Journal of Ayurveda and Integrated Medical Sciences

Nasha Mukt Bharat Abhiyan: Harnessing Ayurveda, Yoga, and Spirituality for a Healthier India

Jyoti M. Ganer, Umapati C. Baragi — Fri, 23 May 2025 00:00:00 +0530

The Drug-Free India Campaign (Nashamukti Abhiyan) is a transformative initiative aimed at eradicating substance abuse in India. Given the alarming rise in drug addiction, particularly among youth, this movement integrates Ayurveda, Yoga, and Spirituality to offer a holistic path to recovery. Conventional de-addiction treatments often focus on withdrawal symptoms and rehabilitation, but Ayurveda provides a sustainable approach by addressing the root causes of addiction, detoxifying the body, and restoring mental balance. Therapies like Panchakarma, Rasayana (rejuvenation therapy), and Medhya Rasayana (cognitive enhancement) help eliminate toxins, rebuild strength, and improve emotional resilience. Yoga plays a crucial role in recovery, enhancing physical well-being, emotional stability, and self-discipline. Specific yogic practices, such as Pranayama (breathing techniques) and meditation, help addicts regain mental clarity and resist cravings. Additionally, Satvavajaya Chikitsa, a psychological and spiritual therapy in Ayurveda, helps individuals overcome addiction through self-awareness, mental fortitude, and community support. By integrating these ancient healing sciences into the Drug-Free Bharat Abhiyan, a more sustainable and effective model for de-addiction can be established. To ensure long-term success, efforts must include awareness campaigns, government support, community participation, and dedicated rehabilitation centres that combine Ayurvedic and yogic therapies. A drug-free India is achievable, but it demands collective responsibility and action. By embracing Ayurveda’s wisdom, spiritual teachings, and yogic discipline, India can reclaim its purity and offer a healthier future for generations to come.

To evaluate the Safety and Efficacy of Vedistry Amla + Tablets as a supplement for Healthy Hair

Dnyaneshwar Mote, Sandip Mali, Manasi Maurya — Fri, 23 May 2025 00:00:00 +0530

Background: Hair health reflects overall well-being, influenced by nutrition, stress, aging, and environmental factors. Vedistry Amla + Tablets, rich in Vitamin C and antioxidants, promote hair growth, strength, and scalp health by combating oxidative stress and enhancing collagen production. Clinically evaluated, they effectively reduce hair fall, improve texture, and support holistic hair vitality.

Materials and Methods: This phase 3, non-randomized, prospective, open-label clinical trial assessed Vedistry Amla + Tablets' efficacy and safety in individuals aged 18–70 years experiencing hair concerns such as hair fall, thinning, and dullness.

Study Design: The study involved 300 participants who took one tablet twice daily for three months. Hair health outcomes were evaluated using self-reported questionnaires, clinical assessments, and standardized scales measuring hair strength, fall reduction, and scalp health. Significant improvements were observed in hair texture and nourishment. The treatment was well-tolerated, with no major adverse effects, and participants reported enhanced hair health and confidence.

Observation: Participants exhibited a reduction in hair fall (VAS score decreased from 6.2 ± 1.7 to 3.4 ± 1.5, p = 0.001), along with improvements in hair growth, scalp health, texture, strength, shine, and volume. Confidence and self-esteem also improved notably.

Results: Laboratory assessments showed stable parameters, with notable increases in Vitamin D levels (p = 0.04) and antioxidant levels (p = 0.03). The findings confirm Vedistry Amla + Tablets' efficacy in supporting hair health, while being well-tolerated and safe.

Role of Ashwagandadhi Ksheera Paka and its influence on Maternal and Foetal Weight during Pregnancy

Meghashree B, Ramadevi G — Fri, 23 May 2025 00:00:00 +0530

Background: Ashwagandadhi Ksheera Paka, a traditional Ayurvedic preparation, which is rich in protein, is been used for its potential benefits during pregnancy. However, its impact on maternal and foetal weight gain has not been thoroughly studied.

