A comprehensive review of Formulations containing Mākśika Bhasma

Chandramohan Thirunarayanan; Vairamuthu Kanagaraj

doi:10.21760/jaims.9.9.20

E-ISSN:2456-3110

Review Article

Mākśika Bhasma

Journal of Ayurveda and Integrated Medical Sciences

2024 Volume 9 Number 9 SEPTEMBER

Publisher

www.maharshicharaka.in

A comprehensive review of Formulations containing Mākśika Bhasma

Thirunarayanan C^1*, Kanagaraj V²

DOI:10.21760/jaims.9.9.20

^1* Chandramohan Thirunarayanan, Senior Research Fellow, Ayurveda, National Institute of Indian Medical Heritage Niimh, Hyderabad, Telangana, India.

² Vairamuthu Kanagaraj, Senior Research Fellow, Ayurveda, National Institute of Indian Medical Heritage Niimh, Hyderabad, Telangana, India.

Background: Makshika Bhasma, is a mineral preparation well-known in Rasashastra texts. The Bhasma is prepared by repeatedly exposing selective metallic/mineral origin materials to the incineration method of preparation named Puta.

Aim: To prepare comprehensive data related to various formulations, indications, doses, Anupāna, etc. of Mākśika Bhasma recorded in Bharata Bhaishajya Ratnakara.

Materials and Methods: The data about Mākśika Bhasma from the Bharata Bhaiṣajya Ratnakara is systematically collated and analyzed. Mākśika Bhasma is used as a major and minor ingredient in most formulations, and a different percentage of Mākśika Bhasma is used in various formulations of text. Making a note of this, it has been decided to calculate the percentage of Mākśika Bhasma, Anupana, dose, and therapeutic indications in different formulations.

Results: It is observed that a total of 165 references related to various formulations such as rasa, Vati, Gutika, Leham, Modaka, Avaleha, Loham, and their dosages and indications were observed. Among 14 dosage forms, Rasa was found to be the maximum, followed by Vati, Gutika, Churna, Rasayanam, Lehyam, Loham, Anjana, Guggulu, Kvatha, Modaka, Drava, Pottali, Lepa, and Parpati. It is also found that it is used in various disorders such as Vimśati Prameha, Yakśmā, Grahaṇī, Pāṇḍu, Arsha, Raktapitta, Udara, Netraśukra, Āmavāta, Vātarakta, Mūtrakrchra.

Conclusion: 165 formulations are mentioned in Bharata Bhaishajya Ratnakara, in which Mākśika Bhasma is used as an ingredient Madhu, Ghrita, Ksheera, Pippali, and Guda are found to be the most commonly used Anupana (adjuvant/vehicle). About 65 % of Rasa formulations have Mākśika Bhasma as an ingredient.

Keywords: Mākśika Bhasma, Ayurveda formulation, Bhasma, nanomedicine, Bharata Bhaishjya Ratnakara

Corresponding Author	How to Cite this Article	To Browse
Chandramohan Thirunarayanan, Senior Research Fellow, Ayurveda, National Institute of Indian Medical Heritage Niimh, Hyderabad, Telangana, India. Email:	Thirunarayanan C, Kanagaraj V, A comprehensive review of Formulations containing Mākśika Bhasma. J Ayu Int Med Sci. 2024;9(9):131-146. Available From https://jaims.in/jaims/article/view/3645

Manuscript Received	Review Round 1	Review Round 2	Review Round 3	Accepted
2024-08-12	2024-08-22	2024-09-02	2024-09-12	2024-09-21
Conflict of Interest	Funding	Ethical Approval	Plagiarism X-checker	Note
None	Nil	Yes	13.46

© 2024by Thirunarayanan C, Kanagaraj Vand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

J Ayu Int Med Sci 2024;9(9)131

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Methods Results Discussion Conclusion References

Chandramohan T et al. A comprehensive review of Formulations containing Mākśika Bhasma

Introduction

Mākśika [chalcopyrite (CuFeS2)], one among the Mahārasa is used as a substitute for gold because of their similar therapeutic actions. It is of three types viz., Svarna, Roupya, and Kamsya.^[1] Where Svarna Mākśika type is primarily used for therapeutic purposes and secondarily Roupya type. Rasashastra texts provide information about its characters, properties, pharmacological actions, and therapeutic indications. Mākśika is having Madhura (Svarna Mākśika) and Amla, Kashaya and Madhura (Roupya Mākśika) Rasa; Laghu and Yogavāhi Guna; Sita Virya; Katu Vipaka and does Tridoshaghna, Balya, Rasayana, Pranavardhaka, Vrsya, Caksusya Karma. Chalco pyrite is a compact or micro granular mass with brass-yellow. The person who uses Mākśika internally will not be affected by poison, diseases, or geriatric problems. It is an excellent rejuvenator and aphrodisiac, improves strength, and intellect, and improves the quality of blood. It is indicated in various chronic diseases such as Jvara, Apasmāra, Graha Dosha, Rājayakshma, Pāndu, Prameha, Udara, Kushta, Raktapitta, Gulma, and Netra Rogas.^[2]

Among various forms of medicines, Bhasma attracts because of its unique organometallic preparation involving repeated incineration of various metals or their ores, mixed with a decoction of herbal products, through the process of required Puta which transforms metallic state into its corresponding oxide form. It is often regarded as nanomedicine, symbolizing its size in nanometer range.^[3] Some insights from research on Mākśika Bhasma indicate its use in treating anemia and diabetes. In anemia, Iron and copper are required for hemoglobin synthesis. In the light of haematinic effect, the comparative effect of Bhasmas of Mākśika and Mākśika Satva on the blood profile of rabbits was observed and analysed in a chemical study. It reveals that Mākśika Bhasma was found to be effective in increasing haemoglobin levels.^[4] In a study of the concept of the effect of preparations containing Svarna Mākśika and Virechana Karma over the vitiation of Rakta in Madhumeha, Svarna Mākśika was found effective.^[5] The Physicochemical Study and Quantitative Analysis Swarna Mākśika Bhasma by field emission scanning electron microscopy with energy dispersive x-ray (FESEM-EDX) study enables us to explore major,

minor, and trace elements of swarna Mākśika bhasma after tenth puta are as follows (in mean weight %) Cu (0.337), Fe (54.29), S (0.63), O (27.22), C (2.61), Zi (2.34), Ca (3.16), Si (7.08), Al (0.477), K (1.66), Zn (0.127), Na (0.123), Ni (0.087), Co (0.28) quantitatively.^[6]

The spectrum of Mākśika Bhasma’s utility in cases of cognitive impairment, hepatic dysfunction, leukemia, sex debility, azoospermia, diseases of the eye, and neurological diseases is noteworthy. It is primarily used as a rejuvenator aphrodisiac.^[7] Available Rasashatra Granthas and Chikitsa Granthas provide information about different dosage forms and their usage in different disease conditions, and different contexts. Single-hand information on several pharmacological actions of Mākśika and its Bhasma is still not completely available. This study is, therefore, concentrated on the review work to create an exclusive database on the different formulations containing Mākśika and its Bhasma from the encyclopedia of Ayurvedic formulations - Bharata Bhaishjaya Ratnakara (Five volumes)^[8-12] which is considered as first compilation as per API and it covers almost 9598 formulation or preparation available classical texts of all branches Ayurveda.

