E-ISSN:2456-3110

Review Article

Nagadantyadi Ghrita

Journal of Ayurveda and Integrated Medical Sciences

2025 Volume 10 Number 8 August
Publisherwww.maharshicharaka.in

Nagadantyadi Ghrita In Keeta Visha - A Review

Rohith KR1*, Avinash KV2, Pooja KS3
DOI:10.21760/jaims.10.8.34

1* Rohith KR, Post Graduate Scholar, Department of PG Studies in Agada Tantra, KVG Ayurveda Medical College, Sullia, Karnataka, India.

2 Avinash KV, Professor and HOD, Department of PG Studies in Agada Tantra, KVG Ayurveda Medical College, Sullia, Karnataka, India.

3 Pooja KS, Assistant Professor, Department of PG Studies in Agada Tantra, KVG Ayurveda Medical College, Sullia, Karnataka, India.

Background: Insect bites or stings are very common especially in the rural parts of India. Management of Keeta Visha has been explained in all the Ayurveda classics. Nagadantyadi Ghrita is a formulation indicated in various poisonous conditions by Acharya Charaka.

Aim: This study aimed at evaluating the pharmacological properties of Nagadantyai Ghrita and its effect on Keeta Visha.

Materials and Methods: This literature study was done by referring various Samhita’s, articles and online sources.

Observations and Results: There are 8 ingredients in Nagadantyadi Ghrita and among them all most all ingredients show Vedanasthapana, Vishagna and Shothahara properties.

Conclusion: Oral intake of Nagadantyadi Ghrita can manage the symptoms of Keeta Visha like pain, swelling, itching and burning sensation.

Keywords: Visha, Keeta Visha, Nagadantyadi Ghrita

Corresponding Author How to Cite this Article To Browse
Rohith KR, Post Graduate Scholar, Department of PG Studies in Agada Tantra, KVG Ayurveda Medical College, Sullia, Karnataka, India.
Email: 		Rohith KR, Avinash KV, Pooja KS, Nagadantyadi Ghrita In Keeta Visha - A Review. J Ayu Int Med Sci. 2025;10(8):208-211.
Available From
https://jaims.in/jaims/article/view/4685/

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2025-06-11 2025-06-26 2025-07-07 2025-07-18 2025-07-28
Conflict of Interest Funding Ethical Approval Plagiarism X-checker Note
None Nil Not required 11.95

© 2025 by Rohith KR, Avinash KV, Pooja KS and Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

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Download PDFBack To ArticleIntroductionAim and ObjectivesReview of LiteratureDiscussionConclusionReferences
Rohith KR et al. Nagadantyadi Ghrita In Keeta Visha

Introduction

Agada Tantra, one of the Ashta Angas of Ayurveda is the branch that deals with various types of poisonings, their symptoms and management. Visha generally classified into 2 types based on their source - Sthavara (Plant origin) and Jangama[1] (Animal origin). Among Jangama Visha, Keeta Visha[2] holds a pivotal role.

This can be due to the wide species variety among them, geographical distribution and specialities, more incidents of insect bites or stings throughout the word especially in the rural parts. Common symptoms of insect bites are Daha, Ruja, Sopha and Kandu.[3] However, the symptoms vary based on the type of insects and they can range from mild to severe manifestations upon the body. Management of Visha in general and Keeta Visha in specific can be found in the all the classical texts of Ayurveda as well as many traditional and regional books like Prayoga Samuchayam[4], Kriya Koumudi[5] and many more.

Aim and Objectives

This article is an attempt to study a formulation - Nagadantyadi Ghrita in Keeta Visha, a literary review.

Review of Literature

Arthropods make up the largest division in animal kingdom, comprising approximately 84% of all animals.[6] Among them, the insects which forms a major category has significant impact upon the ecosystem and humans in specific.

Ayurveda describes bites or stings of insects as Keeta Visha. Almost all the Samhita’s has explained in details regarding the Utpatti, Guna, Vega, Vega Lakshana, and Chikitsa of Keeta Visha. Some of the references of Keeta Visha are the following books:

1. Charaka Samhita, Chikitsa Sthana Chapter 8
2. Susruta Samhita, Kalpasthana, Chapter 8
3. Ashtanga Hrudaya, Uttarasthana, Chapter 37 & 43
4. Prayoga Samuchaya, Saptama Paricheda
5. Kriya Koumudi, Keeta Visha Prakaranam

Nagadantyadi Ghrita is a polyherbal formulation mentioned in Visharoga Chikitsa Adhyaya of Charaka Samhita.

Acharya Charaka has detailed this Yoga in the context of Gara Visha Chikitsa. This Yoga is useful in the management of Sarpa Visha, Keeta Visha and Gara Visha.

Ingredients

Nagadantyadi Ghrita contains 8 ingredients. The ingredients are in table 1.

