Journal of Ayurveda and Integrated Medical Sciences

2024 Volume 9 Number 12 DECEMBER
Publisherwww.maharshicharaka.in

Bhagandara - A challenge as a Nidanartakara Roga

Patil SA1*
DOI:10.21760/jaims.9.12.33

1* Siddanagouda A Patil, Professor, Department of Shalya Tantra, Ayurveda Mahavidyalaya and Hospital, Hubballi, Karnataka, India.

Bhagandara is one among the Ashtamahagada and which is also considered as graves disease due to its causativity, chronicity and extensively challengeable surgical condition. Bhagandara which can be correlated to Fistula-in-ano of contemporary science opines same in the matter of management. In this case study the Bhagandara can be categorised under aetiology caused due to secondary type i.e., as a Nidanartakara Roga, Vyadhisankara and as Upadrava. Which explains the suitable, timely and effective management of the disease according to its Nidana, Avasta, type and Chikitsa Prayoga. Kshara sutra therapy being one of the promising treatment protocol in management of Bhagandara proves valid in its compelling nature, the same constructiveness has been proven in the present case.

Keywords: Bhagandara, Nidanartakara roga, Vyadhisanakara, Ksharasutra, Fistula-in-ano

Corresponding Author How to Cite this Article To Browse
Siddanagouda A Patil, Professor, Department of Shalya Tantra, Ayurveda Mahavidyalaya and Hospital, Hubballi, Karnataka, India.
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Patil SA, Bhagandara - A challenge as a Nidanartakara Roga. J Ayu Int Med Sci. 2024;9(12):248-253.
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https://jaims.in/jaims/article/view/3862/

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2024-11-08 2024-11-18 2024-11-28 2024-12-09 2024-12-24
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© 2024by Patil SAand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

Download PDFBack To ArticleIntroductionCase StudyResultsDiscussionConclusionReferences

Introduction

Bhagandara is a disease which defines itself as Darana of Bhaga, Guda and Basti Pradesha.[1] Bhagandara is one of graves disease for which Acharya Sushruta and Acharya Vagbhatta in their treatise has considered as one among Ashtamahagada,[2,3] which includes Vatavyadhi, Ashmari, Arsha, Bhagandara, Kushta, Prameha, Muda Garbha and Udara Roga. The word Mahagada indicates disease nature and also prognosis of disease. The disease Bhagandara can be considered as one of Nidanartakara Roga (secondary to other disease), Vyadhisankara (Having other Vyadhi associated with it) and also as a Upadrava.

Bhagandara can be correlated to Fistula-in-ano of conventional system of medicine, where various causative factors have been mentioned which includes non-specific causes like cryptoglandular infection and specific causes like Tuberculosis, ulcerative colitis etc.

One of presentations of extrapulmonary tuberculosis is said to be features of fistula-in-ano. While explaining management of fistula-in-ano which is caused due to tuberculosis, standard protocol says that cause should be treated first followed by treatment of disease to draw betterment of treatment and to avoid recurrence of disease.[4]

With above view Bhagandara can be one of Ubhayartakari type of Nidanartakara Roga as there will be an existence of primary disease even after manifestation of secondary disease[5] Chikitsa for such cases requires Shuddha Chikitsa[6] here management of disease & causative factors are important to suppress chances of reoccurrence of disease. As per all Bhrihatrayees[7,8,9] and other acharyas treatment of Bhagandara is Eshana followed by Bheshaja Prayoga, Agni or Kshara Prayoga and Shastra Prayoga. Kshara Sutra[10] is one of promising treatment modality in disease. Hence in present case study nature of disease and effectiveness of Ksharasutra has been dealt.

Case Study

A 27 years old female patient visited Shalya Tantra OPD, with complaints of Soiling of undergarments, Pain and discomfort while sitting since 1 month, occasionally constipation. Patient has similar complaints since 3 years but occasional in nature.