Materials and Methods

The information from the encyclopedia of Ayurvedic formulations, Bharata Bhaishjaya Ratnakara was considered for the details on Mākśika and it was collated. Formulations containing Mākśika and its Bhasma as an ingredient were critically studied and recorded systematically including dosage forms. Percentage calculation of Mākśika Bhasma.

Method of calculation is adopted from the published review article titled formulations containing Abraka Bhasma (AB): Percentage of AB = 100 × weight of NB/weight of total solid ingredients (including AB); for example, in Baidhynathrasa (R.R.S 14/49–52), the total weight of all ingredients (mineral and herbal) is 90.003 g, out of which 1.5 g is AB. The percentage of AB is 100 × 1.5 g/90.003 g = 1.66, that is, Go dugdha is not considered for calculation.^[13]

Percentage quantity is determined based on the solid constituents, excluding ingredients like decoctions (Kvatha), fresh juices (Svarasa), ghee (Ghrita), and honey (Madhu).

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Chandramohan T et al. A comprehensive review of Formulations containing Mākśika Bhasma

Results

Bharata Bhaishjaya Ratnakara is a comprehensive source for the compilation of Mākśika Bhasma formulations, which includes 165 references related to various dosages and indications. The most common dosage forms are mentioned in Figure: 1 Rasa was found to be the maximum, followed by Vati, Gutika, Churna, Rasayanam, Lehyam, Loham, Anjana, Guggulu, Kvatha, Modaka, Drava, Pottali, Lepa, and Parpati. 165 numbers of various types of formulations, such as Rasa, Vati, Gutika, Leham, Modak, Avaleha, and Loham formulations, along with indications in different disorders were compiled as shown in Tables 1–5 (formulations containing Mākśika Bhasma as an ingredient along with dose, % of Mākśika, Anupana, and indications). On keen observation, it is noted that Mākśika Bhasma has been used as an ingredient in the formulations. It is also found that it is used in disorders such as Vimśati Prameha, Yakśmā, Grahaṇī, Pāṇḍu, Arsha, Raktapitta, Udara, Netraśukra, Āmavāta, Vātarakta, Mūtrakrchra, etc.,

Discussion

Rasashashtra and Bhaishajya Kalpana is one of the most significant branches of Ayurveda. It involves the selection of genuine raw drugs, their collection, the processing of poisonous herbs, and the manufacture of herbal, herbo-mineral, and herbo-metallic formulations along with their therapeutic indications, dosages, and dietary regimens.Bharata Bhaishajya Ratnakara is a well-known compiled book on 35 different Ayurvedic texts books.

It consists of 9598 formulations, and their description is organized alphabetically.^[16] Formulations containing Mākśika and its Bhasma as an ingredient were critically studied and recorded systematically including dosage forms. Formulations are treated separately when calculating percentages if they contain different Mākśika Bhasma percentages each time they are mentioned.

Bharata Bhaishjaya Ratnakara Part 1
In first part, out of 24 formulations related to Mākśika Bhasma, fifteen are rasa, two are Rasayanam, and one each in Loham, Vati, Gutika, Kvatha, Lehyam, Anjana and Churna references related to Mākśika Bhasma formulation have been mentioned. The highest percentage of Mākśika Bhasma has been mentioned in Amṛtārnava Rasa (1) having 40 % and it is indicated for Vrshyam, Yakśmā, Gara, Arśas, Visha. Ārogyasāgaro Rasa having 38.6 %, used in Pāṇḍu, Aruchi, Guda Roga, Vātavyādhi, Gulma, Śvāsa, Udāvarta. Netraśukra Nashaka Anjanam having 25%, it is used for Netraśukra. Khaṇḍasamam Curnam having 25 % and used in Kuṣṭa, Prameha, Udara, Kāmalā, Halīmaka, Raktapitta, Svayathu. Kusumāyugharasa (Swarna Mākśika & Roupya Mākśika) having 17.8% each Svarna and Roupa Mākśika used for Valipalita Nashanartha, Strishu Samarthyam. The lowest percentage is mentioned for Udarāri Loha - 0.56 % is indicated in Udara, Shotha, Arsha, Pāṇḍu, Kāmalā. In majority of formulations Madhu, Ghrita, Pippali, Ksheeram, Maricha have been mentioned as Anupana. Overall, 9 formulations have been cited as having 1-10% of Maksika Bhasma, 10 having 11-20%, 2 having 21-30%, and 2 having 31-40% as represented in Table 1.

Table 1: List of the formulations containing Mākśika Bhasma (B.B.R. Part 1)

SN	Page No.	Yoga No.	Yoga Name	Yoga Dose	% of Mākśika	Anupana	Indications
1.	77	219	Netraśukra Nashaka Anjanam	-	25	-	Netraśukra
2.	96	272	Agnimukho Rasa	8 Ratti	7.14	Ājyaṃ, Nāgarā, Hingu, Souvarchala, Uṣṇāmbu	Gulma, Śūla
3.	102	288	Anaṅganigoḍa Rasa	1 Masha	2.27	Godugdha, Sita	Vimśati Prameha, Yakśmā, Grahaṇī, Pāṇḍu, Arsha, Raktapitta, Udara.
4.	113	312	Abhrakaharitaki	8 Masha	15.4	Madhu, Ājyaṃ	Tridośaja Arśas
5.	113	315	Amṛtasundaro Rasa	3 Ratti	16.67	-	Vātaja, Kaphaja Rogas
6.	115	320	Amṛtākyaloha Rasāyanam	1-8 Masha	2.55	Mākśika, Sarpi	Raktapitta, Amlapitta, Udara, Grahaṇī, Āmavāta, Vātarakta, Mūtrakrchra, Prameha
7.	127	351	Aṣṭamūrti Rasa	1 Ratti	14.28	-	Bhutajvara, Chaturthaka, Triteeyaka, Dwayahika Jvara
8.	155	449	Ārogyasāgaro Rasa	-	38.6	Maricha, Ājyaṃ	Pāṇḍu, Aruchi, Guda Roga, Vātavyādhi, Gulma, Śvāsa. Udāvarta
9.	159	459	Indrabrahmi Vaṭi	-	12.5	Daśamūla Kashaya, Kana	Apasmāra

