Journal of Ayurveda and Integrated Medical Sciences

2025 Volume 10 Number 9 September
Publisherwww.maharshicharaka.in

Panchakarma management of Diabetic Peripheral Neuropathy - A Case Report

Patel H1*, Tank N2
DOI:10.21760/jaims.10.9.53

1* Hiral Patel, PhD Scholar, Department of Panchakarma, Institute of Teaching and Research in Ayurveda, Jamnagar, Gujarat, India.

2 Neha Tank, Associate Professor, Department of Panchakarma, Institute of Teaching and Research in Ayurveda, Jamnagar, Gujarat, India.

Diabetic peripheral neuropathy is a type of nerve damage that can occur with uncontrolled diabetes. It affects 50% to 90% of patients and out of these 15-30% will have painful diabetic neuropathy. Conventional medicine has less than satisfactory result, hence there is need to find out safer & effective treatment from the sources other than the conventional medicine. Aim: The aim was to evaluate the role of Panchakarma treatment modalities in Diabetic peripheral neuropathy. Method: A 60-year-old female patient suffering from Type 2 Diabetes mellitus for 5 years, then she gradually developed Tingling sensation over bilateral lower limb, burning sensation, pain, sense of numbness, constipation for 3 years. There was no any Straightforward correlation with Ayurveda so treatment was done as per associated Dosha condition. Panchakarma procedure such as Nitya Virechana with Castor oil and Milk was given as per Agni and Kostha of the patient, Utsadana with Triphala-Nimba Churna with Nimba Taila and Dashamoola Ksheera Parisheka was done for 15 days. Assessment was done with Fasting and post-prandial blood sugar level, MTCNS (Modified Toronto clinical neuropathy score), Vibration perception threshold, Hot threshold, Cold threshold, Mono filament test was done by Neuropathy analyzer machine before and after completion of treatment. Result & Conclusion: Significant improvement was seen in subjective as well as objective parameters after the treatment. The study suggested that Nitya Virechana along with Bahirparimarjana Chikitsa can be useful to relieve the symptoms of Diabetic peripheral neuropathy.

Keywords: Bahirparimarjana Chikitsa, Diabetic peripheral neuropathy, Nitya Virechana

Corresponding Author How to Cite this Article To Browse
Hiral Patel, PhD Scholar, Department of Panchakarma, Institute of Teaching and Research in Ayurveda, Jamnagar, Gujarat, India.
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Patel H, Tank N, Panchakarma management of Diabetic Peripheral Neuropathy - A Case Report. J Ayu Int Med Sci. 2025;10(9):331-336.
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https://jaims.in/jaims/article/view/4760/

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2025-07-17 2025-07-28 2025-08-07 2025-08-17 2025-08-26
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© 2025 by Patel H, Tank N and Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

Download PDFBack To ArticleIntroductionCase ReportDiscussionConclusionReferences

Introduction

Diabetic neuropathy is a type of nerve damage that can occur with uncontrolled diabetes. High blood sugar can injure nerves throughout the body. Diabetic neuropathy most often damages nerves in the legs and feet. Depending on the affected nerves, diabetic neuropathy symptoms include pain and numbness in legs, feet and hands. It can also cause problems with the digestive system, urinary tract, blood vessels and heart. Some people have mild symptoms. But for others, diabetic neuropathy can be quite painful and disabling.[1]

No medical treatment has proven effective in preventing or arresting the disease process. The goal of the management is to prevention of diabetic foot or amputation. In Ayurveda, it can’t be straightforwardly corelated with any disease, but can be analogous with the symptoms of Prameha Upadrava or Madhumeha or Prameha Poorvarupa. Other scattered references are available in text, which are mainly Vata-Pitta dominant. So, treatment which is Vata-Pitta Shamaka should be initiated.

Case Report

Presenting Complaint

A 60-year-old female patient residing in Gujarat, Jamnagar district, belonging to middle economic class reported the Panchakarma outpatient department (OPD) ITRA, Jamnagar, with the chief complaints of tingling sensation and numbness over bilateral lower limbs, pain, burning sensation over bilateral soles for 3 years, chronic constipation, reduced appetite and psychological stress.

History of present illness

Patient was apparently healthy 5 years back. She was detected with diabetes mellitus 5 years ago. From past 3 years patient started complaining of tingling sensation and numbness over bilateral lower limbs, pain sensation over bilateral lower limbs, burning sensation over bilateral soles, generalised weakness, constipation, reduced appetite for which she consulted and took allopathy medicine but had not noticed any relief. Later, with Ayurveda treatment she had relief. Later, the complaints again aggravated from past 2 months, and hence patient got admitted for better management in ITRA Panchakarma hospital, Jamnagar.

Past medical history

She was under medication of Type 2 Diabetes mellitus and multi vitamins. Patient had previously consulted a private hospital 1 year back (details of medications were not available) where she has not noticed any relief. Later took Ayurveda treatment and felt temporary relief.

