E-ISSN:2456-3110

Review Article

Vrahat Dadimashtak

Journal of Ayurveda and Integrated Medical Sciences

2024 Volume 9 Number 10 OCTOBER
Publisherwww.maharshicharaka.in

Clinical efficacy of Vrahat Dadimashtak Choorna in Sangrahani w.s.r. to IBS: A Critical Review

Arora M1*, Malik P2
DOI:10.21760/jaims.9.10.22

1* Mohit Arora, Assistant Professor, Dept of Kayachikitsa, National College of Ayurveda and Hospital, Barwala, Haryana, India.

2 Pavitra Malik, Assistant Professor, Dept of Kayachikitsa, National College of Ayurveda and Hospital, Barwala, Haryana, India.

The purpose of this review article is to have a comparative review of Sangrahani with IBS (irritable bowel syndrome) with respect to modern medical science and to evaluate the efficacy of Vrahat Dadimashtak Choorna in treating Sangrahani w.s.r. to IBS. At present time Sangrahani is correlated with IBS based on symptoms like alternate episodes of constipation and diarrhea (Mahurbadham mahurdravam), Stool accompanied by the passage of a large amount of mucus (Mala Niskasana with Shabda and Manda Vedena), fatigue (Durbalata Sadan Alasya). According to Ayurvedic literature, the potency and efficacy of Ayurvedic classical preparations depend upon the Rasa Panchaka, Desh (region), Kal (time), Ritu (season), their preparation method, and route of administration. This article mentions the efficacy of Vrahat Dadimashtak Choorna in treating Sangrahani w.s.r. to IBS. As per Acharya Sharangdhar, Vrahat Dadimashtak Choorna is also very useful for the treatment of other disorders like Atisaar (diarrhea), Gulma (abdominal tumor/abdominal lump), Mandagni (Improper digestion), Kasa (cough). All the contents of Vrahat Dadimashtak Choorna have been evaluated according to the research done by various research scholars. The efficacy has also been tested according to the Rasa, Guna, Virya, Vipaka described in Ayurvedic text.

Keywords: Vrahat Dadimashtak Choorna, Atisara, Gulma, Sangrahani, IBS

Corresponding Author How to Cite this Article To Browse
Mohit Arora, Assistant Professor, Dept of Kayachikitsa, National College of Ayurveda and Hospital, Barwala, Haryana, India.
Email: 		Arora M, Malik P, Clinical efficacy of Vrahat Dadimashtak Choorna in Sangrahani w.s.r. to IBS: A Critical Review. J Ayu Int Med Sci. 2024;9(10):133-138.
Available From
https://jaims.in/jaims/article/view/3924

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2024-10-09 2024-09-19 2024-09-28 2024-10-09 2024-10-19
Conflict of Interest Funding Ethical Approval Plagiarism X-checker Note
None Nil Yes 13.38

© 2024by Arora M, Malik Pand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

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Mohit A et al. Clinical efficacy of Vrahat Dadimashtak Choorna in Sangrahani

Introduction

Ayurveda has described the importance of Agni and its importance in detail. Grahani is the main site of Agni where all metabolic activities take place. Grahani means Grahana (acceptance of food) and its functions are Dharana (storage of food for some time), Pachana (digestion), Shoshana (absorption) and Munchan (forwarded to colon). Acharya Charak, Susruta and Vagbhatta described four types of Grahani based on Doshas. Acharya Madhavakar has explained two more type of Grahani i.e., Sangrahani and Gatigrahani. The symptoms of Vyadhi Sangrahani can be co-related with IBS in modern science. One of the references to the concept of an irritable bowel and Sangrahani appeared in the Rocky Mountain Journal on 1950.

Symptoms of SangrahaniSymptoms of IBS
Paksham Masa Dashahadava NityamvapyathamunchyatConstipation is the most consistent feature in IBS
Mahurbadham Mahurdravam Alternate episodes of constipation and diarrhoea
Antrakoojana Abdominal distension increase belchingAbdominal distension increases belching
Mala Niskasana with Shabda and Manda Vedena Stool accompanied by passage of large amount of mucus
Durbalata Sadan Alasya Fatigue
Divaprakopo RatrisantiNocturnal diarrhoea absent in IBS
Kati ShoolaBack pain

The symptoms of IBS in modern science and Sangrahani in Ayurveda are similar.