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10.	205	636	Kāñcanārādi Kvātha:	-	-	-	Masūrikā
11.	282	944	Kanakasundaro Rasa (2)	1 Masha	3.16	Ardraka Swarasa. Rasona Swarasa	Sannipāta, Kilasa, Sarva Kuṣṭha, Visarpa, Bhagandhara, Jvara, Gara
12.	282	945	Kanakasundaro Rasa (3)	2-3 Ratti	12.12	Madhu, Pippali, Maricha, Ghrita, Ardraka Swarasa, Jayapala Rajah	Balya, Hrdyaṃ, Rasāyanam, Gulma,Śūla
13.	283	946	Kanakasundaro Rasa (4)	1 Gunja	7.14	Ghrita, Madhu, Pippali, Chandana, Takram, Ardraka, Nirgundi, Triphala, Ksheera, Kadaliphala	Jvara, Śiraśūla, Agnimāndhyam, Dhanurvāta, Ekangavāta, Pāṇḍu, KśayaM, Kāsa, Nabhiśūla, Katiśūla
14.	293	974	Kāntarasāyanam	-	8.33	Devadāru Tailam	Dehasiddhi, Vṛśyam, Mangalayam, Dipana, Rasāyanam, Suputreeyam
15.	304	1005	Kāleśvaro Rasa:	1-2 Gunja	1.47	-	Kāsa, Śvāsa, Kapha Roga
16.	311	1028	Kuṣṭhanikṛntano Rasa:	2 Masha	16.67	Bhallātaka, Bakuchi, Pathya, Vidanga, Chitraka, Jeeraka, Badari Moola, Katu Taila, Hingu	Kuṣṭham, Vicarcikā
17.	311	1029	Kuṣṭharudreśvaro Rasa:	1-2 Masha	7.7	Khadira, Asana, Rohitaka Kwatha, Chagamutra	Kuṣṭhaam, Svayathu
18.	322	1061	Khaṇḍasamam Curnam	-	25	Madhu, Mākśika	Kuṣṭhaam, Prameha, Udara, Kāmalā, Halīmaka, Raktapitta, Svayathu
19.	617	8980	Amṛtārnava Rasa (1)	1 Ratti	40	Ghrita, Pippali Churna	Vrshyam, Yakśmā, Gara, Arśas, Visham
20.	618	8982	Amṛteśa Rasa	3 Ratti	16.67	Ashwagandha Churna, Ghrita, Guda, Pippali	Jara
21.	619	8985	Arkeśavara Rasa	4 Ratti	12.5	Kśaudraṃm	Sapta Kuṣṭha, Mandala Kuṣṭha
22.	668	9128	Udarāri Loha	-	0.56	Madhu, Ghrita	Udara, Shotha, Arsha, Pāṇḍu, Kāmalā
23.	781	9525	Kusumāyugharasa (Swarna Mākśika & Roupya Mākśika)	9 Ratti	17.8 Swarna Mākśika, 17.8 Roupya Mākśika	Shalmali Niryasa	Valipalita Nashanartha, Strishu Samarthyam
24.	801	9593	Khecari Guṭikā	Aataki Sama Gutika	16.67	-	Jvara, Gulma, Udara

Bharata Bhaishjaya Ratnakara Part 2

In the second part, out of 22 formulations related to Mākśika, fifteen are rasa, four Vati, three Leham, and two Gutika, one in each Pottali, Rasayanam, and Anjana formulation has been mentioned. The highest percentage of Mākśika Bhasma has been mentioned in Chatusudha Rasa 50 %, Pāṇḍu, Śūla, Gulma, Aṣṭa Mahāgadā. Tamreshvaro Rasaḥ has 30.76 % and is indicated in Kśata Kāsa. Gandhakādipoṭali Rasaḥ has 25 % and it is indicated in Yakrit Roga, Plīha Roga.

Tāpyāyaññjanacatuṣaṭayam 25 % and it is indicated in 4 types of Netraśukra. Candraśekhara Rasa 20 % and it is indicated in Shatarushka, Kuṣṭa. Grahaṇīkapāṭa Rasaḥ 15.62 % and it is indicated in Grahaṇī, Gulma, Kśaya, Kusta, Prameha. The lowest percentage is mentioned in 0.28 % Tālakeśvaro Rasa, it is indicated in Sarva Kuṣṭa. In the majority of the formulations Madhu, Aajyam, Ksheeram, and Ashvangandha have been mentioned as Anupana. Overall, 12 formulations had been cited as having 1-10% of Maksika bhasma, 6 having 11-20%, 2 having 21-30%, 1 having 31-40% and 1 having 50% is represented in Table 2.

Table 2: List of the formulations containing Mākśika Bhasma (B.B.R. Part 2)

SN	Page No.	Yoga No.	Yoga Name	Yoga Dose	% of Mākśika	Anupana	Indications
1.	84	1494	Gaganādi Vaṭi	1 Nishka	14.28	Ghrita, Madhu	Guruvāta, Pitta Roga, Kśaya, Brama, Mada, Shosha, Daha, Trishna
2.	100	1542	Gandhakādipoṭali Rasaḥ	½ Nishaka	25	Ājya, Mākśika, Panchakoola	Yakrit Roga, Plīha Roga
3.	104	1556	Garbhacintāmaṇi Rasaḥ	1 Gunja	11.11	-	Garbini Jvara, Daha, Pradara, Suitka Roga.
4.	118	1596	Grahaṇīkapāṭa Rasaḥ	8 Ratti	15.62	Mākśika	Grahaṇī, Gulma, Kśaya, Kusta, Prameha
5.	123	1607	Grahaṇīgajakesarī Rasaḥ	2 Ratti	1.15	Sunthi, Ghrita	Grahaṇī, Dīpana, Pācana, Ruchikaram, Sarva Atisara
6.	152	1737	Candraprabhā Gutika	-	3.45	-	Arsha, Gulma, Sośa, Kśaya, Kāmalā, Udara, Deergha Jvara, Yakśmā, Bhaganadhara, Pāṇḍu, Arbuda, Granthi, Aśmari, Prameha

