@article{Spoorthi G Hegde_Jalindar Dhamale_2022, title={A randomized comparative clinical study of Manjistha Ghrita (Rubia Cordifolia Linn.) and Go-Ghrita in the management of Kikkisa (Striae Gravidarum)}, volume={7}, url={https://jaims.in/jaims/article/view/2072}, DOI={10.21760/jaims.7.9.4}, abstractNote={<p>Skin ailments are the third most common disease &nbsp;&nbsp;&nbsp;&nbsp;in developing countries and in modern society it is a subject of sociomedical importance. One such ailment associated with pregnancy is <em>Kikkisa</em> (Striae gravidarum). <em>Kikkisa</em> (Striae gravidarum) is a <em>Garbhini Vyadhi</em> which occurs mostly in <em>Sapta Masa</em> of <em>Garbhini Kala</em> (7<sup>th</sup> month of pregnancy). It is a condition where growing foetus enlarges <em>Garbhashaya</em> which displaces <em>Doshas Vata, Pitta</em> and <em>Kapha</em> upwards, reaches <em>Uras</em> and produces <em>Daha</em> causing <em>Kandu</em> on abdomen, breasts and thighs. Striae gravidarum are seen in 50-90% of pregnant women due to many physiological, metabolic and hormonal changes along with increased stress on connective tissue will lead to breakage of fibers. <em>Manjistha</em> (<em>Rubia cordifolia </em>Linn.) is considered as <em>Raktashodaka</em> and <em>Kushtanuta</em>. Considering the risk factors in pregnancy the current study has been taken up under external application of <em>M</em><em>anjistha</em> in the form of <em>Ghrita</em> over internal usage of <em>Kwatha</em> as mentioned in authentic text. Keeping this in mind a comparative study was conducted to analyze the effect of <em>Manjistha</em> <em>Ghrita</em> and <em>Go</em>-<em>Ghrita</em> on Striae gravidarum.30 subjects after considering the inclusion and exclusion criteria were taken up for the study. Patient’s general and physical examinations were done. On day 0, through inspection if Striae were observed then <em>Manjistha</em> <em>Ghrita</em> and <em>Go-Ghrita</em> were given in alternative manner. Patients were asked to come for follow up on Day 15. The study period was 30 days and on Day 30, patients were examined to check for any changes in Striae. The obtained data were analyzed statistically using Paired T test, UnPaired T test, Wilcoxon test, Mann Witney test, by using SPSS Software. Usage of <em>Manjistha Ghrita</em> gave considerably good results statistically when compared to application of <em>Go-Ghrita</em> as it only helped in reducing the symptoms till the subjects used the medication and there was recurrence of symptoms later.</p&gt;}, number={9}, journal={Journal of Ayurveda and Integrated Medical Sciences}, author={Spoorthi G Hegde and Jalindar Dhamale}, year={2022}, month={Nov.}, pages={31 - 35} }