Journal of Ayurveda and Integrated Medical Sciences

2024 Volume 9 Number 12 DECEMBER
Publisherwww.maharshicharaka.in

Clinical study to evaluate the effect of Suvarnaprashan Yoga on growth and development in children

Kumar S1*, Minakshi2, Chaudhary V3
DOI:10.21760/jaims.9.12.7

1* Sahil Kumar, Post Graduate Scholar, Department of Kaumarbhritya, Rajiv Gandhi Government Post Graduate Ayurvedic College and Hospital, Paprola, Himachal Pradesh, India.

2 Minakshi, Professor, PG Department of Kaumarbhritya, Rajiv Gandhi Government Post Graduate Ayurvedic College and Hospital, Paprola, Himachal Pradesh, India.

3 Vijay Chaudhary, Principal cum Dean, PG Department of Kaumarbhritya, Rajiv Gandhi Government Post Graduate Ayurvedic College and Hospital, Paprola, Himachal Pradesh, India.

Suvarnaprashan Yoga, an ancient Ayurvedic practice, is a unique combination of Suvarna and herbal formulations, primarily used to enhance mental, physical, and immune health in children. This practice has been a part of traditional medicine for centuries, especially in the context of preventive healthcare and cognitive development. Suvarnaprashan is typically administered in the form of a liquid preparation, which contains Suvarna Bhasma (colloidal gold), along with various herbal ingredients like Brahmi, Vacha, and Shankhapushpi, known for their neuroprotective and cognitive-enhancing properties. The main aim of Suvarnaprashan Yoga is to stimulate the mind, enhance intelligence, improve memory, and promote overall vitality in children. This research article explores the scientific basis, therapeutic benefits, and clinical applications of Suvarnaprashan Yoga, with a focus on its pharmacological mechanisms, safety, and effectiveness. Through a comprehensive review of existing literature, this study seeks to evaluate the contemporary relevance of Suvarnaprashan as an alternative or adjunct to modern medical treatments for cognitive and developmental disorders. Further clinical trials are recommended to validate its efficacy in pediatric healthcare, with a particular emphasis on long-term outcomes.

Keywords: Suvarnaprashan Yoga, Neuroprotective, Cognitive, Children

Corresponding Author How to Cite this Article To Browse
Sahil Kumar, Post Graduate Scholar, Department of Kaumarbhritya, Rajiv Gandhi Government Post Graduate Ayurvedic College and Hospital, Paprola, Himachal Pradesh, India.
Email:
Kumar S, Minakshi, Chaudhary V, Clinical study to evaluate the effect of Suvarnaprashan Yoga on growth and development in children. J Ayu Int Med Sci. 2024;9(12):58-66.
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https://jaims.in/jaims/article/view/4125

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2024-11-08 2024-11-18 2024-11-28 2024-12-09 2024-12-22
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© 2024by Kumar S, Minakshi, Chaudhary Vand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

Download PDFBack To ArticleIntroductionAim and ObjectivesMaterials and MethodsResultsDiscussionConclusionReferences

Introduction

Childhood is a critical period of growth and development. This period also presents challenges regarding low immunity, with a greater risk of illness due to poor cleanliness and inadequate nutrition. A nurturing environment is essential for children's growth and development, providing safety and stimulation for learning. Encourage regular outdoor play to promote physical and mental well-being.