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7.	154	1739	Candraprabhā Vati	1-2 Masha	1.07	Ksheera, Disease Specific Kvatha	Sarva Roga, Vimśati Prameha, Mūtrāgāta, Aśmari, Arbuda, Granthi, Andavriddhi, Pāṇḍu, Kāmalā, Halīmaka, Danta Roga, Netra Rogam, Kuṣṭha, Arśas, Vṛśyam, Rasāyanam
8.	205	1884	Chatusudha Rasa	-	50	-	Pāṇḍu, Śūla, Gulma, Aṣṭa Mahāgadā
9.	209	1889	Candraprabhā Rasaḥ	4-6 Ratti	3.44	-	Kshudra Roga, Prameha, Vātavyadhi
10.	211	1895	Candraśekhara Rasa	2 Ratti	20	Nara Mutra	Shatarushka, Kuṣṭhaa
11.	277	2105	Jayamangalo Rasa (3) (Roupya Mākśika)	2 Gunja	2.85	Madhuka Rasa	Visha, Jvara, Achetana, Sannipāta Roga
12.	275	2102	Jantughni Guṭikā	-	13.73	Ashvagandadhi Kvatha	Sarvadeha Roga, Kuṣṭhaa
13.	276	2103	Jayamangalo Rasa (1)	2 Gunja	2.5	Jeeraka, Madhu	Jeerna Jvara, Dhatugata Jvara, Vishama Jvara, Bala-Pushtikara, Sarvaroga
14.	276	2104	Jayamangalo Rasa (2)	-	10	Daśamūla Kashaya	Sannipāta Jvara
15.	278	2108	Jayasundaro Rasa	1 Gunja	1.54	Sita, Ashvagandha, Tamra, Gokshura, Rasottama	Vandhya
16.	289	2131	Jvarakuñjararapārīndra Rasaḥ	4 Gunja	7.27	Parna Kanda	Sarvajvara, Timira, Kāsa, Śvāsa, Prameha, Sotha, Pāṇḍu, Kāmalā, Grahaṇī, Kśaya
17.	390	2528	Tāpyāyaññjanacatuṣaṭayam	-	25	Madhu,	4 Types Of Netraśukra
18.	405	2563	Tāpyādi Rasāyanamm	1 Masura	10	Bringi Rasa	Sakalaamaya
19.	432	2609	Tamreshvaro Rasaḥ	1 Karsha	30.76	Dadima, Triphala, Vyosha, Trayana, Guda.	Kśata Kāsa
20.	449	2652	Tālakeśvaro Rasa	½-1 Karsha	0.28	Mahisha Ājyaṃ, Madhu, Ājyaṃm	Sarva Kuṣṭhaa
21.	470	2688	Tīkśanamukha Rasaḥ(2)	2-3 Ratti	9.09	-	Arśas
22.	471	2690	Tīkśanamukha Rasaḥ(4)	-	11.11	Sita, Madhutrayam	Pitta Arśas

Bharata Bhaishjaya Ratnakara Part 3

In the third part, out of 37 formulations, 25 are Rasa, Seven Vati, one in each Rasayana, Lepa, Parpati, Guggulu, Gutika formulation have been mentioned. The highest percentage of Mākśika Bhasma has been mentioned in Pittaprabhañjano Rasa: having 50 % indicated in Vāta Pitta Rogas. Puṣpadhanvā Rasa:(3) having 40 % indicated for Deerghayu, Stri Roga. Prāṇanātha Rasa:(2) having 26.66 % indicated in Rājayakśmā, Sotha, Udara, Arsha, Grahaṇī, Jvara, Gulma. Niśādivaṭi having 25 % indicated in Kuṣṭha. Pancānana Rasa:(1) having 20.91 %, indicated in Pāṇḍu, Yakśmā,

Halīmakamka Ruja, Kuṣṭha, Grahaṇī, Vātavyadhi, Jvara, Atisara, Śvāsa, Kāsa, Aruchi, Kapha Roga, Gala Roga, Mandagni, Prameha, Gulma. The lowest percentage is mentioned in Nityodaya Rasa: having 1.12 % indicated in Pancha Kāsa, Rājayakśmā, Jeerna Jvara, Aruchi, Visama Jvara, Chaturthaka Jvara, Arsha, Kāmalā, Pāṇḍu, Agnimāndhya, Prameha. In the majority of the formulations Madhu, Ghrita, Dugdha, and Sunthi have been mentioned as Anupana. Out of 37 formulations 17 formulations have been mentioned as having 1-10% of Maksika Bhasma, 15 having 11-20%, 3 having 21-30%, 1 having 31-40%, and 1 formulation having 50% as represented in table 3.

Table 3: List of the formulations containing Mākśika Bhasma (B.B.R. Part 3)

SN	Page No.	Yoga No.	Yoga Name	Yoga Dose	% of Mākśika	Anupana	Indications
1.	110	3207	Divyakhecari Vaṭīkā	1 Ratti	12.5	Bringaraja Swarasa, Madhu, Ājyaṃ,	Ayu, Valipalita, Balyam
2.	111	3208	Divyāmṛta Rasa (1) (Mahakalka)	1 Shana	7.69	-	Rasayan, Śvāsa, Kāsa, Kśaya, Pāṇḍu, Aṣṭa Mahavyadhi, Jara Mrtyu Vivarjit, Jvara
3.	146	3327	Dhātubaddha Rasa	1 Ratti	8.33	-	Sarva Roga
4.	232	3624	Nāga Rāsāyanam	1 Valla	18.18	Madhu, Ājyaṃ	80 Vāta Roga, Dhanurvāta, Kapha Roga, Mutra Roga, Śvāsa, Kāsa, Kśaya, Pāṇḍu, Svayathu, Sheetajvara, Grahaṇī Amadosha, Agni Māndhyam
5.	236	3633	Nāgārjuna Vaṭī	Kola Asthi Pramana	11.11	Guda	Sarva Kuṣṭha, Vicarcikā, Dadru
6.	243	3652	Nārimattagajāṅkuśa Rasaḥ	1 Valla	13.33	-	Prameha, Uru, Stana, Shroni Bala Vridhikara

