshna and Chedaneya which acts on Kapha Dosha and also have Rasayana properties which helps in Madhumeha.

Conclusion

Chandraprabha Vati is a herbo mineral classical formulation having wide range of indications and is efficient mostly in genito-urinary diseases. In clinical practice Chandraprabha Vati of Sharangdhara Samhita is been used widely which is also mentioned in AFI. It has many therapeutic utilities in multi system organ.

Reference

1. Sushanta Kumar Meher, Rabinarayan Acharya, Arun Kumar Das; Review on Pharmaco-therapeutic profile of Chandraprava Vati. Int J Phar Chem. Available from: https://oaji.net/articles/2019/1791-1563793149.pdf

2. Sharangdhara, Gutika kalpana, sharangdhara samhita, translated by Prof.Srikanta murthy, 2nd edition: Chaukambha Orientalia, shloka 40-49.p.105-6


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4. Kumari Asha, Tiwari Premvati, Yogaratnakar, Mehadhikara, 1st ed. Part II, chp.39, Chaukhambha Visvabharati; 2010.p.758-9

5. Vaghattacharya, Rasaratnasamucchaya, edited by Kaviraj Shri Ambikadatta Sashtri, mutrakrichrashmaryadi chiktsanam, ver. 28-29, 8th ed. Chaukhambha Amarbharati Prakashana;1988. p.316

6. Sri Gopalkrishna, Rasendra sarasangraha, Hindi commentary by Vaidya Satyarthprakash, prameha chikitsa, ver.21-25,1st ed. Krishnadas Academy;1994. p. 558-9

7. Bhavamisra, Bhavaprakasa, commentary by Dr. bulusu Sitaram, vataraktaadhikaara, vol.II, chp.29, ver.193-2021st ed. Chaukhambha Orientalia;2010.p.352-3

8. Vaidya Sodhala Sri, Gada Nigraha, Prayoga Khand, hindi commentary by Sri Indradeva Tripathi, Gutikaadhikaaraschaturtha, Chp.4, ver.188-191, 2nd ed. Chaukhambha Sanskrit Sansthan;1991. p. 248-9

9. Chaube Dattaram. P, Apurva rasagrantha, Brihat Rasarajsundaram, arsha rogaadhikara, 3rd ed. Chaukhambha Orientalia; p. 358

10. Chaube Dattaram. P, Apurva rasagrantha, Brihat Rasarajsundaram, jwaratisara adhikara, 3rd ed. Chaukhambha Orientalia; p. 330

11. Pathak ramrakshak Baidya, Ayurveda Sarasangraha, gutika vati prakarana, Baidyanath ayurveda Limited;2008. p. 441-2

12. Haripannaji Pandit Vaidya, Rasayogasagara, vol. I, Varanasi: Chowkhamba Krishnadas Academy;2013. p. 426

13. Shah Nagandas Chhaganlal.Bharat Bhaisajya Ratnakar, Part-II, New Delhi: B. Jain Publishers Pvt. Ltd.; p. 152-55

14. Tripathy Brahmananda, Saranghadhara Samhita with Dipika Hindi Commentry. Varanasi: Chaukhamba Surbharati Prakashan; 2007. Chapter 07 Madhyama Khanda, Vataka Kalpana; p.201-2


15. Kadwalia Geetika, Dr. Sood Prashant and Dr. Guleria Praveen, World Journal of Pharmaceutical Research, Chandraprabha vati in mutrakrichhra - A review, doi :10.20959/wjpr20188-11864


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