Table 1: Ingredients of Nagadantyadi Ghrita

NameBotanical NameFamily
NagadantiCrotun oblongifoliusEuphorbiaceae
TrivritOperculina turpethumConvolvulaceae
DantiBaliospermum montanumEuphorbiaceae
DravantiCroton tigliumEuphorbiaceae
SnuhiEuphorbia nerifoliaEuphorbiaceae
MadanaphalaRandia dumetorumRubiaceae
GomutraCow’s urine
Mahisha SarpiClarified butter of buffalo milk

Method Of Preparation

Nagadantyadi Ghrita is prepared based on the Ghrita Murchana Vidhi[7] mentioned in the classics. One Aadhaka (3.072 KG) of Gomutra, all other ingredients in equal quantity are taken and processed in Murchita Mahisha Ghrita.

Mahish Ghrita is boiled first and into that required Kalka Dravya and Gomutra are added. It is then boiled until attaining the Ghrita Paka Lakshanas.

Mode of Administration

Internal / Oral

Dose

Reference regarding the dosage of Nagadantyadi Ghrita is not available in the literature. Hence, dosage can be fixed after assessing the condition of the patient and as per Vaidyayukti.

Probable Action of Nagadantyadi Ghrita

Acharya Charaka has explained Sarpakeeta Visharthanam Gararthanam Cha Shanthaye[8] i.e.; it is an effective remedy in poisoning from snake bites, insect bites and even in Gara Visha.

These effects can be validated by the study of properties and Rasa Panchaka of individual ingredients in the formulation. Properties of individual ingredients are in table 2.


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Rohith KR et al. Nagadantyadi Ghrita In Keeta Visha

Table 2: Rasa Panchaka of individual ingredients of Nagadantyadi Ghrita

DrugRasaGunaViryaVipakaKarma
Nagadanti[9]KatuGuru, TikshnaUshnaKatuKapha Vata Shamaka, Vishahara, Shoolahara
Thrivrit[10]Tikta, KatuLaghu, Ruksha, TikshnaUshnaKatuKaphapitta Samshodhana, Shothahara, Jwaragna
Danti[11]KatuGuru, TikshnaUshnaKatuKaphapitta Shamaka, Vedanasthapana, Shothahara, Vishagna
Dravanti[12]KatuGuru, Ruksha, TikshnaUshnaKatuKaphapittahara, Shothahara, Vishagna
Snuhi[13]KatuLaghu, TikshnaUshnaKatuKaphavatahara, Vedanasthapana, Shothahara, Vishagna
Madanaphala[14]Madhura, TiktaLaghu, RukshaUshnaKatuKaphavatashamaka, Shothahara, Vishagna, Vrananthaka
Mahisha Sarpi[15]MadhuraGuruSheetaMadhuraPitta Vata Hara, Kaphakara, Vrushyam
Gomutra[16]Katu, Tikta, KashayaTikshna, Laghu, KsharaUshnaKatuKaphavata Hara, Shoolahara, Kandugna, Deepana

Discussion

We can summarize the properties of ingredients in Nagadantyadi Ghrita in the form of graphical representations given below.

jaims_4685_01.JPG
Graph 1: Mode of Action of Nagadantyadi Ghrita based on Rasa

jaims_4685_02.JPG
Graph 2: Mode of Action of Nagadantyadi Ghrita based on Guna

jaims_4685_03.JPG
Graph 3: Mode of Action of Nagadantyadi Ghrita based on Virya

jaims_4685_04.JPG
Graph 4: Mode of Action of Nagadantyadi Ghrita based on Vipaka

jaims_4685_05.JPG
Graph 5: Doshaharatwa of ingredients of Nagadantyadi Ghrita

jaims_4685_06.JPG
Graph 6: Rogagnatha of ingredients of Nagadantyadi Ghrita

Conclusion

Nagadantyadi Ghrita is one of the Vishaghna yoga mentioned in the Charaka Samhita.


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From the study of Rasapanchaka and Doshagnatha properties of ingredients in Nagadantyadi Ghrita, we can understand that most of the drugs are Katu Rasa Pradhana, Tikshna and Ruksha in Guna. Out of all 8 ingredients, except Mahisha Sarpi all are Ushna Virya Dravyas and are having Katu Vipaka. Nagadanti, Danti, Snuhi and Gomutra shows Shoolahara properties. Thrivrit, Danti, Dravanti, Snuhi and Madanaphala has Shothahara property. Meanwhile Nagadanti, Danti, Dravanti, Snuhi and Madanaphala shows Vishaghna action. Kandughna Guna is shown by Gomutra whereas Madanaphala has Vranahara properties. Daha, Ruja, Sopha and Kandu are the primary symptoms of Keetavisha. Hence internal administration of Nagadantyadi Ghrita is effective in the management of Symptoms of Keeta Visha.

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