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7.	245	3655	Nityodaya Rasa:	2 Gunja	1.12	Pippali Churna, Madhu	Pancha Kāsa, Rājayakśmā, Jeerna Jvara, Aruchi, Visama Jvara, Chaturthaka Jvara, Arsha, Kāmalā, Pāṇḍu, Agnimāndhya, Prameha
8.	246	3658	Niśādivaṭi	1 Masha	25	Gomutra	Kuṣṭha
9.	249	3666	Netrāśani Rasa:	1 Masha	16.17	Ghrita, Madhu, Uṣṇāmbu,	Netraroga, Rakta Pitta, Raktasrava, Nakthandhya, Timira, Kacha, Neelika, Patala, Netrarbuda, Adhimantha
10.	387	4166	Patrakādi Lepa:	-	20	-	Sidhma Kuṣṭha, Svitra
11.	413	4270	Pancānana Vaṭi(1)	2 Masha	2.77	Disease Specific Kvatha	Āmavāta, Vātavyādhi,
12.	414	4273	Pancānana Rasa:(1)	1 Ratti	20.91	Pathya, Surana, Sunthi, Ghrita	Pāṇḍu, Yakśmā, Halīmakamka Ruja, Kuṣṭha, Grahaṇī, Vātavyadhi, Jvara, Atisara, Śvāsa, Kāsa, Aruchi, Kapha Roga, Gala Roga, Mandagni, Prameha, Gulma
13.	419	4282	Pancāmṛta Parpaṭi(2)	2 Ratti	1.75	Trikatu,	Kshaya Roga, Svāsa, Kāsa, Visuchika, Prameha, Udara, Aruchi, Chardi, Hridroga, Arshas, Sula, Kustha, Vāta Jvara, Grahani,
14.	428	4295	Pancāmṛta Rasa:(10)	-	16.66	Madhu Sarpi	Jara, Sarva Roga
15.	429	4297	Pancāmṛta Rasa:(12)	1 Ratti- 1masha	20	-	Kśaya, Vātarakta, Svayathu, Sarva Roga, Sarva Śūla, Grahaṇī, Sutika Rogas, Pāṇḍu, Plīha, Unmāda, Prameha, Amlapitta, Atisara, Jvara
16.	430	4298	Pancāmṛta Rasa:(14)	Badara Asthi Pramana	5.813	Maricha	Sarva Roga, Grahaṇī, Kapha Roga, Gulma, Kāsa, Śvāsa
17.	431	4299	Pancāmṛta Loha Guggulu:	1masha	6.32	-	Masthishka Roga, Snayu Roga, Vātavyadhi
18.	432	4302	Pancāsya Rasa:	-	14.28	Madhu	Kāmalā
19.	448	4332	Pāniya Vaṭikā (2) (Siddhaphala0	Tila Pramana	8.33	Sheeta Jala	Tridośaja Jvara, Daha, Kāsa, Śvāsa, Hikka, Aśmari, Vidgraham, Mūtrāgāta,
20.	489	4403	Pittaprabhañjano Rasa:	-	50	Madhu, Ājyaṃ	Vāta Pitta Rogas
21.	491	4407	Pittāntaka Rasa:	2 Gunja	6.25	-	Koshtasritha Pitta, Shakhasritha Pitta, Śūla, Amlapitta, Pāṇḍu, Halīmaka, Arśas,Bhranthi, Vanthi
22.	491	4408	Pittāntaka Rasa:(2)	1 Valla	12.5	Sita, Ksheera, Yashti Kvātha, Sheetambu	Pitta Jvara, Kśaya, Daha, Trishna, Sośa,
23.	492	4409	Pittārśohara Rasa:	1 Masha	11.11	Sita	Arsha
24.	495	4417	Pīyūṣavallī Rasa:	Chanaka Pramana Vati	3.57	Chaga Dugdha, Dugdha, Guda, Vilva	Sarva Atisāra, Grahaṇī, Amapācana, Agni Vridhikara
25.	500	4426	Puṣpadhanvā Rasa:(3)	2 Valla	40	Ghrita, Paya, Madhu	Deerghayu, Stri Roga
26.	503	4432	Pūrṇacandro Rasa:	1 Masha	16.66	Khoudra, Shālmali Pushpa Churna	Durbala, Krisha
27.	512	4452	Prabhakaravati	2 Gunja	20	-	Hridroga
28.	513	4454	Prabhāvati Guṭikā	Kolasthi Pramana	5.88	Uṣṇāmbu	Vāta Roga, Śūla, Kapha Roga, Āma, Grahaṇī, Ajirna
29.	519	4464	Pramehabaddha Rasa	-	7.14	Madhu	Prameha
30.	523	4476	Prāṇanātha Rasa:(1)	1/2 Masha	4	-	Rājayakśmā, Sotha, Udara, Arsha, Grahaṇī, Jvara, Gulma.
31.	524	4477	Prāṇanātha Rasa:(2)	4 Ratti	26.66	-	Rājayakśmā, Sotha, Udara,Arsha, Grahaṇī, Jvara, Gulma.
32.	604	4743	Bāla Rasa:	1 Sarshapa	16.66	-	Sannipāta Jvara, Kāsa, Sarva Roga
33.	607	4754	Bolabaddha Rasa:	Badara Pramana	5.88	-	Kaphaja Kāsa, Śvāsa, Pāṇḍu
34.	663	4935	Bhakttavipāka Vaṭi	Gunja Phala Pramana	4.16	-	Agni Dīpana
35.	668	4947	Bhāskaro Rasa:	1-2 Ratti	16.66	Chitraka Rasa, Ārdraka Rasa	Rājayakśmā, Kaphavāta Roga
36.	676	4962	Bhūdāro Rasa:	8 Gunja	9.09	Kśaudraṃ, Hingu, Sauvarcalā, Sunthi, Uṣṇāmbu	Vāta Śūla
37.	678	4967	Bhairava Rasa	1 Gunja	3.10	Vyosha, Madhu, Guggulu	Kāsa, Śvāsa, Jvara, Gulma, Dushta Kśaya, Prameha, Agnimandhya

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Chandramohan T et al. A comprehensive review of Formulations containing Mākśika Bhasma

Bharata Bhaishjaya Ratnakara Part 4

In the fourth part, out of 48 formulations 26 Rasa, six Vati, one Loham, four each Churna and Gutika, two Avaleha, and one each in Modaka and Rasayana formulations have been mentioned. The highest percentage of Mākśika Bhasma has been mentioned in Vṛddhināśana Rasaḥ - 66.66 % indicated in Āntravriddhi, Maṇḍūrādy Avaleha - 50 % indicated in Pāṇḍu. Mārtāṇḍeśvara Rasaḥ - 47.5 % indicated in Aṣṭamaha Rogas, Śvāsa, Kāsa, Kśaya, Halīmakamka, Pāṇḍu, Jvara, Dīpana, Vandhya.

Mākṣikādi Vaṭi having 33.33 % indicated in Netra Roga. The lowest percentage is mentioned in Vātarāja Vatī (1) 0.56 % used in 80 Vātavyādhi, 40 Pitta Vyādhi, 20 Kaphvyādhi, Śvāsa, Kāsa, Bhagandhara, Urakśata, Śūla, Jvara, Pāṇḍu, Prameha, Raktapitta, Gulma. In the majority of the formulations Madhu, Ghrita, Pippali, Guda have been mentioned as Anupana. Overall, 48 formulations have been mentioned as having 1-10% of Mākśika Bhasma, 13 having 11-20%, 2 having 21-30%, 1 having 31-40%, 2 having 41-50%, and 1 having more than 60 % is represented in table 4.

