Introduction

Stomatitis is an inflammatory condition affecting the mucous lining of the mouth, which can result from various causes including infections, autoimmune diseases, medication side effects, and oral hygiene issues. It is commonly seen in clinical practice as a painful condition that hinders oral functioning, impacting eating, speaking, and overall quality of life. Treatment often involves topical treatments that alleviate pain and reduce inflammation.

पञ्चपल्लवजः क्वाथस्त्रिफलासम्भवोऽथ वा ।
मुखपाके प्रयोक्तव्यः सक्षौद्रो मुखधावने । ।६। ।
पटोल ननम्ब जब्बामालतीनपल्लवपञ्चपल्लवज श्रेष्ठ कषायो मुखिावने ॥ (यो.र.म.भाग 2)

Panchapallav gel is an Ayurvedic formulation tradi-tionally used to manage various oral health condi-tions, including stomatitis. This case study aims to explore efficacy, safety, & practical application of Panchapallav gel in treating stomatitis, based on clinical observations & relevant findings.

Background on Panchapallav Gel

Panchapallav gel is an Ayurvedic formulation that combines several medicinal plants known for their healing properties, particularly in oral health. The term “Panchapallav” translates to “Five Leaves,” reflecting its ingredients, which include:

Gel formulation of Panchapallav is designed for easy application on affected mucosal areas of mouth, providing relief from discomfort of stomatitis.

1. Oral Hydration: To ensure proper hydration and aid healing.
2. Avoidance of Spicy or Acidic Foods: To reduce irritation and promote healing.
3. Pain Management: The use of non-steroidal anti-inflammatory drugs (NSAIDs) for pain relief if needed, though the patient was primarily interested in a topical solution.

Method of Application

The patient was instructed to apply a thin layer of Panchapallav gel to the affected areas after meals, ensuring the gel remained in place for an extended period. The gel was applied thrice daily, once in the morning, afternoon and once before bed, for a period of 7 days.

Mode of Action in Stomatitis:

1. Anti-inflammatory effect: The herbal constituents reduce inflammation of the oral mucosa, helping relieve pain and swelling.
2. Antimicrobial activity: Neem contains bioactive compounds like flavonoids and tannins that inhibit microbial growth, reducing bacterial or fungal load in the mouth.
3. Astringent properties: Tannins help tighten and protect the mucosal lining, promoting healing and reducing further irritation.
4. Wound healing and mucosal regeneration: Some components stimulate epithelial regeneration and wound healing, speeding up recovery of ulcers or lesions in stomatitis.
5. Analgesic effect: The soothing and mild numbing effects help alleviate discomfort and burning sensations in the mouth.
6. Doshaghnata: Khaphapittaghna, Kaphagna, Pitta-shamak, Vranropak, Vranshodhan.

Clinical Observations

Local Examination of Mukhavran Colour

Sphota - Yellow-white with red border, shallow, round shaped no. multiples in nature

Tanubhi - Ulcer having depth of 0.5 -1mm

1. Day 1-2: The patient reported mild relief from pain after the first application. The gel appeared to coat the ulcers, reducing the direct exposure to irritants and food.
2. Day 3-4: Ulcers began to shrink slightly & pain intensity decreased. Patient noted less difficulty eating, particularly when consu. soft or bland foods.

as it did not require systemic medication or invasive procedures. The patient's experience aligns with the general clinical observations that topical Ayurvedic treatments can effectively manage minor cases of stomatitis.

Safety and Side Effects

No adverse reactions were reported during the treatment period. Panchapallav gel, due to its natural formulation, is considered safe for short-term use in managing oral mucosal conditions. However, as with any Ayurvedic or herbal product, potential allergic reactions to specific ingredients should be considered, particularly for individuals with sensitivities to plants like Neem or Jambu, Amra.

Conclusion

Panchapallav gel proves to be an effective and safe topical treatment for stomatitis, particularly in cases of aphthous stomatitis. Its anti-inflammatory, antimicrobial, and healing properties make it a suitable alternative or adjunct to conventional treatments. The patient in this case study experienced significant relief and healing within a short period, supporting the gel’s clinical efficacy in managing oral mucosal conditions. Further studies, including randomized controlled trials with larger sample sizes, are necessary to confirm the broader applicability and effectiveness of Panchapallav gel in different types of stomatitis and to establish long-term safety profiles.

References