In Ayurveda, there are sixteen essential Samskara for children; Suvarnaprashan is one of them. It is a process in which Suvarna Bhasma is administered with pure Ghrita and Madhu in liquid and paste form. In Ayurveda, there are sixteen essential Samskara for children; Suvarnaprashan is one of them. It is a process in which Suvarna Bhasma is administered with pure Ghrita and Madhu in liquid and paste form. Suvarnaprashan in children can be mainly implicated in two contexts of Ayurveda: Lehana (Supplementary feeds) and Jatakarma Samskara (Newborn care). The literary meaning of Lehana is licking. So, the process of licking and gulping is called Lehana. The substance subjected to Lehana is called Lehya. In Kashyapa Samhita, a separate chapter called Lehadhyaya is dedicated to Lehana Karma explaining various forms of Lehana. The purpose of Lehana karma is to promote physical and mental well-being and prevent diseases by establishing immunity. Jatakarma is the birth ceremony that helps the baby transcend from intrauterine life to extra-uterine life. According to Charaka Samhita, after the initial stabilization of the baby (Prana Pratyagamana) and cord cutting, Jatakarma should be performed. First of all, the child should be given Madhu and Ghrita. Thereafter, milk from the right breast should be given to the child.[1] Sushruta Samhita has opined Jatakarma as cleaning the vernix on the newborn’s body, clearing the newborn’s mouth by Saindhava and Sarpi and placing a ghee-soaked cotton on the baby’s head. This is followed by cutting the umbilical cord at a distance of eight Angula from the baby’s skin and tying it by a thread that is tied to the baby’s neck.[2] After this baby is made to lick Suvarna Bhasma mixed with Madhu and Ghrita.

There are various formulations of gold along with herbal drugs explained by different Acharyas for prolonged usage in children.

Sushruta Samhita explains Suvarnaprashan Yoga, which contains Brahmi, Shankhapushpi, Madhu, Ghrita and Suvarna Bhasma in it. This Suvarnaprashan Yoga enhances the child’s body, memory power (Smaranshakti),strength (Bala) and wisdom (Buddhi).[3]

Ayurveda has a broader vision than modern immunization. It was preferred to boost immunity and thus avoid many ailments, along with gaining physical, mental, social and spiritual strength to lead a healthy and happy life. The effects of Suvarnaprashan mentioned in Samhitas are owing to the quick absorption and assimilation of gold nanoparticles contained in Suvarnaprashan. In recent years, there has been a renewed interest in drug discovery strategies where natural products and traditional medicines are re-emerging as attractive options[4] and hence, renewed interest in agents like Suvarna Bhasma. Recent research has revealed that gold nanoparticles exhibit size-dependent absorption through rat skin and intestine, with smaller particles (~15 nm) absorbed more than larger particles (>100 nm).[5] Nanoparticles can also be absorbed through a sublingual route directly into the bloodstream.[6]

Growth and development begin from conception and ends at maturity. Early childhood is a time of tremendous growth and development. When compared with the first year of life, a decreased growth rate is seen in toddlers. It is the age group, where parents express concern about poor growth. “Suvarnaprashan”, has been used in clinical practice for thousands of years but still there is a lack of scientific evidence to support its beneficial effects, particularly regarding its impact on height, weight, cognitive abilities, and immunity. Today, substantial scientific evidence is needed to support the beneficial effects of Suvarnaprashan. Therefore, the present study has been planned to provide reliable data to determine if Suvarnaprashan has a positive impact on these factors and establish its safety and efficacy on growth and development in children with following aims and objectives.

Aim and Objectives

1. To study the effect of Suvarnaprashan Yoga on growth and development in children.
2. To evaluate the clinical safety of Suvarnaprashan Yoga in children.


Materials and Methods

Selection of study subjects

The study subjects were randomly selected from OPD and IPD of P.G. Department of Kaumarbhritya, Rajiv Gandhi Government Post Graduate Ayurvedic College and Hospital, Paprola, Distt. Kangra (H.P.). A total of 218 study subjects between 0 to 2 years of age were registered for clinical trial, out of them 18 did not turn up for follow-up. These 18 study subjects were dropped out from the study and trial was completed in remaining 200 study subjects.

Intervention

A total of 218 selected study subjects were randomly divided into two groups. In Group A, 105 study subjects were managed with Suvarnaprashan Yoga at a dose of one drop/kg/day orally. In Group B, 113 study subjects were managed with a placebo drug, i.e., Madhu and Ghrita, at a dose of three drops/kg/day orally (one drop of Ghrita and two drops of Madhu).

Duration of trial: 12 weeks.

Follow ups: Follow up at 4thweek, 8th week and at the time of completion, and last follow up after 15th day and 30th day of completion of study.

Inclusion Criteria

  • Healthy children of age up to two years, irrespective of gender, religion, socio-economic status, etc.
  • Parents of study subjects willing to participate in the trial.