Table 4: List of the formulations containing Mākśika Bhasma (B.B.R. Part 4)

SN	Page No.	Yoga No.	Yoga Name	Yoga Dose	% of Mākśika	Anupana	Indications
1.	167	5495	Madanasundra Rasaḥ (Swarna & Roupya)(1)	1 Tola	14.28 Each	-	Veerya Vridhi
2.	175	5507	Madhvādi Lehaḥ	5-10 Ratti	20	-	Yakśmā
3.	185	5530	Mahākalkanāmaka Rasaḥ	1 Shana	11.11	-	Bala Vridhi, Sarva Roga, Meha, Arśas, Pāṇḍu, Asa, Śvāsa, Halīmaka , Upadamsa, Phiranga, Kuṣṭha
4.	189	5534	Mahākāmeśvaro Modakaḥ	-	0.37	-	Yakśmā, Pāṇḍu, Arsas, Śvāsa, Halīmaka, Prameha, Unmāda, Jvara, Krimi, Kāmala, Apasmāra
5.	227	5593	Mahodayapratyayasāra Rasaḥ	-	9.25	-	Sarva Roga, Kśaya, Kuṣṭha, Śūla, Adhmana, Vāta And Kapha Rogas
6.	228	5594	Mākṣikādi Cūrṇam	3 Ratti	9.09	Madhu	Shukra Meha
7.	228	5595	Mākṣikādi Vaṭi	2 Ratti	33.33	-	Netra Roga
8.	229	5597	Māṇikyatilaka Rasaḥ	-	10	-	Kuṣṭha
9.	233	5605	Mārtāṇḍeśvara Rasaḥ	-	47.5	Maricha, Ghrita, Ardraka	Aṣṭamaha Rogas, Śvāsa, Kāsa, Kśaya, Halīmakamka, Pāṇḍu, Jvara, Dīpana Vandhya
10.	239	5624	Mūrcachāntaka Rasaḥ	1 Ratti	20	-	Murcha
11.	246	5637	Mṛgāṅka Rasaḥ (Maha) (4)	3 Ratti	20.61	Maricha, Ājyaṃ	Kśaya, Balya, Vṛśyam, Gulma, Vidradi, Murcha, Aṣṭa Mahāgadā, Pāṇḍu, Kāmalā
12.	265	5675	Mehanāśāna Rasaḥ	1-2 Ratti	25	Madhu	Sakala Meha
13.	312	5824	Yakṛtplīhodarāri Loham	3 Ratti	11.11	Parpata Kvatha	Plīha, Yakrt, Śvāsa, Kāsa, Vishama Jvara, Gulma, Sotha, Udara, Anaha, Kāmalā, Pāṇḍu, All Vāta, Pitta, Kapha Rogas
14.	314	5830	Yakṣmāri Lauham	-	20	-	Yakśmā
15.	316	5836	Yogarāja Gutikā(Swarna And Roupya)	Udumbara Sama (1 Tola)	7.35 Each	-	Rasāyanam, Pāṇḍu, Visham, Kāsa, Yakśmā, Vishama Jvara, Kuṣṭha, Meha, Śvāsa, Hikka, Apsamara, Kāmalā
16.	380	6030	RaktapittaNtako Rasaḥ	2 Gunja	14.28	Sita, Kśaudraṃ	Raktapitta, Jvara, Daha, Kśatakśīna, Trishna, Sośa, Arocakā
17.	388	6044	Ratnabhāgottara Rasaḥ	-	8.69	-	Vandhya, Dīpana, Pācana, Vṛśyam, Sarva Garbhini Vyadhi, Pāṇḍu,
18.	431	6118	Rasāmṛt Rasaḥ	1 Karsha	6.66	Payas	Amlapitta, Raktapitta, Sarva Dosha Haram, Jvara.
19.	434	6123	Rasendra Guṭikā (2) (Brihat)	1 Ratti	10.52	-	Kāsa, Kśaya, Śvāsa, Raktapitta, Arocakā, Krimi, Pāṇḍu, Jvara, Amlapittam, Pushtivardhana, Vajeekarana
20.	441	6133	Rājamṛgāṅka Rasa (4)	1 Ratti	3.7	Saindhava, Pipplai Churna, Madhu, Guda, Guduchi Sattva	Sotha, Pāṇḍu, Vātavyādhi, Prameha, Vātarakta, Ādhmana, Aruchi, ApasmāraRa, Halīmaka, Jvara, Dhatu Vardhana
21.	551	6423	Loharasāyanam (2)	-	4.93	Ghrita, Madhu	Rasāyanamm
22.	709	6922	Vaṅgeśvara Rasaḥ (11)	2 Gunja	12.5	-	Prameha, Kśaya, Pancha Kāsa, Aṣṭadasha Kuṣṭha, Pāṇḍu, Halīmaka, Śvāsa, Jvara, Hikka

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Chandramohan T et al. A comprehensive review of Formulations containing Mākśika Bhasma