Objective: This study aims to evaluate the effect of Ashwagandadhi Ksheera Paka administration on maternal and foetal weight gain in pregnant women during the 6^th and 7^th month of pregnancy along with the analytical study of Ashwagandadi Ksheerapaka.

Materials and Methods: Twenty pregnant women were given Ashwagandadhi Ksheera Paka for two months i.e., 6^th and 7^th month. Maternal weight gain was monitored every 15^th day, and fetal weight gain was estimated via ultrasound. Observations were recorded to assess the correlation between the administration of the Ksheera Paka and weight changes.

Results: The administration of Ashwagandadhi Ksheera Paka was associated with a statistically significant increase in both maternal and foetal weight over the two-month period. Analytical Study revealed the presence phytochemicals & presence of protein concentration higher in its hydroalcoholic extract.

Conclusion: The findings suggest that Ashwagandadhi Ksheera Paka may contribute positively to maternal and foetal weight gain during pregnancy. Further studies with larger sample sizes are recommended to confirm these results.

A clinical study to evaluate the effect of Nithya Virechana on range of movements of joints in Amavata w.s.r. to Rheumatoid Arthritis

Deeksha Nayaka HV, Manjunath Kanthi, Niranjan Rao — Fri, 23 May 2025 00:00:00 +0530

Background: Amavata (Rheumatoid Arthritis) is a chronic, progressive inflammatory condition that primarily affects the joints, leading to pain, stiffness, swelling, and restricted mobility. It is characterized by the presence of Ama (undigested toxins) and vitiated Vata Dosha, which together contribute to pathological changes similar to Rheumatoid Arthritis (RA) in modern medicine.

Objective: This study aims to evaluate the effect of Nitya Virechana, assess inflammatory markers (ESR, CRP, ASO, RA factor), and measure the range of joint movements in individuals diagnosed with Amavata/Rheumatoid Arthritis.

Methodology: Nitya Virechana, a subtype of Virechana Karma, is described in classical Ayurvedic texts as a therapeutic intervention that facilitates the elimination of morbid Doshas via the Adhomarga. This procedure is not only beneficial in Pitta Nirharana but also effectively eliminates accumulated Ama, a key pathological factor in Amavata. Classical references suggest Nitya Virechana as an integral component in Amavata management. The present clinical study evaluates the efficacy of Nitya Virechana using Gandharvahastadi Eranda Taila in managing Amavata.

Results: Statistically significant improvement was observed across all parameters, with a p-value < 0.001, indicating positive therapeutic outcomes.

Conclusion: Gandharvahastadi Eranda Taila demonstrated significant efficacy in reducing CRP, RA factor, ASO, along with symptomatic relief and improved joint mobility in Rheumatoid Arthritis. The effectiveness of the treatment has been validated through statistical analysis of key clinical parameters.

Cross Sectional Observational Study of Rasa Dhatu Dushti in Known Diabetic Patients of Chronic Kidney Disease (C.K.D.)

Komal Sandesh Gulakari, Ragini Patil — Fri, 23 May 2025 00:00:00 +0530

The rising incidence of CKD in Indian population is likely to pose major problems for healthcare and the economy in future years. In known diabetic patients of CKD, study of Rasa Dhatu Dushti is important for understanding the role of Rasa Dhatu in Samprapti of CKD. Aim is to assess Rasa Dhatu Dushti in known diabetic patients of chronic kidney disease on dialysis. Objectives are to assess Rasa Dhatu Kshaya, Vruddhi Lakshanas as per Vagbhata and Rasa Dhatu Dushti Lakshanas as per Charaka Samhita and analyse their severity as per the stages in known Diabetic patients of CKD on dialysis. Known diabetic patients of CKD on dialysis of age group 30-70 year and both genders were selected from dialysis centre. A Case Record Form was design for incorporating Lakshanas of different types of Rasa Dhatu Dushti. The stage of CKD is calculated on the basis of Sr. creatinine and Blood Urea reports collected from the patients. On the basis of grading of Lakshanas, the subjects are divided into Mild, Moderate and Severe Rasa Dhatu Vruddhi, Kshaya and Dushti Lakshanas. It is observed that Rasa Dhatu Kshaya, Vruddhi and Dushti remain highly prevalent across all CKD stages. More than 50 % of Rasa Kshaya Lakshanas were observed in 71 patients, Rasa Vruddhi Lakshanas in 40 patients and Rasa Dushti lakshanas in 7 patients. On the basis of outcome of observation and discussion, it is concluded that all types of Rasa Dhatu Dushti (predominantly Rasa Kshayatmaka Dushti) in all stages is present in known diabetic patients CKD on dialysis. Treatment of Rasa Dhatu is important to retard the disease progression.