Personal history

Appetite: reduced

Bowel: irregular, Hard stool, non-satisfactory once/day

Micturition: regular 4-5times/day, 1-2 times/night

Sleep: Disturbed

Addiction: 3-4 cups tea/day

Habits: outside food weekly thrice

General examination

On physical examination, appearance was moderately built.

Complexion: whitish

B.P.: 130/90mmhg

Pulse: 78/min

Respiratory rate: 18/min

Temperature: Afebrile

Systemic examination

CVS: S1S2 heard, no murmurs

CNS: conscious & oriented to time, place & person

RS: NVBS heard, no added sounds

The investigations like haematology, urology analysis were normal, Vitamin B12 level was normal, biochemistry analysis as Fasting Blood sugar and Post prandial Blood sugar were 267mg/dl and 163mg/dl respectively.

Diagnostic Criteria

Known case of Type 2 Diabetes mellitus along with clinical presentation of Diabetic peripheral neuropathy: Tingling sensation, pricking type of pain, burning sensation over bilateral lower limbs, generalised weakness present, impairment of any one: Vibration perception threshold, hot threshold test, cold threshold test, monofilament test.


Assessment Criteria

Modified Toronto clinical neuropathy score (mTCNS), Vibration and thermal threshold test by Neuropathy analyser Biothesiometer, Monofilament test., Fasting and Post prandial Blood sugar level.

Treatment Given

(on-going mediations of Diabetes mellitus ty-pe 2 were allow to continue during treatment)

Nitya Virechana with Castor oil and Cow milk, Utsadana with Triphala-Nimba Churna with Nimba Taila, Parisheka with Dashamoola Ksheera Kashaya for 15 days.

DaysTreatment given - Nitya Virechana with Castor oil and Milk (As per Agni and Koshtha of patient)Observation
Day 1Dose - 20ml
Time - 7:15am
Vega - 01
Udarshoola, Shirogaurav
Day 2Dose - 20ml
Time - 7:15am
Vega - 01
Udarshoola, Shirogaurav
Day 3Dose - 20ml
Time - 7:15am
Vega - 02
Udarshoola, Shirogaurav
Day 4Dose - 30ml
Time - 7:15am
Vega - 03
Vatanulomana, Laghuta
Day 5Dose - 30ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta
Day 6Dose - 50ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta
Day 7Dose - 50ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta
Day 8Dose - 50ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta
Day 9Dose - 50ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta
Day 10Dose - 50ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta
Day 11Dose - 50ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta
Day 12Dose - 50ml
Time - 7:15am
Vega - 02
Vatanulomana, Laghuta, Agnideepti
Day 13Dose-50ml
Time- 7:15am
Vega-03
Vatanulomana, Laghuta, Agnideepti
Day 14Dose - 50ml
Time - 7:15am
Vega - 03
Vatanulomana, Laghuta, Agnideepti
Day 15Dose - 50ml
Time - 7:15am
Vega - 03
Vatanulomana, Laghuta, Agnideepti
DaysTreatment given - Bahirparimarjana Chikitsa (Utsadana with Triphala Nimba Churna with Nimba Taila), (Parisheka with Dashamoolaksheera)Duration: 20-30 minutesObservation
Day 1Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.-
Day 2Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.-
Day 3Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.-
Day 4Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.-
Day 5Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Angamardavta
Day 6Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka Mridugatrata, Angamardavta
Day 7Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Angamardavta, Susnigdhatvaka, Mridugatrata, Angamardavta
Day 8Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani
Day 9Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani
Day 10Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani
Day 11Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani
Day 12Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani
Day 13Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani
Day 14Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani
Day 15Utsadana with Triphala-Nimba Churna with Nimba Taila followed by Parisheka with Dashamoola Ksheera.Susnigdhatvaka, Mridugatrata, Angamardavta, Shooluparam, Vyadhihani

Assessment

Fasting blood sugar (mg/dl)Post prandial blood sugar (mg/dl)
Before treatmentAfter treatmentBefore treatmentAfter treatment
267105163152

Modified Toronto clinical neuropathy score:

Symptoms scores scoreBTATScoring
Pain101= Present
0= Absent
Numbness10
Tingling10
Weakness10
Ataxia00
Upper limb symp11
Reflexes
Knee reflex (Rt.)100=Normal
1= Reduced
2=Absent
Knee reflex (Lt.)10
Ankle reflex (Rt.)10
Ankle reflex (Lt.)10
Sensory Test Score
Pin prick100= Normal
1= Abnormal
Temperature10
Light touch11
Vibration10
Position sense00
Total score132