The cardinal symptom of Sangrahani in Ayurveda is ‘Pakvamva Sarujamputi Mahurbadhm Mahurdravam’ and ‘Malam Sangrahaya Sangrahaya Kadachit Atirechayet’. The term Sarujam indicates pain, Mahurbadam Mahurdravam indicates alternate episodes of constipation and diarrhoea and Malamsangraha Sangraha Kadachit Atirechaat indicates the change in stool frequency.[1],[2]

Ayurveda has a vast range of drugs for the treatment of gastrointestinal disorders. Vrahat Dadimashtak Choorna is one of the Ayurvedic medicine for the management of gastrointestinal disorder and metabolic disorder. Acharya Sharangdhar has explained Vrahat Dadimashtak Choorna is useful for many disorders like Atisaar (Diarrhoea), Gulma (Abdominal tumor / Abdominal lump), Grahani (Sprue), Mandagni (Improper digestion) etc.[3] Ayurvedic properties, Chemical composition and Medicinal Properties of ingredient drugs of Vrahat Dadimashtak Choorna are mentioned in following table (Table 1-2).

The constituents of Vrahat Dadimashtak Choorna like Sunthi, Jeerak, Dhaniya and Dadimbeej having Deepan and Grahi properties, so it is quite effective in different types of Atisara. The Ela, Tvak, Tungshir, Pippali and Jeeraka of this Choorna having Deepana, Rochana and Kshayahara properties. This Choorn has Nagakesar, Sunthi, and Jeeraka having Deepana, Grahi and Grahnidoshahara properties. C. tamala shows Gastroprotective activity in Experimental gastric ulcers in rats.[4]

Table 1: Ayurvedic and chemical properties of ingredient drugs of VrahatDadimashtakChoorna[5],[6]

SNIngredientPropertiesPart usedChemical composition
1.Dadimbeeja (Pomegranate) (Punica granatum)Rasa - Madhura, Kashaya, Amla.
Guna - Laghu, Snigdha
Virya - Anushna
Vipaka - Madhura, Amla
Karma - Rochana, Kandughana, Krimghana, Sangrahi, Kanthaya.
Dosha Prabhava - Kapha-Vata Hara.		Seedpunicic acid[7]
2.Misri (crystalline sugar)Rasa - Madhur
Guna - Sheet, Sar, Laghu.
Virya - Sheet
Vipaka – Madhura.
Karma - Ruchya, Dahnut, Moorchchhahar, Chhardighna, Jwaraghna.
Dosha Prabhava - Vata Pitta Har		-------crystalline sugar
3.Pippali (Long peeper)
Piper longum		Rasa – Katu.
Guna - Laghu, Snigdha, Tikshana.
Virya - Anushna.
Vipaka - Madhura.
Karma - Aanahaghna, Vrishya Dipaniya, Shoolprashamniya, Pachaniya, Jwarahara.
Dosha Prabhava - Kapha-Vata Har		Fruitspiperine, iperonaline, piperettine, asarinine, pellitorine, piperundecalidine, piperlongumine[8]