Comparative evaluation of Ayurvedic formulations Dantyadi Lepa and Swarjika Ksharadi Lepa in the management of Fibroadenosis: A Pharmacognostical Study

Sachin Ladak Shedad, Roy Anuradha, Shiv Ji Gupta, Ruchi Chawla, Binay Sen — Fri, 23 May 2025 00:00:00 +0530

The formulations of Dantyadi Lepa and Swarjika Ksharadi Lepa were subjected to advanced analytical techniques to validate their therapeutic potential in managing fibroadenosis. Kshara standardization ensured the physiochemical properties of Mulaka Kshara and Swarjika Kshara met the Ayurvedic Pharmacopoeia of India (API) standards. The alkaline nature of Swarjika Kshara demonstrated apoptosis-inducing properties in abnormal tissue cells, effectively inhibiting fibroadenotic growth. FTIR analysis revealed the presence of diverse functional groups in both formulations. Dantyadi Lepa showed halo compounds, vinyl groups, amines, alcohols, alkyls, phenols, nitro compounds, amides, alkynes, and carboxylic acids, while Swarjika Ksharadi Lepa exhibited alkenes, aromatics, conjugated alkenes, acid halides, and carboxylic acids. These findings provide a detailed chemical profile, aiding in quality control and therapeutic optimisation. SEM-EDS analysis characterized the formulations as mineral-organic composites with a flaky, layered structure resembling clay or silicate minerals. Elemental analysis revealed the presence of carbon, oxygen, Na, Mg, Al, Si, K, and Ca, with niobium suggesting rare mineral inclusion or industrial contamination. HR-LCMS analysis identified bioactive compounds such as flavonoids, triterpenoids, carotenoids, and fatty acids, which exhibit anti-inflammatory, anticancer, and anti-tumour properties. These compounds, known for their lekhana (scraping) action, inhibit tumour growth and promote the breakdown of fibrous tissue. Bitter and pungent compounds interact with molecular receptors in breast tissue, effectively disrupting pathways responsible for lump formation These combined analyses validate the scientific basis of these formulations, ensuring their consistency, safety, and efficacy in managing fibroadenosis and related conditions.

Comparative Analysis of Stress Prevalence among Married and Unmarried Female Doctors: A Comparative cross-sectional study

Mansi, Rakesh Kumar Verma, Ankit Dabas — Tue, 27 May 2025 00:00:00 +0530

This cross-sectional study investigated and compared stress prevalence among married and unmarried female doctors at Ch. Brahm Prakash Ayurved Charak Sansthan, New Delhi, using the Perceived Stress Scale (PSS). The study included 30 female doctors to assess the impact of marital status on stress levels. Results indicated no significant difference in stress levels between married and unmarried groups (p=0.977), suggesting that marital status does not significantly influence perceived stress in this population. Contrary to common assumptions about increased stress for married women balancing career and family, this study highlights the role of other factors such as job demands, social support, and individual coping mechanisms. Notably, a high proportion of doctors aged 26-30 were married, yet stress levels remained similar across marital statuses. Unmarried doctors may experience distinct stressors, including lack of emotional support and societal pressure. The study's findings suggest a complex interplay of factors influencing stress in female doctors, beyond just marital status. Further research is needed to explore the influence of work experience, department-specific demands, and work shifts on stress levels in this population

A Study Protocol for Pharmaceutico-Analytical study of Rajat Sindoor and evaluation of its Anti-Cancer Activity against Leukaemia using HL60 and K562 cell line model

