TY - JOUR AU - Nivedita Rawat, AU - Sharddha Sharma, PY - 2023/04/24 Y2 - 2024/03/29 TI - Role of Ayurvedic Medicinal Plants in Auto-immune disorders and their management JF - Journal of Ayurveda and Integrated Medical Sciences JA - J Ayurveda Integr Med Sci VL - 8 IS - 3 SE - Review Article DO - 10.21760/jaims.8.3.20 UR - https://jaims.in/jaims/article/view/2343 SP - 108 - 115 AB - Auto-immune disease is an abnormal condition in which immune system start producing auto-antibodies against constituents of its own tissues. Under normal circumstances immune system will not destroy self-antigens, but in Auto-immune disease breakdown of mechanisms responsible for self-tolerance and induction of an immune response against component of the self-body tissues. Activation of self- reactive clones of T or B lymphocytes generating humoral or cell mediated response against self-antigen. Worldwide up to 700 million peoples are estimate to be suffering from auto-immune disease. According to Ayurveda cause of auto-immune disease is due to mechanism of aberrant ‘Agni’ and ‘Ama’ production may occur at macro and micro level. That Ama is full of antigen or the molecules which are mimicking the shape and structure of our healthy tissues. Those molecules are intermediary harmful metabolites which are attacked by our immune system to neutralize. That’s how the autoimmune diseases are start. Also, in auto-immune disease different Dhatvagnis are involved and Dhatus and related Shrotas suffer, resulting Dhatukshay, Ojakshay occurs and further multiple Koshtang and there Avayav affected. Ayurvedic principles are specific and provide numerous medicinal plants which have immuno-modulator properties, like Ashwagandha, Amalaki, Guduchi, Pippali, Punarnava, Yashtimadhu, Vidang etc. the present paper deals with various researches done on Ayurvedic medicinal plants in management of Auto immune disease. Detailed description of all these drugs on Auto-immune disease will be mentioned in full paper. ER -