23.	721	6945	Vaḍavānala Guṭikā	1 Maricha	1.56	Uṣṇāmbu	Śūla, Krimi, Sakala Vaishamya, Grahaṇī, Svayathu, Pāṇḍu Gulma, Arśas, Śvāsa, Kāsa, Jvara
24.	725	6951	Vaḍavānal Rasa (6)	1 Masha	6.66	Ardraka, Pippalimoola Kvatha	Vātavyadhi, Dhanurvāta, Dandavāta, Kampavāta
25.	727	6954	Vaḍavānal Rasa (9)	2 Ratti	16.66	Hingu, Sindhu, Sauvarcalā, Dadima, Vilva, Bringaraja	Sarva Gulma, Parinama Śūla
26.	734	6970	Vasanatatilaka Rasaḥ (2)	3 Ratti	7.14	-	Nanavidha Vayu, ApasmāraRa, Visuchika, Ksaya, Unmāda, Vimśati Prameha
27.	735	6973	Vasantamālinī Rasaḥ (2)	2 Ratti	9.09	Madhu, Pippali, Guduchi Sattva, Matulunga Rasa, Ardraka Rasa	Jeerna Jvara, Dhatugata Jvara, Sarva Prameha, Aśmari
28.	745	6994	Vātarāja Vatī (1)	3 Ratti	0.56	Disease Specific Anupana	80 Vātavyādhi, 40 Pitta Vyādhi, 20 Kaphvyādhi, Śvāsa, Kāsa, Bhagandhara, Urakśata, Śūla, Jvara, Pāṇḍu, Prameha, Raktapitta, Gulma
29.	746	6996	Vātavidhvaṃsana Rasaḥ (1)	2 Ratti	5.55	Maricha, Madhu	Hanustambha, Trikasthamba, Manyāstambha, Jihvasthamba, Adhobaga Vātavyādhi
30.	769	7044	Vidyādhara Rasaḥ	½ Gunja	16.66	Go Dugdha, Gomutra, Kśaudraṃ	Gulma, Plīha
31.	781	7073	Viṣamajvarantaka Loham (1)	-	8.33	-	80 Vātavyādhi, 20 Kaphavyādhi, 7 Kśaya, 18 Kuṣṭha, Agnimāndhya
32.	783	7075	Viṣamajvarantaka Loham (3) (Brihat)	1 Ratti	7.69	Pippali, Guda	Aṣṭa Vidha Jvara, Vishama Jvara
33.	786	7088	Visarpajitḥ	1 Ratti	16.66	-	Visarpa
34.	791	7099	Vṛddhanavāyasa Cūrṇam	6 Ratti	1.515	Kśaudraṃ	Sakala Ruja, Śvāsa, Śūla, Ślīpada, Vidradi, Jatara, Arśas, Pāṇḍu, Gulma, Kāsa, Kśaya, Prameha
35.	792	7100	Vṛddhināśana Rasaḥ	2 Ratti	66.66	-	Āntravriddhi
36.	794	7105	Bṛhatjvaracūḍhāmaṇi Rasa	2 Ratti	7.14	-	Aṣṭavidha Jvara,
37.	798	7111	Bṛhatśayakeśari Rasaḥ (Swarna and Roupya Mākśika)	1 Ratti	4.34	Sita, Pippali, Madhu, Ardraka Svarasa	Ekanaga Vāta, Ekādaśa Roopa Yakśmā, Pāṇḍu, Krimi, Kāsa, Śvāsa, Prameha, Aśmari, Plīha, Gulma, Halīmaka
38.	804	7118	Vetal Rasaḥ	1 Ratti	16.66	-	Jvara
39.	804	7119	Vedavidyā Vaṭī (2)	1 Gunja	5.88	Shalmali Rasa	Madhumeha
40.	808	7130	Vaidyanātha Vaṭī (1)	1 Sarshapa	8.33	Kajjali, Kana,	Sannipāta Jvar, Sotha, Grahaṇī, Pāṇḍu, Shukra, Majjagata Vishama Jvara
41.	222	5583	Mahāsideshvara Rasaḥ	2 Ratti	8.33	Patola, Haridra, Daruharidra, Nimba, Tiktha, Koshataki	Kuṣṭha
42.	452	6156	Rudra Vaṭi	1 Masha	4.54	-	Sarva Kuṣṭha
43.	739	6982	Vātagajāṅkusā Rasaḥ (2)	2 Ratti	7.69	Pippali Kvatha	Gridrasi, Manyāstambha, Urustambha, Hanustambha, Pakshagata, Kroshtukasheersha, Avabahuka
44.	162	5486	Maṇḍūrādy Avaleha	6 Ratti	50	Madhu	Pāṇḍu
45.	166	5494	Madanasandīpana Cuṛṇam	Vidala Pada (1 Tola)	2.77	Sarpi, Madhu	Prameha, Mūtrakrchra, Stridosha, Putra Janayathi, Veerya Heena
46.	194	5540	Mahācandrapabhā Vati	1 Masha	1.96	-	Kśaya, Kuṣṭha, Arśas, Prameha, Udara, Plīha, Agnimadhya, Mūtrāgāta, Visuchika, Galaroga, Karna Roga, Netra Roga, Śiro Roga, Śvāsa, Bhagandhara, Chardi, Bhrama, Pāṇḍu, Halīmaka, Unmāda, Amavāta, Apasmāra, Sthoola
47.	298	5783	Yogottamā Guṭikā	1 Tola	0.59	Madhu	80 Vāta Roga, 40 Pitta Roga, 20 Kapha Roga 8 Types of Udara, 20 Types of Prameha, Svayathu, Vimśati Mūtrakrchra, Nādi Vrana, Aṣṭadasha Kuṣṭha, Kāsa, Śvāsa, Hikka, Hridśūla, Arocakā Gulma, Pāṇḍu, Grahaṇī, Shad Arśas, Arbuda, Gandamāla, Vidradi, Bhagandhara
48.	554	6433	Lohasāra Kalpaḥ	1 Karsha	-	Takra	Grahaṇī, Śūla, Parinamaśūla

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Chandramohan T et al. A comprehensive review of Formulations containing Mākśika Bhasma

Bharata Bhaishjaya Ratnakara Part 5

In the fifth part, out of 34 formulations 27 Rasa, two Loham and one each Anjana, Gutika, Drava, Curna, Guggulu formulations have been mentioned. The highest percentage of Mākśika Bhasma has been mentioned in Svarṇamākśikādi Yoga - 25 % indicated in Netra Śukra. Sudhānidhi Rasaḥ (1) - 25 % indicated in Raktapitta. Sudhānidhi Rasaḥ (5) - 25 % indicated in Raktapitta,

Svaṇemākṣikādi Yogaḥ - 25 % indicated in Rājayakśmā. Śikhivāḍava Rasaḥ - 25 % indicated in Rājayakśmā. The lowest percentage is mentioned in Śūlāntaka Rasaḥ (Swarn&Rajata) having 1.56 % and it is indicated in Koshta Vishuddi, Śūla. In the majority of the formulations Madhu, Ghrita, Dugdha, and Pippali have been mentioned as Anupana. Overall, of 34 formulations 16 formulations have been mentioned as having 1-10% of Mākśika Bhasma, 14 having 11-20%, and 4 having 21-30 % are represented in Table 5.

Table 5: List of the formulations containing Mākśika Bhasma (B.B.R. Part 5)

