E-ISSN:2456-3110

Research Article

Treatment of Leucorrhoea

Journal of Ayurveda and Integrated Medical Sciences

2024 Volume 9 Number 2 February
Publisherwww.maharshicharaka.in

Comparative study between Patrangasava and Pradararipu Rasa in the treatment of Leucorrhoea

Maiti A1*
DOI:10.21760/jaims.9.2.1

1* Animesh Maiti, Hod Professor, Department of Prasuti Tantra Stri Roga, Belley Sankarpur Rajib Gandhi Memorial Ayurvedic College and Hospital, Belley Sankarpur Kushdanga, West Bengal, India.

Leucorrhoea is a common and significant issue that affects women, particularly during their reproductive years, often experiencing it at least once. It manifests as a discharge of white fluid from the vagina. In this study, we evaluated the comparative efficacy of Patrangasava and Pradararipu Rasa in treating Leucorrhoea. Sixty patients with clinical symptoms including white vaginal discharge, vulva itching, vaginal burning pain, low back pain, and general weakness were selected and divided into two equal groups: Group A and Group B. Group A received treatment with Patrangasava for 3 months, while Group B received treatment with Pradararipu Rasa for the same duration. This prospective, comparative, observational study aimed to assess the effectiveness of these treatments in both groups. The study observed a significant reduction in mean scores of clinical symptoms, particularly white vaginal discharge, in both groups. Overall compliance with the treatment was good in both groups, with a highly significant p-value of < 0.001.

Keywords: Leucorrhoea, Patrangasava, Pradararipu Rasa

Corresponding Author How to Cite this Article To Browse
Animesh Maiti, Hod Professor, Department of Prasuti Tantra Stri Roga, Belley Sankarpur Rajib Gandhi Memorial Ayurvedic College and Hospital, Belley Sankarpur Kushdanga, West Bengal, India.
Email: 		Maiti A, Comparative study between Patrangasava and Pradararipu Rasa in the treatment of Leucorrhoea. J Ayu Int Med Sci. 2024;9(2):1-4.
Available From
https://jaims.in/jaims/article/view/3062

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2023-12-15 2023-12-25 2024-01-05 2024-01-15 2024-01-23
Conflict of Interest Funding Ethical Approval Plagiarism X-checker Note
None declared Nil Yes 18.52

© 2024by Maiti Aand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

J Ayu Int Med Sci 2024;9(2)1
Animesh Maiti. Comparative study between Patrangasava and Pradararipu Rasa

Introduction

Leucorrhoea is a common and major problem in each woman who suffers at least one time specially in her reproductive age. Leucorrhea is a combination of 2 words i.e., Leuco & Rrhoea. Leuco means White and Rrhoea means vaginal discharge. So, leucorrhoea means excessive white vaginal discharge. [1] It is also known as Leukorrhoea or lukoria or likoria or leu.kor.rhea.[2] In this study Gr-A was treated with Patrangasava and Gr-B was treated with Pradararipu Rasa.

Aim and Objectives

To evaluate the role of both drugs that ware Patrangasava and Pradararipu Rasa in the treatment of Leucorrhoea.

Materials and Methods

The study was conducted in the department of Prasuti Tantra and Stri Roga, B.S.R.G.M.A.C & Hospital, West Bengal, in which 60 patients were selected and were divided in two equal groups. 30 patients were taken in Group-A and other 30 Patients were taken in Group-B.

Study design

Prospective and comparative and observative.

Selection criteria

60 female patients were selected with some parameters that were white vaginal discharge, itching of vulva, burning pain in vagina, low back pain and general weakness of women specially during reproductive age.

Exclusion criteria

Patients who were suffering from Cervical Erosion, Genital Prolapse, Pregnancy, CA cervix, Uterine Tumour, positive VDRL, carcinoma, positive pap smear, presence of other infective organism were excluded from the study.

Selection and preparation of the drug

A compound medicine ‘Patrangasava’ has been mentioned in Bhaisajyaratnavali Pradara Roga Chikitsa Prakaranam Adhyaya, was selected for the study in Group-A. The ingredients of the Patrangasava[3] are -

1. Patranga (vakam) - 46 gm

2. Khadirakastha - 46 gm

3. Bark of Adusa plant - 46 gm

4. Flowers of silk cotton tree - 46 gm

5. Root of Bala - 46 gm

6. Purified Bhallatak - 46 gm

7. White and black varieties Sariva - 46 gm

8. Buds of Japakusuma plants - 46 gm

9. Stone of mango - 46 gm

10. Daruharidra - 46 gm

11. Kiratatikta - 46 gm

12. Opium fruits - 46 gm

13. Cumin seed - 46 gm

14. Lauha Bhasma - 46 gm

15. Rasanjana - 46 gm

16. Pulp of unripe Bilwa fruits - 46 gm

17. Bhringaraj - 46 gm

18. Cinnamon bark - 46 gm

19. Saffron - 46

20. Clove - 46 gm

21. Kalka of raisin fruit - 950 gm

22. Powder of Dhataki flowers - 750 gm

23. Water - 25 litres

24. Raw sugar - 4670 gm

25. Honey - 2340 gm

Dissolve all of these drugs into water and add sugar & honey. Put the preparation into an earthen pot coated inside with ghee and fomented. Keep the pot beneath the earth for one month. Remove it thereafter and strain the drug into glass containers.

