Introduction
In modern era, stress is more than a temporary response to challenges. It is a pervasive, chronic condition that has infiltrated nearly every facet of human existence. According to World Health Organization (WHO), stress is now considered "health epidemic of 21st century".[1] It affects individuals regardless of socio-economic status, age or geography, and has profound consequences for personal well-being, workplace efficiency, and societal health. The digital age, while bringing convenience, has simultaneously amplified stressors. Constant connectivity, information overload, and pressure to perform in an increasingly competitive environment contribute to chronic stress. The COVID-19 pandemic exposed fragility of mental health infrastructure and intensified psychological burdens globally. As stress-related health issues escalate, it is critical to understand and address this phenomenon holistically.
Review Strategy
This narrative review collates existing literature from biomedical and Ayurvedic sources. Research articles were retrieved from databases such as PubMed, Google Scholar, and AYUSH Research Portal using terms like "stress", "occupational stress", "Ayurveda and stress", and "mental health interventions". Classical Ayurvedic texts were also referenced for traditional perspectives.
Definitions and Classifications of Stress
Stress is commonly defined as the body’s response to any demand or challenge. Hans Selye, a pioneering endocrinologist, introduced the General Adaptation Syndrome (GAS), which describes the three stages of stress response: alarm, resistance, and exhaustion.
Stress can be classified into various types:
- Acute stress: Short-term stress arising from recent or anticipated demands.
- Chronic stress: Long-term exposure to stressors leading to prolonged activation of the stress response system.
- Eustress: Positive stress that can motivate individuals.
- Distress: Negative stress that impairs functioning.
Understanding the type and duration of stress is essential for diagnosis and treatment.
Etiology of Stress
The causes of stress are diverse and multifactorial. Key contributors include:
- Occupational stress: High demands, long hours, lack of autonomy, and toxic work environments.[2]
- Financial stress: Debt, unemployment, and economic instability.
- Relationship stress: Interpersonal conflicts, divorce, and domestic violence.
- Academic stress: High expectations, exam pressure, and uncertain career prospects.[3]
- Technological stress: Constant notifications, cyber bullying, and digital fatigue.
- Pandemic-induced stress: Isolation, fear of infection, and loss of loved ones.[4]
- Each stressor impacts individuals differently based on personality, resilience, and support systems.
Biological Mechanisms of Stress
Stress triggers the hypothalamic-pituitary-adrenal (HPA) axis, leading to the release of cortisol, adrenaline, and norepinephrine. These hormones prepare the body for a "fight or flight" response, increasing heart rate, blood pressure, and glucose levels.[5]
Prolonged activation of this system disrupts physiological balance and can lead to: Immunosuppression, Metabolic syndrome, Insomnia and fatigue, Neuro inflammation Neuroscientific studies have shown that chronic stress alters brain structure and function, particularly in the hippocampus, amygdala, and prefrontal cortex.[6]
Health Consequences of Stress
Stress is linked with a wide range of health disorders, including:
- Cardiovascular diseases: Hypertension, atherosclerosis, and myocardial infarction.[7]
- Endocrine disorders: Type 2 diabetes and thyroid dysfunction.
- Mental health conditions: Depression, anxiety, PTSD, and panic disorders.[8]