SN	Page No.	Yoga No.	Yoga Name	Yoga Dose	% of Mākśika	Anupana	Indications
1.	229	7918	Saptavimśatiko Guggulu	2 Masha	1.92	Ghrita, Dugdha, Jala, Kanjika, Mudga, Yusha	Śūla, Kilasa Kuṣṭha, Pāṇḍu, KśayaM, Apasmāra, UnmādaM, Svayathu, Prameha
2.	96	7533	Śaṅkadrāvaḥ	1-2 Ratti	3.7	-	Kāsa Śvāsa, KśayaM,Ajeernam, Grahaṇī, Udaram, Gulmam, Krimi, Arśas, Amavāta, Pāṇḍu, Kuṣṭha, Pakshagata, Aśmari
3.	111	7564	Śaṅkhodara Rasaḥ(4)	1 Gunja	16.66	Kśaudraṃ, Kaṇā, Vilwa, Chaga Paya, Vishwa, Jatiphala, Triphala, Guda, Guggulu, Ajaji, Vijaya	Kāsa, Śvāsa, Kśaya, Ajirna, Jvara, Raktaatisara, Visuchika, Śūla, Arśas, Grahaṇī, Vātavyadhi
4.	121	7587	Śikhivāḍava Rasaḥ	3 Gunja	20	Nagavalli,	Vātagulma,
5.	123	7593	Śilājatu Yogaḥ(2)	6 Ratti	16.66	Ksheera	Kśaya
6.	123	7596	Śilājatu Yogaḥ(5)	-	16.66	Sarpi,	Durbala Deha Dathu
7.	134	7625	Śītajvarahara Rasaḥ	1 Ratti	8.33	-	Shita Jvara,
8.	149	7665	Śūlāntaka Rasaḥ (Swarn&Rajata)	3 Ratti	1.56 Each	Ardraka Swarasa	Koshta Vishuddi, Śūla
9.	162	7691	Śvāsakāleśvara Rasa	1-2 Gunja	4.76	Ardraka Swarasa	Kāsa, Śvāsa, Kśaya, Rājayakśmā
10.	163	7693	Śvāsakāsacintāmaṇi Rasaḥ	2 Ratti	8.69	Pippali, Madhu,	Svasa, Kāsa, Vami, Krimi
11.	297	8109	Sauvīrāñjana(2)	-	14.28	-	Netra Śukra
12.	298	8114	Svarṇamākśikādi Yoga:	-	25	Madhu	Netra Śukra
13.	301	8123	Saṅgrahaṇī Rasaḥ	3 Ratti	9.29	Jaya, Jatiphala, Takra, Paya	Grahani, Kśaya, Gulmam, Śūla, Mahavātavyadhi.
14.	310	8141	SannipātaViddhavaṃsaka	-	5	Daśamūla Kvatha, Arka Kvatha	Sannipāta Roga
15.	312	8145	SannipātaNtaka Rasa (2)	1 Ratti	16.66	Madhu	Sannipāta Roga
16.	313	8148	Saptāmṛta Rasa	Ardha Gunja	14.28	-	Mukha Roga
17.	320	8165	Sarvajvarahara Loham (Brihat)	-	7.69	Pippali, Guda	Veerya Vridhi, Sarva Jvara,
18.	323	8172	Sarvatobhadra Rasaḥ (4)	1 Ratti	10	-	Śūla, Gulma, Jatara, Vātarogam, Peenasa, Jvara, Plīha, Pāṇḍu, KśayaM, Kuṣṭha,, ŚirorogaM
19.	334	8189	Sarvāṅgasundara Rasaḥ (9)	1 Masha	7.69	Vyosha, Sauvarcalā, Hingu, Karanjabeeja, Uṣṇāmbu	Kapha Vāta Rogas, Sarvaśūla

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20.	335	8191	Sarvārogya Rasaḥ	1 Chanaka	6.59	-	Visuchika, Arati, Hikka, Grahaṇī, Sośa, Pāṇḍu, Śūla, Gulma, Śvāsa, Arśas, Vidradi
21.	341	8200	Sarveśvara Rasa (6)	2 Ratti	9.09	-	Sarva Prameha
22.	345	8205	Sarveśvara Loham	2 Ratti	3.57	Madhu	Sarva Rogam, Gulma, Kāmalā, Pāṇḍu, Krimi, Vicarcikā, Amlapitta, Kuṣṭha, Raktapitta
23.	362	8236	Sudhānidhi Rasaḥ (1)	1 Ratti	25	-	Raktapitta
24.	363	8240	Sudhānidhi Rasaḥ (5)	2 Ratti	25	-	Raktapitta
25.	373	8266	Sūtikāntaka Rasa	4 Ratti	12.5	-	Sutika Roga, Grahaṇī, Agnimāndhyam, Atisara, Kāsa, Śvāsa, Vājikarana
26.	377	8276	Sūryakānta Rasa	1 Karsha	14.28	Madhu, Ājyaṃ	Rshyajihvā Kuṣṭhā
27.	380	8280	Sūryaprabhā Guṭikā(2)	1 Tola	6.66	-	Sośa, Kāsa,, Urakśata, Pāṇḍu, Kāmalā, Gulmam, Vidradi, Udara, Parsvaśūla Kśaya, Krimi, Kuṣṭha, Arsha, Grahaṇī, Vishama Jvara
28.	398	8308	SthūlaRājagajakesarī Rasa	2 Ratti	10.71	Pippali, Madhu	Sthūla
29.	401	8315	Svachandanāyaka Rasa	8 Gunja	16.66	-	Vātavyadhi
30.	402	8316	Svacchanda-bhairava Rasa	1 Masha	11.11	Pippali, Sarpi, Kśaudraṃ	Atisara, Agnimadhyam, Āma
31.	414	8345	Svarṇamākṣikādi Cūrṇam	2-3 Ratti	14.28	Ghrita	Balyam
32.	415	8346	Svaṇemākṣikādi Yogaḥ	2 Ratti	25	Ghrita	Rājayakśmā
33.	535	8737	Kṣayakulāntaka Rasaḥ	1 Valla	11.11	Madhu	Jeernajvara, Pāṇḍu, Kāsa, Raktapitta, Tamak Śvāsa, Shandatvam, Vājikaram, Pushti Balya, Rasāyanam,
34.	536	8738	Kṣayakesarī Rasaḥ	-	4.35	Sita, Pippali, Madhu, Ardraka,	Vāta, Pitta, Kapha, Jvara, Sannipāta Jvara, Ekanga Vāta, Sarvangavāta, Ekādaśa Kśaya, Sośa, Pāṇḍu, Krimi, Pancha Kāsa, Śvāsa, Prameha, Udara, Aśmari, Plīha, Gulma, Halīmaka, Balya, Vṛśyam, Rasāyanam, Medhya

Conclusion

There are 165 formulations in Bharata Bhaishjaya Ratnakara containing Mākśika bhasama. Among 14 dosage forms, Rasa was found to be the maximum, followed by Vati, Gutika, Churna, Rasayanam, Lehyam, Loham, Anjana, Guggulu, Kvatha, Modaka, Drava, Pottali, Lepa, and Parpati. Mākśika Bhasma is mostly administered in Rasa form along with a combination of other ingredients. In most cases, Madhu, Ghrita, Ksheera, Pippali, and Guda are found to be the most commonly used Anupana and the dose varies from ½ Ratti to 1 Tola. Bhasama is readily absorbable, adaptable, and assimilated into the body without being toxic when properly prepared. However, more intense studies are needed for a better understanding of the components of Mākśika Bhasma and its effective usage in the prevention and curation of different diseases.

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Review Article

Mākśika Bhasma

Journal of Ayurveda and Integrated Medical Sciences

A comprehensive review of Formulations containing Mākśika Bhasma

Thirunarayanan C1*, Kanagaraj V2

Introduction

Materials and Methods

Results

Discussion

Conclusion

References

Thirunarayanan C^1*, Kanagaraj V²