Another compound medicine Pradararipu Rasa has been mentioned in Bhaisajyaratnavali Pradara Roga Chikitsa Prakaranam Adhyaya was selected for the study in Group-B. The ingredients of the Pradararipu Rasa[4] are -

1. Purified mercury - 1 part

2. Purified sulphur - 1 part

3. Sisak Bhasma - 1 part


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Animesh Maiti. Comparative study between Patrangasava and Pradararipu Rasa

4. Rasanjana - 3 parts

5. Lodhra - 6 parts

6. Decoction or juice of Adusa

First of all, prepare Kajjali out of the mercury and sulphur. Mix rest of the drugs into the Kajjali and process the preparation through a hand mortar along with the decoction or juice of Adusa for one day. Prepare pill measuring 250 mg each. At the end the pills are stored in an air tight container.

Study procedure

Total patients were equally divided in to two groups i.e. Group-A & Group- B.

Group-A - This group was treated with ‘Patrangasava’ - 15 ml with equal quantity of warm water twice daily for 3 months.

Group-B - This group was treated with ‘Pradararipu Rasa’ - 1 pill (250 mg) with honey thrice daily for 3 months.

All groups were similar with regard to the demographic data and baseline parameters. Total score was based on white vaginal discharge, itching of vulva, burning pain in vagina, low back pain and general weakness, in the same parameters.

Observations and Results

Comparative study of the effectiveness between the Group-A and Group-B in same parameters with laboratory investigation before and after treatment (Table no. 1 and 2).

Table 1: Result of the treatment in Group - A

Sign & symptomsMean ± S.Ddf‘t’ valueP valueEffectiveness
BTAT
White vaginal discharge2.35 ± 0.50.60 ± 0.5249.35<0.00187.56
Itching of vulva2.1 ± 0.70.68 ± 0.52411.85<0.00175.00
Burning pain in vagina1.10 ± 0.30.5 ± 0.12142.88<0.0557.06
Low back pain1.33 ± 0.50.45 ± 0.11510.06<0.00162.62
General weakness2.65 ± 0.31.1 ± 0.3146.76<0.00165.00

Table 2: Result of the treatment in Group - B

Sign & SymptomsMean ± S.Ddf‘t’ valueP valueEffectiveness
BTAT
White vaginal discharge2.23 ± 0.50.60 ± 0.5249.12<0.00185.95
Itching of vulva2.2 ± 0.50.40 ± 0.62411.80<0.00177.15
Burning pain in vagina1.19 ± 0.10.33 ± 0.11145.89<0.00168.59
Low back pain1.33 ± 0.40.42 ± 0.121510.01<0.00163.15
General weakness2.55 ± 0.350.46 ± 0.421410.60<0.00164.00

P = <0.001 (Highly Significant)

From the statistical point of view it was observed that out of 30 patients in Group-A,20(66.66 %) patients were cured,6(19.8 %) patients were maximum improved, 3 (9.9 %) patients were moderately improved, 1(3.3%) patients were mildly improved and out of 30 patients in Group-B, 19 (62.7 %) patients were cured,6(19.8%) patients were maximum improved, 3 (9.9%) patients were moderately improved, 2(6.6 %) patients were mildly improved (Table no. 3).

Table 3: Overall clinical assessment of the treatment.

ResultGroup - AGroup - B
No. of pt% of ptNo. of pt% of pt
Cured2066.66 %1962.7 %
Maximum improved619.8 %619.8 %
Moderately improved39.9 %39.9%
Mildly improved13.3 %26.6%

Conclusion

The study observed a highly significant reduction in the mean of white vaginal discharge and significant reduction in the mean of itching of vulva, burning pain in vagina, low back pain and general weakness. The overall compliance to the treatment was excellent in both group and the p value of <0.001 was considered highly significant. Hence, it can be concluded that the both drugs more or less are having same effect. So, we can recommend any one of the drugs for satisfactory management of Leucorrhoea.

References

1. CS DAWN. Textbook of Gynaecology and Contraception. 10th edition. Calcutta: DAWN BOOKS; 1990. p. 487.

2. Merriam-Webster [Internet]. Available from: https://www.merriam-webster.com/dictionary.

3. Shri Gobinda Dasji. Bhaisajya Ratnavali. Vol III. 1st edition. Varanasi: Chaukhambha Sanskrit Bhawan; 2006. Pradara Roga Chikitsa Prakaranam, Chap 66. p. 359.

4. Shri Gobinda Dasji. Bhaisajya Ratnavali. Vol III. 1st edition. Varanasi: Chaukhambha Sanskrit Bhawan; 2006. Pradara Roga Chikitsa Prakaranam, Chap 66. p. 349.


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