Exclusion Criteria

  • Children above two years of age.
  • Children with any congenital disorder, syndrome, etc.
  • Children with acute illness.
  • Children who are malnourished.
  • Parents of the study subjects not willing to participate in the trial.

Withdrawal Criteria

  • Study subject showing any feature of adverse drug reaction.
  • Parents of the study subjects not willing to continue with treatment.

Assessment Criteria

Objective Criteria of Assessment

Anthropometry

The following Anthropometric measurements were recorded:

  • Weight in kg.
  • Height in cm.
  • Chest circumference (CC).
  • Mid-upper arm circumference (MUAC).
  • Mid-thigh circumference (MTC).

Subjective Criteria of Assessment

  • Developmental milestone achievement: Trivandrum Developmental Screening Chart (TDSC) is used for assessment of Development before and after trial.
  • Reduction in the frequency of episodes of common illnesses.

To assess the improvement in milestones, a scoring system was adopted based on the Trivandrum Developmental Screening Chart (TDSC) The scoring ranges from not attained to attained at lower limit as described below:

MilestonesGrade
Not Attained3
Attained at Upper Limit1
Attained between Upper and lower limit2
Attained at Lower limit0

Items used in TDSC (Age range: 0-2yrs)

SNTest items3%97%
1.  Social smile1 day2 months
2.  Eyes follow pen/ pencil1 mo 3 days3 months
3.  Holds head steady1 mo 3 days3 mo 24 days
4.  Rolls from back to stomach2 mo 21 days4 mo 24 days
5.  Turns head to sound of bell/ rattle3 months5 mo 24 days
6.  Transfer objects hand to hand4 mo 3 days7 months
7.  Raises self to sitting position5 mo 24 days11 months
8.  Standing up by furniture6 mo 9 days11 months
9.  Fine prehension pellet6 mo 24 days11 months
10. Pat a cake6 mo 24 days12 mo 21 days
11. Walks with help7 mo 24 days13 months
12. Throws ball9 mo 15 days16 mo 24 days
13. Walks alone9 mo 27 days17 mo 12days
14. Says two words11 mo 6 days19 months
15. Walk backwards11 mo 6 days19 mo 15 days
16. Walk upstairs with help12 mo 6 days24 mo 15 days
17. Points to parts of doll (3parts)15 mo 9 days24  mo 15 days

**This table shows the upper and lower limits of items used for the evaluation.


Statistical Analysis

Data was statistically analysed by using appropriate tests. For non-parametric data “The Wilcoxon Signed Rank Test” was used for individual groups and “Mann Whitney ‘U’ statistical test” was used for intergroup comparison.

Results

Effect of therapy on anthropometric parameters

AnthropometryGroupsMean score%SD±SE±W valueP value
BTATDiff.
Body weightGroup A11.0011.900.908.180.290.032485< 0.001
Group B10.0010.300.303.003.590.3610930.056
HeightGroup A80.0080.200.200.2513.551.3510340.023
Group B80.2080.350.150.1811.991.207340.207
Chest CircumferenceGroup A46.8347.100.270.576.700.6713520.002
Group B46.6046.900.300.644.550.4616080.005
Mid upper arm circumferenceGroup A12.4012.600.201.611.700.172318< 0.05
Group B12.3012.400.100.831.280.131303< 0.05
Mid-thigh CircumferenceGroup A13.0113.200.191.460.060.015050< 0.05
Group B13.0012.150.151.150.050.015050< 0.05

Intergroup Comparison of anthropometric parameters between Group A and Group B

Anthropometry Group A
and Group B
Mean DifferenceT valueP value
Body weight11.188156< 0.001
Height0.438999.5000.010
Chest Circumference1.219805.5000.551
Mid upper arm circumference2.449292.500> 0.05
Mid-thigh Circumference2.615152< 0.001

