E-ISSN:2456-3110

Research Article

Sthoulya

Journal of Ayurveda and Integrated Medical Sciences

2023 Volume 8 Number 7 July
Publisherwww.maharshicharaka.in

Therapeutic efficacy of Agnimanth.a Patra Swarasa Bhavita Shilajatu in Sthoulya

Reethapriya B.1*, Huddar J.2, Biradar P.3
DOI: http://dx.doi.org/10.21760/jaims.8.7.2

1* B.R Reethapriya, Post Graduate Scholar, Department of Samhita Siddhanta, Dr BNM Rural Ayurvedic Medical College Hospital and P.G Research Center, Vijayapura, Karnataka, India.

2 J.C Huddar, HOD and Professor, Department of Samhita Siddhanta, Dr BNM Rural Ayurvedic Medical College Hospital and P.G Research Center, Vijayapura, Karnataka, India.

3 Pushpa Biradar, Assistant Professor, Department of Samhita Siddhanta, Dr BNM Rural Ayurvedic Medical College Hospital and P.G Research Center, Vijayapura, Karnataka, India.

Sthoulya is burning issue in today’s era. It is defined as condition in which there is excessive amount of Meda in Sphik, Sthana and Udara. Shilajatu and Agnimantha are among the Sthoulyahara drugs which possess Katu, Teekta, Kashaya Rasa, Katu Vipaka, Ushna Veerya. It normalizes the state of Agni, thus regulates Jataragni and checks the excessive growth and accumulation of Meda Dhatu. In present study single group clinical study was done, where 30 patients diagnosed as Sthoulya were randomly selected. They were given the formulation Agnimantha Patra Swarasa Bhavita Shilajatu - B/F for 45 days with Sukoshna Jala as Anupana. The patients were assessed based on special proforma prepared for the study. The data was collected BT, DT and AT and statistically analyzed. Conclusion was thus drawn. There was clinical improvement found in subjective and objective parameters during and after treatment.

Keywords: Sthoulya, Obesity, Meda Dhatu, Agnimantha, Shilajatu

Corresponding Author How to Cite this Article To Browse
B.R Reethapriya, Post Graduate Scholar, Department of Samhita Siddhanta, Dr BNM Rural Ayurvedic Medical College Hospital and P.G Research Center, Vijayapura, Karnataka, India.
Email: 		B.R Reethapriya, J.C Huddar, Pushpa Biradar, Therapeutic efficacy of Agnimanth.a Patra Swarasa Bhavita Shilajatu in Sthoulya. J Ayu Int Med Sci. 2023;8(7):7-10.
Available From
https://jaims.in/jaims/article/view/2596

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2023-05-31 2023-06-02 2023-06-09 2023-06-16 2023-06-23
Conflict of Interest Funding Ethical Approval Plagiarism X-checker Note
Nil Nil Yes 17%

© 2023by B.R Reethapriya, J.C Huddar, Pushpa Biradarand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

Journal of Ayurveda and Integrated Medical Sciences 2023;8(7)7
Reethapriya R et al: Efficacy Agnimanth.a Patra Swarasa Bhavita Shilajatu in Sthoulya

Introduction

Sharira is made up of Sapta Dhatus but Sthoulya persons are nourished excessively by Meda Dhatu and other remaining Dhatus get malnourished. When Kapha Dosha increases in abnormal manner, fat metabolism is hampered and person becomes Sthoola. The fact that Acharyas had a comprehensive idea of the disease is clear from the explanations found.

Obesity is not a single disorder. A variety of methods and criteria are used to diagnose Obesity. It is the quantity of Adipose tissue and not just total body weight that defines Obesity.[1]

Sthoulya is the most common disorder in our society and contribution of modern era. Both Acharya Charaka and Acharya Susruta perceived it as a very serious health problem and hence Acharya Charaka considered it among the Ashta Nindita Purusha and mentions Asta Sthoulya Dosha in the context of Sthoulya.