Bhumika N. Mahajan, Vinod M. Ramteke, Raman S. Belge — Tue, 27 May 2025 00:00:00 +0530

Introduction: Leukaemia is a disease of haematological malignancies that result from the abnormal multiplication of developing leukocytes. A patient suffering through leukaemia experiences an aberrant blood cell synthesis, usually involving leukocytes (white blood cells). Leukaemia is categorized into two groups, based on the cell types that are mostly involved: Lymphoid and Myeloid, also based on the disease's natural course: Acute and Chronic. Neoplasms and Vyadhi Arbuda, which is mentioned in the classics of Ayurveda (Charaka Samhita and Sushruta Samhita), are comparable. Rasa Aushadhis have many therapeutic advantages in many chronic health aspects such as CKD, Cardiac conditions, Inflammatory conditions, bleeding disorders, cancers, etc. Rajat Sindoor is one of the effective Rasa Kalpas found no previous work on in-vitro investigation to assess the anti-cancer activity w. s. r. to Leukaemia.

Materials and Methods: Rajat Sindoor will be prepared as per classical reference. The prepared formulation will be assessed with organoleptic characters and physio-chemical parameters. The Experimental study will be carried out according to the OECD guidelines.

Result: The analytical parameters will be assessed to establish pharmaceutical standardization. The experimental study and statistical analysis will be done accordingly.

Discussion: The purpose of the current study is to evaluate Anti-cancer activity of Rajat Sindoor w. s. r. Leukaemia using HL60 and K562 cell line model. A small step to fill the research gap in the treatment aspect of Leukaemia from Ayurvedic point of view will be done. If significant positive results are obtained in this work, then it will be a valuable contribution in the treatment of leukaemia.

Study Protocol for Pharmaceutico-Analytical study and Clinical Evaluation of modified cream form of Sahachara Ghrita on Mukhdushika with special reference to Acne Vulgaris: A Randomized Controlled Trial

Manjusha S. Uikey, Vinod Ramteke, Raman Belge — Wed, 28 May 2025 00:00:00 +0530

Background: Mukhadushika/Acne vulgaris is a common chronic inflammatory condition of the skin. It is a prevalent issue affecting approximately 80% of teenagers and young adults.^[1] Sahachara Ghrita is mentioned in Bhaishajyaratnavali for Mukhadushika.^[2] To address the challenges of applying Sahachara Ghrita, a cream formulation is being developed for easier and more convenient application.^[3]

Aim: To evaluate the pharmaceutico-Analytical study and clinical effect of modified cream form of Sahachara Ghrita on Mukhdushika with special reference to Acne vulgaris.

Materials & Methods: Sahachara Ghrita will be prepared as per classical reference. Modified cream form Sahachara Ghrita will be prepared as per texts. The prepared formulation will be assessed with organoleptic characters and physicochemical parameters. Clinical study will be carried out in 2 groups with modified cream form of Sahachara Ghrita and standard drug Shalmali Kantakadi Lepa respectively. They will be evaluated for their results on Mukhadushika.

Result: The analytical parameters will be assessed to establish pharmaceutical standardization. The result of clinical study will be drawn from the mentioned assessment criteria. Statistical analysis will be done accordingly.

Conclusion: If significant positive results are obtained in this work, then it will be a valuable contribution and evidence that the drug modified cream form Sahachara Ghrita is effective in Mukhadushika.

Pharmaceutico-Analytical Study and Clinical Evaluation of Tiktadi Ghrita Ointment in Kikkisa with special reference to Striae Gravidarum: A Randomized Controlled Trial

Alka G. Khade, Raman S. Belge — Wed, 28 May 2025 00:00:00 +0530

Introduction: Striae gravidarum are formed with extensive stretching and rupture of elastic fibers present in dermis during pregnancy. The prevalence rate of striae gravidarum, varies from 50% to 90% in various studies among pregnant women. Tiktadi Ghrita, a formulation described in Yogaratnakar (Uttarkhand), aids in the treatment of Vrana, promoting wound healing and alleviating skin discoloration. This study aimed to find the effect of this new topical treatment option i.e., Tiktadi Ghrita ointment on Kikkisa in relation to striae gravidarum.