Intergroup comparison of developmental milestones between Group A and Group B

Milestones(Group A vs Group B)Mean DifferenceT valuep value
Holds head steady39.31%13362.00< 0.001
Rolls from back to stomach78.8313588.00< 0.001
Raises self to sitting position83.3213983.00< 0.001
Standing up by Furniture83.1914117.500< 0.001
Walks with help85.814269.00< 0.001
Walks alone85.9814045.500< 0.001
Walks backward82.8413754.00< 0.001
Walks upstairs with help88.5913820.00< 0.001
Transfer objects hand to hand85.314142.00< 0.001
Fine
prehension Pellet
84.7514246.500< 0.001
Pat a cake80.7513834.500< 0.001
Points to part of doll (3 parts)80.0014036.00< 0.001
Social smile82.6514052.500< 0.001
Eyes follow pen/pencil83.2114086.500< 0.001
Throws ball84.9614395.00< 0.001
Turns head to the sound of bell/rattle78.5913978.500< 0.001
Says two words73.8013794.00< 0.001

Effect of therapy on developmental milestones

MilestonesGroupsMean score%SD±SE±W valuep value
BTATDiff.
Holds head steadyGroup A1.810.190.9954.690.610.063321.000< 0.001
Group B1.170.920.1815.380.390.04325.000< 0.001
Rolls from back to stomachGroup A1.090.150.9688.070.600.063081.00< 0.001
Group B1.191.060.119.240.310.0391.00< 0.001
Raises self to sitting positionGroup A1.070.120.9588.780.520.053570.00< 0.001
Group B1.11.020.065.450.240.0236.000.008
Standing up by FurnitureGroup A1.140.121.0491.220.510.053828.00< 0.001
Group B1.121.030.098.030.290.0345.000.004
Walks with helpGroup A1.230.111.1291.010.570.064005.00< 0.001
Group B1.151.090.065.210.240.0221.000.031
Walks aloneGroup A1.070.090.9992.520.520.053655.00< 0.001
Group B1.071.000.076.540.260.0328.000.016
Walks backwardGroup A1.190.121.0789.910.690.073240.00< 0.001
Group B1.131.050.087.070.310.0328.000.016
Walks upstairs with helpGroup A1.140.121.0188.590.630.063321.00< 0.001
Group B1.201.120.075.830.260.0336.000.008
Transfer objects hand to handGroup A1.200.101.1192.50.580.063828.00< 0.001
Group B1.111.030.087.200.270.0336.000.008
Fine
prehension Pellet
Group A1.130.121.0391.150.460.054005.00< 0.001
Group B1.251.170.086.40.310.0328.000.016
Pat a cakeGroup A1.130.121.0189.380.580.063486.00< 0.001
Group B1.161.060.108.620.330.0345.000.004
Points to part of doll (3 parts)Group A1.100.150.9687.270.450.053741.00< 0.001
Group B1.101.020.087.270.270.0336.000.008
Social smileGroup A1.140.131.0188.590.540.053741.00< 0.001
Group B1.181.110.075.930.260.0328.000.016
Eyes follow pen/pencilGroup A1.080.130.9789.810.480.053655.00< 0.001
Group B1.081.010.076.480.290.0321.000.031
Throws ballGroup A1.150.101.0692.170.400.044371.00< 0.001
Group B1.111.030.087.200.310.0328.000.016
Turns head to the sound of bell/rattleGroup A1.180.141.0387.280.540.053828.00< 0.001
Group B1.151.050.108.690.330.0345.000.004
Says two wordsGroup A1.120.210.9282.140.490.053486.00< 0.001
Group B1.201.100.108.330.330.0345.000.004

Effect of therapy on hematological and biochemical parameters

MilestonesGroupsMean score%SD±SE±W valueP value
BTATDiff.
Hb gram%Group A11.4711.490.020.170.080.021738> 0.05
Group B11.8911.900.010.080.090.031057> 0.05
TLCGroup A9.058.990.060.73.060.351208> 0.05
Group B6.546.510.040.62.080.21616> 0.05
ESRGroup A15.3315.040.291.894.350.441340> 0.05
Group B6.546.500.040.612.080.21602> 0.05
SGOTGroup A41.0339.002.034.9415.260.151648> 0.05
Group B31.19301.193.818.180.83633> 0.05
SGPTGroup A29.4723.945.5318.7615.891.591707> 0.05
Group B27.9525.002.9510.5510.891.091020> 0.05
Serum CreatinineGroup A0.580.570.011.720.190.0236> 0.05
Group B0.750.760.011.330.110.011115> 0.05
Blood ureaGroup A26.1326.790.662.528.220.82636> 0.05
Group B27.6027.500.100.364.250.43123> 0.05