Acharya Susrutha calls both Sthoulya and Karshya as Rasa Nimittaja, thus highlighting the importance of the type, frequency and amount of food consumed by a person in causing either Sthoulya or Karshya. Acharya Vagbhata is probably the first person to classify Sthoulya as Heena, Madhyama and Ati Sthoulya.[2]

This is very relevant now when contemporary science has proved that the untimely consumption, in large quantity of food rich in fat as the major cause of Obesity especially in growing children. Current world health study claims that obesity is included among the top ten selected risk to health.[3]

Shilajatu amplifies the benefits of other herbs by enhancing their bioavailability. It has Katu, Tikta and Kashaya Rasa, Laghu and Ruksha Guna. It inherently portrays Sheeta Veerya and Katu Vipaka. Being Ruksha and Laghu it pacifies the Kapha and Vata Dosha. So, it normalizes state of Agni thus regulates Jataragni, checks the excessive growth and accumulation of fatty tissues. Agnimantha is having Tikta, Katu and Kashaya Rasa, Laghu and Ruksha Guna, Katu Vipaka, Ushna Veerya, balances Vata and Kapha.[4]

Sthoulya is burning issue in today’s era. So, treatment was aimed towards giving relief to the sufferers and attempt was made to correct the pathology with below mentioned.

Aims and Objectives

To evaluate therapeutic efficacy of Agnimantha Patra Swarasa Bhavita Shilajatu in Sthoulya.

Materials and Methods

Total single group of 30 patients, screened and diagnosed as Sthoulya were registered for the study. Consent was taken towards the willingness of participation in the study.

Inclusion Criteria

1. Patients between 20 to 60 years old were selected.

2. Patients with BMI ranging from 31-35 were selected.[5]

3. Patients with SFT over mid tricep muscle (ranging from 20 mm-24.5mm in Male and 28mm-32.5mm in female) were selected.[6]

Exclusion Criteria: Patients with systemic disorders like uncontrolled Hypertension, Cardiovascular disorders, Endocrine disorders and Pregnancy were excluded from the study.

Assessment Criteria: The effect of formulation was assessed on the basis of the improvement in the following Subjective and Objective criteria.

1. Subjective criteria: Proforma incorporating all clinical aspects mentioned for Sthoulya was prepared. Signs and symptoms of Sthaulya mentioned in Ayurveda and modern science were assigned a suitable scoring pattern to assess the condition of the patients before, during and after treatment.

2. Objective criteria: BMI and SFT were observed before, during and after treatment. Lipid profile was done before and after treatment.

Statistical Analysis: Data was collected before (Day 0), during (Day 23) and after (Day 46). Collected data was analyzed using Paired t test and Friedman test.

Method of preparation of Trial Drug

Agnimantha Patras were washed with clean water and Swarasa was prepared. Shodhita Shilajatu was given Bhavana three times with Agnimantha Patra Swarasa. After proper drying it was finely powdered and filled in 500 mg capsules and stored in hygienic


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Reethapriya R et al: Efficacy Agnimanth.a Patra Swarasa Bhavita Shilajatu in Sthoulya

condition. The prepared capsules were packed within pouch each containing 90 capsules, to fulfill the requirement of 45 days for each patient.

The patients were administered with the prepared capsule internally in the dosage of 500 mg- BD with Sukoshna Jala as Anupana B/F, for 45 days along with specific moderate calorie diet and physical activity (walking).

Then follow up was done during treatment (Day 23) and after 45 days (Day 46) of intervention.

Observations and Results

Observation

In the present study, Maximum patients were in the age group 20-30 years, Maximum patients belonged to Hindu religion, Maximum patients were married, Maximum patients were Literate, Maximum patients were Housewife, Maximum patients were vegetarian, Teekshnagni, Maximum patients had Kulavruttanta, Maximum patients were of Kapha Pittaja Prakruti.

