Journal of Ayurveda and Integrated Medical Sciences

Young onset Parkinson’s disease is a subtype of Parkinson disease occurring at a young age with specific symptoms, genetic correlation and treatment plan. YOPD is a rare genetic Parkinson’s disorder characterized by an age of consent between 21 to 45 prevalence of young onset Parkinson’s disease (YOPD) in Europe is estimated to be 1/5000-8000 (5-10% of all PD patients) male are more affected than females (1.7:1). Women develop the disease 2 year later than men.^[5] The distinction between young onset Parkinson’s disease and late onset Parkinson’s disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (eg., dystonia and levodopa induced dyskinesia’s are more common in YOPD) Young onset Parkinson's disease is characterized by motor symptoms and non-motor symptom. Motor symptoms include tremors, rigidity Bradykinesia and non-motor symptoms psychosis, confusion, hallucination can be present. The early indication of the disorder multiple out searching of bradykinesia such as micrography, mobility problem, decreased facial expression, decreased blinking rate are common in young onset Parkinson disease. In Ayurveda due to similar disease presentation YOPD can be compared with Kampavata. Kampavata has been described the under Vataja Nanatmaja Vikara. The term Kampavata was explained for the first time in the text Basavarajeeyam. Kampavata is a Vata Vyadhi which occurs due to pathological increase of Chala Guna of Vata. Treatment consists of both internal and external administration of different forms aimed to reverse pathology of Vata imbalance.

A 45 year old male patient apparently quite well before 10 years, gradually tremors appear in lower limb after having symptoms he goes under supervision modern allopathic treatment where he diagnosed with YOPD. After taking initial medications such as drugs like tab clonazepam (0.5 mg), tab Pantop (40mg), tab propranolol and Levadopa & carbidopa (110 mg) since 2018. He got temporary relief later on symptoms aggravated and he developed tremors in both upper and lower limbs, disturbed mental condition, slurred speech, constipation, cervical pain and disturbed

YOPD is a neurodegenerative illness. About 10 to 20 percentage of people with PD experience symptoms before age 50 which is called young onset PD. The cause is still unknown exact some factor like genetic factor, environment factor etc. The treatment both PD and YOPD are same but younger people may experiences the disease differently. The progration of the disease in general is slower specially for dyskinesia younger people can take medication other than levodopa. Other medications are MAO-B inhibitor, Amantadin, a dopamine agonists or when tremor is particularly prominent an anticholinergic drug. According to the Ayurveda the disease Kampavata describe under Nanatmaja Vatavyadhi. In Kampavata Avarana of Vata and Dhatukshya are the main pathological manifestation. Acharya Charaka has mentioned Srotoshuddhi, Vatanulomana and Rasayana Chikitsa in management of Avarana. In this disease our intension is given to the treatment with the help of Ayurvedic formulations and Panchakarma therapy in motor and non-motor symptoms and complications of YOPD.

In this study we used Matra Basti of Sahchara Tail. Matrabasti is a type of Sneha Basti in which the Sneha administration is minimal. Basti is administered through Guda which enters in Pakwashaya and pacifies the Vata Dosha in its main Sthana and expels Kapha, Pitta, Mutra and Mala with its potency it reaches all over the