Intergroup comparison of hematological and biochemical parameters between Group A & B

Lab investigations
(Group A vs Group B)
Mean DifferenceT valueP value
Hb gram%0.038396> 0.05
TLC1.310879> 0.05
ESR2.511001> 0.05
SGOT6.1310715> 0.05
SGPT8.2110515> 0.05
Serum Creatinine3.059104> 0.05
Blood urea2.889762> 0.05

Intergroup comparison of frequency of common illness between Group A and Group B

Common illnesses
(Group A vs Group B)
Mean DifferenceT valueP value
Cough33.8210427> 0.05
Running nose3510552> 0.05
Nasal blockage19.5910550> 0.05
Constipation15.2510550> 0.05
Loose stools29.6410500> 0.05
Abdominal Colic4.08101000.904
Vomiting22.8710400< 0.05
Fever6.6610150> 0.05
Physiological Jaundice4.88101500.808

Effect of therapy on frequency of common illness

Common
illnesses
GroupsMean score%SD±SE±W valueP value
BTATDiff.
CoughGroup A0.350.130.2262.850.540.05136< 0.001
Group B0.310.220.0929.030.290.03450.004
Running noseGroup A0.320.160.16500.390.04120< 0.001
Group B0.330.280.05150.220.0215> 0.05
Nasal blockageGroup A0.410.240.1741.460.380.04153< 0.001
Group B0.320.250.0721.870.260.0320< 0.05
ConstipationGroup A0.470.320.1531.910.360.04120< 0.001
Group B0.300.250.0516.660.220.0215> 0.05
Loose stoolsGroup A0.330.200.1339.390.340.0391< 0.001
Group B0.410.370.049.750.200.0210> 0.05
Abdominal ColicGroup A0.300.210.0826.660.270.03450.004
Group B0.310.240.0722.580.260.0328< 0.05
VomitingGroup A0.320.200.1237.50.330.0378< 0.001
Group B0.410.350.0614.630.220.0215> 0.05
FeverGroup A0.300.210.0826.660.270.0345< 0.05
Group B0.300.240.0620.000.240.0221< 0.05
Physiological JaundiceGroup A0.410.350.0614.630.240.02210.031
Group B0.410.370.049.750.200.20100.125




Discussion

Pharmacodynamic Properties and Pharmacological Action

DrugPharmacodynamic propertiesAction on DoshaOther PropertiesPharmacological properties
BrahmiRasaTikta, KashayaMadhuraVata-kapha shamana and SarvadoshaharaHridya, Rasayana, Deepanam, Medhya rasayanam, Swarya, Smritiprada, Buddhi, Prajashakti, Medhashaktivardhana, Unmada vinashini.Antidepressant, Memory enhancing effect, Gastroprotective activity, Antioxidant activity, Anti-inflammatory, Cognitive enhancement.
GunaHima, Sara, Laghu
VeeryaSheeta
VipakaSwadu
PrabhavaMedhya
Shankha
Pushpin
RasaKatu, Tikta, KashayaTridoshashamaka and Vata-pitta shamakaMedhya, Rasayana, Manasrogahrit, Unmadanashaka, Nadi balya, Swarya.Learning, Memory and behaviour, Antioxidant activity, Antidepressant, Antistress, Brain nourishment.
GunaSara, Ushna
VeeryaUshna
VipakaKatu
PrabhavaMedhya
Suvarna BhasmaRasaMadhuraTridoshashamakRasayana, Deepana, Medhasmritiprada, Brimhana, Ojovarddhaka, Garaharam, Kantivardhaka, Vagshuddhikara, Vishanashaka,
Kshayanashaka, Unmadanashaka, Jwarahara, Shoshahara.
Anti-inflammatory and Immunomodulatory effect, Increased brain function, Antioxidant property, Cognition and learning, Anti-stress and depression.
GunaSnigdha, Laghu
VeeryaSheeta
VipakaMadhura
MadhuRasaMadhura, KashayaTridoshashamakAtisara, Chhardi, Visha vikara.Antioxidant property,
Anti-inflammatory effect, Antibacterial activity.
GunaRuksha, Sheeta, Guru, Picchila, Sukshmamarganusari, Yogavahi
VeeryaSheeta
VipakaMadhura