History of present illness

Patient was apparently normal 3 years back then she gradually developed with abscess at perianal region along with fever, generalized weakness, which used to subside after burst open followed by pus drainage either on its own or on taking conservative medications. The perianal abscess was recurrent in nature. The condition worsened since 1 month hence visited our hospital for further management.

Past medical history

Patient is non diabetic, non-hypertensive and not on any treatment for Thyroid dysfunction. Patient had completed 6 months regimen of anti-tuberculosis treatment for pulmonary Koch’s, which was diagnosed 7 months ago.

Surgical History: Undergone MTP 8 months ago.

Family history: Nothing contributory

Menstrual history: regular, 4-5 days/28 days cycle

Obstetric history: G1 P0 L0 A1

Personal history

  • Appetite - Decreased and mixed type of diet with intake of food at irregular time
  • Bowel - Constipated, regular
  • Micturition - Normal in stream, no urgency/hesitancy/strangury
  • Sleep - Sound
  • Habits - No any habits

General Physical examination

  • Moderately nourished, poorly built with Ectomorph body type
  • Pallor - Absent
  • Icterus - Absent
  • Clubbing - Absent
  • Cyanosis - Absent
  • Lymphadenopathy - Left supraclavicular lymph node and right inguinal lymph node enlargement
  • Oedema - Absent

Systemic examination

  • Central nervous system: Patient was conscious, oriented to time, place and person,

  • and cooperative. All her higher mental functions were normal with normal tendon reflexes.
  • Respiratory system: Normal vesicular breath sounds, Air way entry bilaterally equal, all lungs fields were clear.
  • Cardiovascular system: S1 and S2 heard, no added sounds heard.
  • Gastro intestinal system: Abdomen was soft, non-tender, no distension or organomegaly.

Local Examination: examined on lithotomy position

  • Inspection: External opening was seen at Left anterior of the perianal region approximately at 1 o’ clock position externally, app. 2cm away from the anal verge. Slight seropurulent discharge was seen at external opening.
  • Palpation: Tenderness present at left anterior of the perianal region, Button like nodular swelling was felt at left anterior which was confined to be external opening, on pressing around the opening discharge was present.
  • Digital rectal examination: Sphincter tone was normal, Anterior chronic fissure was felt, internal opening was felt between 12 and 1’o clock position anal mucosa approximately 1.5cm from anal verge, no fresh bleeding or abnormality present.

Lab Investigations

  • Hb - 10.0 g%
  • RBS - 80.9 mg/dl
  • Blood group - ‘O’ Positive
  • Bleeding time - 1 minute 50 seconds
  • Clotting time - 4 minutes 15 seconds
  • Total WBC - 6,500 c/cmm
  • DC - N: 56%, L: 32%, E: 05%, M: 07%, B: 00%
  • ESR - 42 mm at 1st hour
  • HIV 1 & 2 - Negative
  • HBsAg - Negative
  • Chest X-ray - No Significant abnormalities detected.
  • Urine Routine - Micro: NAD, Sugar: NIL, Albumin: NIL

  • Soft tissue USG of left Supraclavicular swelling - Enlarged lymph node likely to be post infective changes.

Diagnosis

Bhagandara - Fistula in ano secondary to Pulmonary Koch’s/extra pulmonary Koch’s

Treatment plan

  • Tracing of Fistula tract f/b Kshara Sutra ligation under Local anesthesia.
  • Bowel regulation using oral laxatives
  • Vrana Ropana Karma
  • Panchavalkala Kwatha for Sitz bath and Jatyadi Taila for Local application
  • Weekly thread changing until the cut through of fistulous tract

Poorva Karma

  • Detailed history was taken, Thorough examination was done, ruled out for Pulmonary and extra pulmonary Koch’s Post Anti-Tubercular regimen
  • Informed consent was taken for the operative procedure.
  • Surgical site preparation done.
  • Tetanus Toxoid 0.5cc given Intramuscularly.
  • Lignocaine 2% plain 0.2cc given Intradermally for sensitivity assessment.
  • Vitals were monitored.
  • Necessary instruments were kept ready for the procedure.