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4.Pippalimula (long peeper root)Rasa - Katu, Tikta.
Guna - Laghu, Snigdha, Tikshana.
Virya - Ushna.
Vipaka - Katu.
Karma - Aanahaghna, Vrishya, Dipaniya, Shoolprashamniya, Pachaniya, Jwarahara.
Dosha Prabhava - Kapha-Vata Hara		Rootspiperine, iperonaline, piperettine, asarinine, pellitorine, piperundecalidine, piperlongumine
5.Yawani (Bishop's weed) (Trachyspermum ammi)Rasa - Katu Tikta.
Guna - Laghu, Ruksha, Tikshana.
Virya - Ushna.
Vipaka - Katu;
Karma - Rochan, Dipan, Jantughna, Anuloman, Vednasthapan.
Dosha Prabhava - Vata Kapha Shamak		Seedscarbohydrates, tannins, glycosides, saponins, flavone and nicotinic acid[9]
6.Maricha (Black peeper) (Piper nigrum)Rasa - Katu;
Guna - Laghu, Tikshana; Virya - Ushna;
Vipaka - Katu.
Karma - Chakshushya, Dipaniya, Shoolprashamniya, Krimghana.
Dosha Prabhava - Kapha-Vata Har		FruitsPiperine, lauratic acid, palmitic acid, ascorbic acid[10]
7.Dhanyaka (Coriander) (Coriandrum sativum)Rasa - Kashaya;
Guna - Laghu, Ushana, Ruksha;
Virya - Ushna;
Vipaka - Madhura;
Karma - Dipaniya, Pachaniya, Vatanulomaka, Mutral’
Dosha Prabhava - Tridosha Shamaka		Fruitsapigenin, luteolin, diosmin, dihydroquercetin, catechin, chrysoeriol, dicoumarin,
4-hydroxycoumarin (Oganesyan et al., 2007)
8.Jiraka (Cumin seed) (Cuminum cyminum)Rasa - Katu.
Guna - Laghu, Ruksha.
Virya - Ushna.
Vipaka – Katu.
Karma - Rochan, Dipana, Vatanulomaka, Vednasthapan, Raktashodhaka.
Dosha Prabhava - Kapha-Vata Har		Seedscuminaldehyde, limonene, αand βpinene, cineole, cymene, αand γterpinene,
safranal and linalool[11]
9.Sonth (Dry zinger) (Zingiber officinale)Rasa - Katu.
Guna - Laghu, Snigdha.
Virya - Ushna.
Vipaka - Madhur.
Karma - Rochana, Dipan, Shoolprashaman, Raktashodhak, Aampachan Dosha Prabhava - Vata-Kapha Shamak		Rhizomegingerols, shogaols, paradols and zingerone zingeberene, curcumene, farnesene[12]
10.Tugakshiri (Bamboo manna) (Bambusa arundinacea)Rasa - Madhura, Kashaya.
Guna - Laghu, Ruksha, Tikshana.
Virya - Shita.
Vipaka - Madhur.
Karma - Varnya, Kusthghna, Raktasthambhana, Trishnaanigraha.
Dosha Prabhava - Kapha-Pitta Hara		LatexOxalic acid, reducing sugar, resins, waxes, HCN, benzoic acid (Ghosh et al., 1938)
11.Tvak (Cinnamomum zeylanicum)Rasa - Katu Tikta.
Guna - Laghu, Tikshana, Ruksha.
Virya - Ushna.
Vipaka - Katu. Karma - Rochana, Kandughana, Krimghana, Sangrahi, Kanthaya.
Dosha Prabhava - Kapha-Vata Hara		BarksCinnamaldehyde, trans-cinnamaldehyde, eugenol, linalool[13]
12.Ela (Cardamom) (Elettaria cardamomum)Rasa - Madhura Katu.
Guna - Laghu, Ruksha.
Virya - Shita.
Vipaka - Madhura.Karma - Rochana, Dipana, Krimghana.
Dosha Prbhava - Tridosh Hara		Fruitsprotocatechualdehyde, protocatechuic acid, alpha-terpinyl acetate, linalyl acetate, limonene, linalool, limonene[14]
13.Patra (Cinnamomum tamala)Rasa - Madhura.
Guna - Ushna, Pichchhila, Laghu.
Virya - Ushna
Vipaka - Katu
Karma - Arsoghna, Hrullasa, Rochan, Peenusghna
Dosha Prbhava - Kaph Vata Hara[26]		LeafFuranosesquiterpenoids, Furanogermenone, β- caryophyllene, sabinene, curcumenol[15]
14.Nagakesar (Cobra’s saffron) (Mesua ferra)Rasa - Kashaya, Tikta
Guna - Laghu, Ruksha
Virya - Anushana
Vipaka - Katu
Karma-  Stambhana, Krimghana;
Dosha
Prabhava-Vata-Pitta Hara		SeedsMesuarin, Mesuein, Ferrxanthone (Walia, S., et.al, 1984)

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Table 2: Medicinal properties of Each Constituents of VrahatDadimashtakChoorna[16]

SNDrugsCharakSusrutaP.V. SharmaUses in Nighantus
1.DadimbeejaHridya ChhardinigrahaParushakadi GanaRochanGrahi, Ruchya, Deepana
2.MisriRuchya,
3.Pippali/ PippalimulaKasahar, Dipniya, TraptighnaUrdhwabhag-Har, PipplyadiganaKasaharSwas, Kasa, Agnivardhaka, Gulmaghna, Kshyapahama
4.YawaniSheetprashamana--Shoolprash AmanaGulmaghna
5.MarichaDipniya, Shoolprashamana KramighnaShirovirechanPipplyadigana
Tryausna		DeepanDeepana, Sarvakashara
6.DhanyakaTrashnanigrha SheetprashamanaGuduchyadiganaTrashnani GrhaSwasakashara, Rochana Grahi
7.JirakaShoolprashamana ShirovirechanPipplyadiganaDeepanGulma, Atisaar, Grahani, Kshaya
8.SonthTraptighna, Arsoghna, Dipniya, Shoolprashamana TrashnanigrhaPipplyadigana TryausnaTraptighnaAtisaar, Agnivardhaka, Grahanidosha
9.Tugakshiri---------Kasa, Kshaya
10.Tvak---EladiganaChhedanaSwasakashara, Kshaya, Peenus, Aruchi, Hrullasa
11.ElaShwashar, Angamarda Prashamana, ShirovirechanEladiganaDahaprash AmanaSwasakashara, Kshaya, Rochana, Deepana
12.Patra---EladiganaChhedanaPeenus, Aruchi, Hrullasa
13.NagakesaraEladigana Priyangawadigana AnjanadiganaRaktastam BhanaAtisaara, Agnivardhaka, Grahanivikara

Conclusion

By this all review work, It is concluded that Vrahat Dadimashtak Choorna is very good drug to treat Sangrahani w.s.r. to IBS. And now, we are now able to justify the claims of old Ayurvedic text on the modern research parameters.

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