  • Most of the ingredients of Suvarnaprashan Yoga are predominantly Madhura and Tikta Rasa, with Laghu, Sara, Guru and Snigdha Guna, Sheeta Veerya and Madhura Vipaka. Madhura Rasa contains predominantly Jala Mahabhuta which plays a significant role in enhancing the ability of mind. It may be the reason Madhura Rasa contribute to the proper functioning of senses. Ojovarddhaka property of Madhura Rasa plays an important role in enhancing the child’s immune system.

  • The Laghu, Sara Guna promote the proper functioning of sensory activities, mind and acquisition of knowledge. Snigdha Guna also enhances the nourishment of the functional brain and reinforces the sensory activities.
  • Most of the ingredients have Madhura and Katu Vipaka, which contributes to overall enhancement of body’s metabolism and facilitates proper enzymatic secretions whereas, Madhura Vipaka has Saindriyaprasadaka properties which promotes the nourishment of sensory organs and other body tissues.
  • Brahmi and Shankhapushpi, both of which are Medhya drugs, are recognized for their specific impact on the cognitive performance achieved by inducing a neuro-nutrient effect and enhancing cerebral metabolism. Evidence-based studies also support these findings. Thus, by analyzing the benefits of Suvarnaprashan Yoga, it is evident that it aims to achieve comprehensive growth and development in children through its Rasayana This includes addressing Yuktikrita Bala (balanced strength), Brimhana Karma (nourishment and growth) and Medhya Karma (cognitive enhancement).
  • Suvarna Bhasma, with its micronized gold particles, enhances vitality and immune function, supports cognitive and physical development, and aids in detoxification. Together, these substances synergistically promote comprehensive physical and cognitive growth, ensuring balanced development and overall well-being.
  • No untoward effect of trial drug was observed during entire study period.

Conclusion

Group-A study subjects who were administered Suvarnaprashan Yoga showed better performance in growth and development parameters in comparison to the control group, specifically in terms of fine motor milestones and cognitive functions. Trial Group study subjects who were managed with Suvarnaprashan Yoga showed fewer episodes of illness during the study period in comparison to the control group. This may have been because of better optimization of immune system in response to the trial drug i.e., Suvarnaprashan Yoga.

Hematological and biological parameters remained within the normal range in both the groups before and after the trial. Thus, based on improvement in subjective and objective criteria in terms of growth and development, and fewer episodes of illness during the study period in comparison to the control group, it can be concluded that Suvarnaprashan Yoga may be given to the children to augment growth and development, especially during the rapid growth phase of early life.

References

1. Acharya YT, editor. Sushruta Samhita: with commentaries Nibandhasamgraha by Dalhana and Nyayacandrika by Gayadasa. Reprint 2012. Varanasi: Chaukhamba Surbharti Prakashan; Sharir Sthana Chapter 10, Verse 13. p. 388.

2. Parthasarathy A, editor-in-chief; Bhat BV, chapter editor. IAP Textbook of Pediatrics. 5th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2013. Ch 23. p. 31.

3. Sushruta Samhita Sharira Sthana Chapter 10, Verses 72, 74.

4. Patwardhan B, Vaidya AD. Natural products drug discovery: Accelerating the clinical candidate development using reverse pharmacology approaches. Indian J Exp Biol. 2010;48:220-7.

5. Sonavane G, Tomoda K, Sano A, Ohshima H, Terada H, Makino K. In vitro permeation of gold nanoparticles through rat skin and rat intestine: Effect of particle size. Colloids Surf B Biointerfaces. 2008;65:1-10.

6. Batheja P, Thakur R, Michniak B. Basic biopharmaceutics of buccal and sublingual absorption. In: Touitou E, Barry BW, editors. Enhancement in Drug Delivery. New York: CRC Press; 2007.

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