Pradhana Karma

  • Patient was taken on Lithotomy position.
  • Surgical site painted and draped under aseptic measures.
  • Under Local Anesthesia, probing done from left anterior external opening and fistulous tract was traced f/b Kshara sutra ligation done to the traced fistulous tract.
  • Complete hemostasis achieved.
  • Gauze soaked in Jatyadi Taila kept per anum and bandaging done.
  • Patient withstood the procedure well.

Paschat Karma

  • Patient shifted to post operative ward.
  • Vitals were monitored.
  • Taxim 1gm IV infusion was given
  • Inj Dynapar Aq 1cc IM given.

Post operative management

  • Inj Pantop 40 IV OD in the morning
  • Inj Taxim 1g IV Infusion BD
  • Inj Metrogyl 100 ml infusion BD
  • Inj Dynapar Aq IM sos
  • Laxative was given for Bowel regulation
  • Panchavalkala Liquid for Sitz bath thrice a day
  • Jatyadi taila for local application.

Treatment timeline

Time lineTreatment
Operative DayPrimary ligation for fistulous tract
1st sittingKshara sutra Changing
2nd sittingKshara sutra changing
3rd sittingKshara sutra changing
4th sittingCut through of fistulous tract by Agnikarma using Panchalouha Shalaka

During the treatment time line, patient was prescribed with Gandhaka Rasayana tablet, Triphala Guggulu, Laxative for bowel regulation, Panchvalakala Kwatha for sitz bath and Jatyadi Taila for application.

Results

After the completion of treatment patient was called for follow up on 15th day, On evaluation there was no signs of fistula-in-ano or its recurrence, all her symptoms were completely reduced, patient was also feeling better in her general health condition.

Discussion

Bhagandara has been mentioned as one among Mahagada which is difficult to treat. Acharya Sushruta has mentioned 2 types of Sadyasadyta for Bhagandra i.e., Ghora which is Dukha Sadya or Kashta Sadya and Asadya. Vataja, Pittaja, Kaphaja are considered as Kashta Sadya/Dukha Sadya and Sannipataja and Agantuja are considered as Asadya.[11]

According Acharya Charaka treatment for Bhagandara is Eshana followed by Kshara sutra application[8]. Acharya Sushruta has mentioned Bheshaja Prayoga, Agni and Kshara Prayoga and Shastra Chikitsa for Bhagandara[7]. Considering this case as Sannipataja Bhagandara as it involves all the dosha which is said to be Asadya, Although Kshara Karma has been advised in such Asadya type of Bhagandara, where Kshara sutra can be chosen. While explaining the indications of Kshara sutra in Nadivrana Adyaya,[10] Acharya has mentioned application of Kshara Sutra in Krisha, Durbhala, Bheeru, and Nadi present at Marma Sthanas,

Bhagandara which can be correlated to Fistula-in-ano of conventional system of medicine, various etiopathogenesis has explained among that specific cause like tuberculosis has also been included. One of the presentation of extrapulmonary tuberculosis is recurrent fistula in ano. The treatment explained for such type is treating the primary cause and then treating the disease, hence here in the present case the primary cause was treated with Anti-tubercular treatment regimen followed by treatment of fistula in ano. Conventional medicine explains various treatments such as Fistulotomy, Fistulectomy, LIFT, VAAFT procedure, Fistula clip closure etc but the recurrence rates are high.

Here the Bhagandara can be taken as Nidanarthakara Roga - as it is caused secondary to Tuberculosis, where Fistula-in-ano is the extra pulmonary features of Koch’s or one of the causes for Fistula-in-ano is Tuberculosis. As there was presence of both primary and secondary disease when she visited our OPD it can be taken as Ubhayarthakari type of Nidanarthakara Roga, and treatment said for this type is Shuddha Chikitsa that is treating the primary disease followed by treatment of secondary disease, hence the Tuberculosis was treated first by Anti-tubercular treatment followed by treatment of Bhagandara.[4]

This condition can also be taken as Vyadhisankara as there was presentation of both primary and secondary disease. Treatment was done both the Vyadhis. The current presentation of Bhagandara can also be considered as Upadrava, which implies difficulty to treat. Considering all the above conditions Kshara sutra is the suitable and proven treatment for Bhagandara. In this present study the length of tract was approximately 4cm,


patient found relief from the disease within time period of 45days with effective Anushastra and Bheshaja Prayoga.