Result

Subjective parameters

Clinical features Mean ±SD Change in % T value P value
BT DT AT BT DT AT
Angachalatva 1.77 1.63 1.07 0.817 0.765 0.691 0.7 3.0609 *0.02807
Weight gain 1.57 0.00 0.00 0.504 0.000 0.000 1.57 60.000 **<0.0001
Swedabadha 1.73 1.47 0.83 0.740 0.681 0.648 0.9 3.0508 *0.02606
Atipipasa 1.20 0.87 0.53 1.031 00.93 0.776 0.67 1.96 0.0695
Dourgandhya 1.63 1.43 0.80 0.615 0.679 0.610 0.83 2.69 *0.0161
Swasakastata 0.77 0.70 0.27 0.728 0.702 0.521 0.5 25.721 **<0.0001
Atikshudha 2.60 2.17 1.43 0.814 0.874 0.774 1.17 44.116 **<0.0001
Dourbalya 2.10 1.63 1.13 0.759 0.718 0.776 0.97 41.518 **<0.0001

Objective parameters

Parameters Mean ±SD Change in % T Value P Value
BT DT AT BT DT AT
BMI 32.25 31.85 31.18 1.417 1.396 1.527 1.07 59.513 **<0.0001
SFT 25.75 24.67 23.38 3.984 4.048 4.072 2.37 58.513 **<0.0001

 

Lipid profile Mean ±SD Change in % T Value P Value
BT AT BT AT
Cholesterol 223.67 212.00 44.602 40.375 11.67 3.907 **<0.001
HDL 64.77 66.87 14.871 14.149 2.1 2.7289 *0.0109
Triglycerides 175.03 155.80 51.297 47.533 19.23 4.034 **<0.001
LDL 112.30 105.47 14.807 13.104 6.83 2.4973 *0.0187
VLDL 31.23 25.30 10.928 9.914 5.93 1.8708 0.0719

** - Highly Significant - <0.001, *- Significant - 0.01 to 0.05, Insignificant - >0.05

Discussion

Sthoulya is the most common disorder in our society and contribution of modern era. Sthoulya is abnormal and excess accumulation of Meda Dhatu in the Spik, Sthana and Udara region which becomes Chala.

Krushya is better than Sthoulya. It does not mean that Obesity cannot be treated or managed. It can be treated but needs a tremendous will power and cooperation from the obese person.

Sthaulya originates due to consumption of Kapha Vriddhikara Ahara, Vihara and Manasa Nidana. These factors derange causing Ama production which results in Medadhatvagni Mandya. This condition leads to excessive growth and accumulation of Meda Dhatu, causing Sthoulya.

Agnimantha processed with Shilajatu is having Katu, Teekta, Kashaya Rasa, Katu Vipaka, Ushna Veerya, Lekhana, Chedana and Rasayana properties which normalize the Agni. Thus regulated Jataragni checks the excessive growth and accumulation of Meda. Agnimantha lowers blood Cholesterol level. Shilajatu contains Fulvic Acid which effectively maintains the optimum energy metabolism and most of the excess calories consumed are burnt off and not converted into fat.

The analyzed data shows that effect of treatment on BMI, SFT, Cholesterol, Triglycerides, Weight gain, Swasakastata, Atikshuda, Dourbalya was Highly Significant.

Effect of treatment on HDL, LDL, Angachalatva, Swedabadha, Dourgandya was found to be Significant.

Effect of treatment on VLDL and Atipipasa was found to be Insignificant.

Reference

1. Bluher M. Adipose tissue dysfunction in Obesity; June 2009, edited by 719.

2. Nishakumari; A textbook of Roganidana and Vikruta Vijnana, Vol 2, Chaukambha Orientalia, Varanasi, 2017.

3. Nishakumari; A textbook of Roganidana and Vikruta Vijnana, Vol 2, Chaukambha Orientalia, Varanasi, 2017.


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4. Brahmashankar Mishra; Bhavaprakasha Samhitha; edited by Brahmashankar Mishra, 7th edition, Chaukambha Sanskrit Sansthana, Varanasi.

5. K. Park, Textbook of Preventive and Social medicine, edited by K.Park, , 16th Edition, published by M/S Banarsidas Bhanot, Jabalpur (India), 2000.

6. Harsha Mohan, Textbook of Pathology, edited by Harsha Mohan, 2nd Edition, published by Jaypee Brothers Medical Publishers (P) Ltd. New Delhi 110002, India.


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