Putrini
A thin and extensive, studded with serous fluid/pus packets is called Putrini. Bullosis diabeticorum, also known as Bullous disease of diabetes and diabetic bullae, is rare, distinct, spontaneous, non-inflammatory, blistering condition of unknown etiology occurring in the setting of diabetes mellitus. Although bullous disease of diabetes lesions often heal without significant scarring, they may be recurrent and also may lead to ulceration. There have also been reports of osteomyelitis arising at a site of bullous disease of diabetes and reports of amputation due to infection. This can be compared with Putrini.
Masurika
Pimples to the size of lentil seeds are called Masurika. Eruptive xanthomas appear as firm, yellow, waxy pea-like bumps on the skin. The bumps which are surrounded by red halos and are itchy, usually are found on the face and buttocks. This looks like Masurika.
Alaji
A dreadful abscess which is of a red and white colour studded over with blisters or exuding vesicles is called Alaji. Bacterial infections commonly affecting the skin spreads quickly in diabetic individuals. Bacteria viz., Staphylococcus are more common and more serious in people with uncontrolled diabetes. This can be compared with Alaji.
Vidarika
A hard and round abscess as large as a (full-grown) gourd is called Vidarika. Scleroderma diabeticorum, while rare, this skin problem affects people with type 2 diabetes, causing a thickening of the skin on the back of the neck and upper back. This skin lesion looks like the Vidaarikanda.
Vidradhi
An abscess of the Vidradhi type is called Vidradhika. Abscess is a localized collection of pus in the cavity lined by granulation tissue, covered by pyogenic membrane.
Discussion
Dashanga Lepa[7] is a polyherbal formulation consisting of 10 different herbs,
such as, Shirisha (Albizzia lebbeck), Yashtimadhu (Glycyrrhiza glabra), Tagara (Valeriana wallichi), Rakta Chandana (Pterocarpus santalinus), Ela (Elettaria cardomum), Jatamanshi (Nardostachys jatamansi), Haridra (Curcuma longa), Daruharidra (Berberis aristata), Kushta (Saussurea lappa), and Sugandha Bala (Coleus vettiveroides).[8] It is used as a topical treatment in conditions like Visarpa (herpes), Visha Visphota (skin eruptions due to poison) and Dushta Vrana (non-healing wound). This formulation is found to be safe and dermatological manifestations are extremely rare. This article discusses a case of skin rash in a patient with rheumatoid arthritis, on the site of application of Dashanga Lepa. There is a strong association between the event and formulation. This kind of reaction with Dashanga Lepa is rare and unexpected. Recurrence of such a type of reaction is avoidable by properly detecting, evaluating, understanding and reporting such an event. The technique of preparation of the Lepa, which the physician has followed is bit a different from the standard reference. As per classics, all the 10 ingredients need to be powdered and made into a Kalka (semisolid paste) form and during application it is to be mixed with Ghritha (Ghee). Here Ghritha may help in preventing the toxic effects of the formulation and moreover, Ghritha has an antidotal effect in Pitta Prakriti.[9] Many of ingredients of Dashanga Lepa have not been reported for their toxicity. However, Veleriane alkaloid, which is an active chemical constituent of Tagara (Valeriana wallichi) and Jatamansi (Nardostachys jatamansi) has been reported to produce allergic reactions and contact dermatitis.[10] Furthermore, Costus oil (Kushta) has been seen to result in allergic contact dermatitis when used externally.[11] Hence, in this case, we believe that the event may have occurred because of improper selection of the treatment vehicle or sensitivity of some ingredients of the Dashanga Lepa.
Conclusion
Dashanga Lepa is an Ayurvedic Lepa (Semi-strong paste) containing ten substances and carried out topically to treat numerous skin infections along with Visarpa (Herpes), Visha Visphota (pores and skin eruptions due to poison) and Dushta Vrana (non-recovery wound), swellings, boils, migraine, headache, ulcer, pores and skin poisons erysipelas, and many others.