Journal of Ayurveda and Integrated Medical Sciences

Yashtimadhu has Madhura Rasa, Guru Snigdha Guna, Sita Virya Madhura Vipaka which makes it Vata Pithahara. As Yastimadhu is Madhura in Rasa and Vipaka it can pacify vitiated Vata directly, because of its Guru Guna it is capable of reducing the Laghu Guna of Vata and Pitta also the Snigdha Guna of the Dravya reduces the Rukshata of Vata. Yashtimadhu Ghrita is anti-inflammatory, antibiotic, antiviral, antioxidant, antiulcer in action. Apart from properties like Daha Samana, Shulahara and Rakta Sthambaka. Yashtimadhu Ghrita is Vrana Ropaka and Shothagna. This only indicates the involvement of Vata and Pitta Dosha in cervical erosion. Yashtimadhu contains glycyrrhizin acid and ammonium salt [GA] which has proven activity of ulcer healing. It contains chemical constituent like glabridin which has the property of anti-oxidant, anti-inflammatory properties. It contains sterols which plays a vital role in cell signalling by helping regulate then process of development. Licochalcone A is a flavonoid found in liquorice root (Glycyrrhiza glabra) having anti-microbial activity. It reduces number of inflammatory cells, and enhanced fibroblasts maturation and tissue alignment and on ulcer healing show increase in the percentage of ulcer contraction and epithelization. As a whole Yastimadhu helped to relief the cervical erosion and symptoms like, Yoni Srava, Yoni Kandu, and Gandha. Nimba Patra Kashaya for Prakshalana, is explained in Gadanigraha under Yonigaadikarana Adhyaya. Nimba is having Tikta and Kashaya Rasa, Kaphahara, Krimighna, Kandughna and Grahi properties. Quercetin and ß-sitosterol were first polyphenolic flavonoids purified from fresh Neem and were known to have antifungal and antibacterial activities. Plants parts shows antimicrobial role through inhibitory effect on microbial growth/potentiality of cell wall breakdown. Nimbidol and edunin are present in leaf which has anti-fungal and anti-microbial property. The Grahi property of Nimba helped in Yoni Srava. Nimbin in neem leaf has the property of anti -pyretic, thus it acted on Yoni Kandu and rashes in the vulva. Nimbidin suppresses the functions of macrophages and neutrophils relevant to inflammation and also

Cervical erosion is the interplay between two epithelia. It is the development of a reddened area on the portio- vaginalis around the external os of the cervix. The squamous covering of the vaginal part of the cervix is replaced by columnar epithelium, which is usually continuous with that lining of the endocervix. Even though there is no direct reference in Ayurveda, the signs and symptoms of cervical erosion can be categorized under Pancha Lakshanas of Vrana. Such as Srava, Akriti, Gandha, Vaivarnya, Vedhana.

In this case study the patient had considerable relief from cervical erosion symptoms of cervical erosion is completely resolved. Yasthimadhu Ghrita Pichu having Madhura Rasa, Vatapittahara, Vrana Shodhana and Vranaropana properties and Nimba Patra Prakshalana which has Tikta and Kashya Rasa, Krimigna and Vrana Ropana properties above said intervention have directly acted on the vaginal mucosa and enabled easier target specific action and helped to reduces number of inflammatory cells, and enhanced fibroblasts maturation and tissue alignment.

On ulcer healing result shows increase in the percentage of ulcer contraction and epithelization. It is also acted on the symptoms i.e., Yoni Srava, Yoni Kandu and Yoni Vedana.

The study may be carried out in large number of subject with longer duration to evaluate and analyse the result.