Conclusion

Acharya Sushruta has mentioned Bhagandara as one of the Ashtamahagada which shows the difficultness in treatment. The disease nature shows the Kashta Sadyata, especially when it is considered as one of the Nidanartakara Vyadhi. Acharya opines that in such Nidanartakara Vyadhi, the Vyadhi which is the Nidana should be treated first then followed by treatment of secondary disease. Here the Bhagandara being the Sannipataja type with involvement of all the dosha along with it being the Nidanartakara Vyadhi, Kshara Karma Prayoga in the form of Kshara Sutra has been adopted. Hence this case study gives us an idea of Nidanartakara Vyadhi as per both ayurveda and conventional system of medicine, about Vyadhisankara and Upadrava and also timely treatment of the disease. Importance of Kshara Sutra Prayoga in Bhagandara and the meticulousness has been highlighted.

jaims_3862_01.JPG
Figure 1: Before treatment

jaims_3862_02.JPG
Figure 2: Durning the treatment

jaims_3862_03.JPG
Figure 3: Durning the treatment

jaims_3862_04.JPG
Figure 4: Durning the treatment

jaims_3862_05.JPG
Figure 5: Cut through of fistulous tract

jaims_3862_06.JPG
Figure 6: After Cut through of fistulous tract by Agnikarma


jaims_3862_07.JPG
Figure 7: After treatment i.e., During the follow-up

References

1. Sushruta Samhita. Yadavji Trikamji, Narayan Ram Acharya Kavyatirtha, editors. Varanasi: Chaukambha Surbharati Prakashan; Nidana Sthana 4/3. p. 280.

2. Sushruta Samhita. Yadavji Trikamji, Narayan Ram Acharya Kavyatirtha, editors. Varanasi: Chaukambha Surbharati Prakashan; Sutrasthana 33/4. p. 144.

3. Ashtanga Hridaya. Bramanad Tripathi, editor. Varanasi: Choukhamba Orientalia Academy; 2010. p. 487.

4. Gupta PJ. Ano-perianal tuberculosis--solving a clinical dilemma. Afr Health Sci. 2005 Dec;5(4):345-7. doi: 10.5555/afhs.2005.5.4.345. PMID: 16615850; PMCID: PMC1831950.

5. Charaka Samhita. Kashinath Pandey, Gorakhanath Chaturvedi, editors. Varanasi: Chaukhamba Bharati Academy; Nidana Sthana 8/20.

6. Charaka Samhita. Kashinath Pandey, Gorakhanath Chaturvedi, editors. Varanasi: Chaukhamba Bharati Academy; Nidana Sthana 8/23.

7. Sushruta Samhita. Yadavji Trikamji, Narayan Ram Acharya Kavyatirtha, editors. Varanasi: Chaukambha Surbharati Prakashan; Chikitsa Sthana 8/4. p. 439.

8. Charaka Samhita. Kashinath Pandey, Gorakhanath Chaturvedi, editors. Varanasi: Chaukhamba Bharati Academy; Chikitsa Sthana 12/96-97.

9. Ashtanga Hridaya. Bramanad Tripathi, editor. Varanasi: Choukhamba Orientalia Academy; Uttara Sthana 28/32.

10. Sushruta Samhita. Yadavji Trikamji, Narayan Ram Acharya Kavyatirtha, editors. Varanasi: Chaukambha Surbharati Prakashan; Chikitsa Sthana 17/26-28. p. 468.

11. Sushruta. Sushruta Samhita. Yadavji Trikamji, Narayan Ram Acharya Kavyatirtha, editors. Varanasi: Chaukambha Surbharati Prakashan; Nidana Sthana 4/13. p. 282.

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