Neuropathy Analyzer’s readings

4760_01.JPG
Before Treatment

4760_02.JPG
After Treatment

Discussion

The disease Diabetic peripheral neuropathy cannot be straightforwardly corelated with any disease in ayurveda,


but comparable to Lakshana of Poorva Rupa & Upadrava of Prameha/ Madhumeha. & some other scattered references in text. Diabetic peripheral neuropathy symptoms include: Pain at B/L lower limbs, tingling sensation, numbness at B/L L/L., Burning sensation at B/L soles so treatment should be initiated which pacifying Vata & Pitta dosha. In Diabetic neuropathy symptoms incorporate Lancinating pain, Numbness, tingling sensation are indicating association of Vata dosha, as per Ayurvedic classics Any kind of Pain which is always associated with Vata.[2] whereas burning sensation is because of Ushna Guna of Ashayapkarshita Pitta Dosha.[3] Tingling sensation i.e., Harsha is included in Vata Nanatmaja Vyadhi.[4] Here, Chala guna of Vata is responsible for Hasha. Numbness i.e., Supti[5] is a symptom of Snayu, Kandara, Sira Dushti[6] & also it is Vata Nanatmaja Roga. Supti is produced by Sheeta & Chala guna of Vata. Hence drugs & treatment pacifying Vata & Pitta dosha are valuable in treatment of diabetic neuropathy. (For Assessment of Nitya Virechana, Utsadana & Parisheka - Samyakadi lakshana of classical Virechana, Snehana, Swedana were adopted respectively, as it is not validated yet.)

Nitya Virechana

As DPN considered as an Advance stage of Diabetes mellitus, & considered it as Bahudosha Avastha with predominance of Vata Dosha. & for treatment of Vata in text mentioned as Abhyanga, Swedana, Mridu Samsodhana.[7] If Shodhana like Vamana, Virechana if done, it will further aggravate Vata & worsens condition. So, treatment like Vata Shamaka or Brimhana should be initiated. & in Vata Pradhana Vyadhi Mridu Samsodhana is line of treatment & Nitya Virechana is a Mridu samsodhana. So, in this study Eranda Taila & Milk was selected for Nitya Virechana purpose. Virechana with Eranda Taila & cow’s milk is indicated in Vatavyadhi[8] & Vata Rakta Chikitsa Adhyaya,[9] Ratio of 1:2 was taken. Eranda Taila possess Adhobhagdosha Harana (downward expulsion of Doshas), Bhedana, Ushna (hot), Tikshna (sharp) like properties along with ricinolic acid in chemical composition having tendency to active prostaglandin & act as an irritant which produces purgation.[10]

Utsadana

In prameha Tridosha -Vata, Pitta, Kapha and 10 Dushyas (Rasa, Rakta, Mamsa, Meda, Vasa, Majja, Ambu, Lasika, Shukra, Oaj are involved.[11]

So, Ruksha Udvartana is indicated for Aptarpana purpose.[12] Increase Kleda, Meda, and Kapha are the root cause for developing Prameha so to break the Samprapti from the root Udvartana is indicated.[13] Ruksha Udvartana may lead to small complications like small skin abrasions or skin damage or folliculitis, which may difficult to heal for diabetic patient. Numbness is there so patient may not sense it, if complication occurs, so to prevent a complication, Utsadana is advisable as it contains oil. For Utsadana purpose Triphala Churna Nimba Churna & Nimba oil is selected here, because Triphala Churna is Tridosh Shamak specifically Kapha Shamak & Vata Shamak, Nimba Churna & Nimba oil becoming Pitta & Rakta Shamak, helps to break the root pathology of Diabetes.

Parisheka

Acharya have told Vata is associated with Pitta dosha, Drava Sweda is advisable,[14] therefore Dashamoola Kashaya Ksheera Parisheka was used, which is advised in Vata Rakta Chikitsa chapter.[15] It improves the sensory perception of the skin as Vayu dominates the tactile sensory organ located in the skin. the main ingredient of Ksheera Parisheka treatment is Milk, benefits of Ksheera Parisheka are for proper blood circulation in the body as well as lubricating the joints, relieving pain, spasms & stiffness of muscles and joints. As the nerve cells are damaged, it results in loss of sensation of body. Vata is responsible for sensation in our body, so we have to consider the Vata also. Ksheera has properties like Madhura Rasa, Madhura Vipaka, Snigdha Guna, Vata-Pitta Shamaka & Dhatu Vardhaka. & Milk contains all the elements necessary for the growth & nutrition of bones, nerves, muscles & other tissues. It is rich in proteins, Fats, Carbohydrates, Vitamins & Minerals. The drugs used in Dashamoola Kwatha are effective on the basis of Dosha, Dushya & Srotasa involved in the pathogenesis of the disease. So, Combinedly Dashamoola Ksheera Dhara helps in Vata dominant symptoms i.e., reduction of pain, tingling sensation, Numbness as well as burning sensation also.

Conclusion

Diabetic peripheral neuropathy patients had a significant improvement in both Subjective and objective parameters in the present case study. Neither during treatment nor the follow-up period were any un intended effects of therapy observed.


Thus, it can be said that these treatments are effective in managing, but further study including a larger sample size and a longer duration will be required to prove this impact.

Informed consent: Informed consent for the publication of the data was taken from the patient.

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