Aim and Objectives: To evaluate the pharmaceutico-analytical study and clinical effect of Tiktadi Ghrita Ointment in Kikkisa with special reference to Striae gravidarum.

Materials and Methods: Tiktadi Ghrita ointment will be prepared as per classical reference. The prepared formulation will be assessed with organoleptic characters and physicochemical parameters. comparative clinical study will be carried out in 2 groups where each group will receive respective drug and will be evaluated for their results on Kikkisa.

Result: The analytical parameters will be assessed to establish pharmaceutical standardization. The result of clinical study will be drawn from the mentioned assessment criteria. Statistical analysis will be done accordingly.

Discussion: If significant positive results are obtained in this work, then it will be a valuable contribution and evidence that the drug Tiktadi Ghrita ointment is equally effective in Striae gravidarum as Karveer Taila.

A Novel Approach to Nasya Karma Selection: An Analogy-Based Framework

Prerak Shah, Dhruti Kagrana — Mon, 02 Jun 2025 00:00:00 +0530

Nasya, a vital therapy in Ayurveda’s Panchakarma, involves the administration of medicated substances through the nasal passage to treat various head, neck, and neurological disorders. Despite its well-documented benefits, the selection of an appropriate Nasya therapy remains largely subjective, lacking a structured decision-making framework. This study introduces a novel analogy-based model - the Nasal Tunnel Model, which conceptualizes the nasal route as a tunnel with one entry and five distinct exits, each corresponding to a different type of Nasya.

The classification is based on four key parameters

Distance covered - How far the medication travels within the nasal and cranial system.
Speed of response - The rapidity and intensity of therapeutic action.
Medication load - The quantity of medicated substance required.
Strength of formulation - The potency and concentration of active ingredients.

By aligning each Nasya type with transportation and law enforcement analogies, this framework simplifies therapy selection, enhancing precision, efficacy, and patient safety. This structured approach offers Ayurveda practitioners a practical tool for choosing the appropriate Nasya therapy based on specific patient needs, making it more accessible for integration into modern clinical practice while preserving traditional wisdom. This analogy provides a practical approach to choosing the right Nasya type for specific conditions, ensuring optimal efficacy and patient safety.

Exploring the Effects of Om Chanting on Cognitive Functions of Individuals: A Narrative Review

Khemard Singh, Archana K, Swathi K V, Sharada Shetty PS, Vinaya Kumar T — Mon, 02 Jun 2025 00:00:00 +0530

Om chanting is a fundamental practice in yoga and meditation, known for its potential cognitive and physiological benefits. This review aims to explore the effects of Om chanting on cognitive functions, particularly memory, attention, and executive function, among healthy individuals. Several studies indicate that Om chanting modulates brain activity, enhances neural connectivity, and improves psychological well-being.^[1,2] By examining existing literature, we highlight the mechanisms through which Om chanting influences cognitive processes, including autonomic nervous system regulation, cerebral blood flow enhancement, and neurochemical modulation.^[3,4]This review provides insights into the therapeutic applications of Om chanting in cognitive health and suggests directions for future research.

Agraya Dravyas: The Foremost Medicinal Substances in Ayurvedic Science

Sakshi Chalotra, Ankita Goyal — Mon, 02 Jun 2025 00:00:00 +0530

Agraya Dravya refers to the most foremost or superior substances in Ayurveda, chosen based on their highest therapeutic potential and nutritional benefits. These substances are classified as the best in their respective categories such as grains, dairy products, medicinal herbs as documented in classical Ayurvedic texts like Charak Samhita and Sushurut Samhita. The concept of Agraya Dravya helps practitioners select the most effective substances for treatment and overall health. This paper explores the significance, classification, and application of Agraya Dravya highlighting its role in maintaining health and treating diseases.

Critical Analysis of Dhamani Sharir

Poonam Sharma, Sunil Kumar — Mon, 02 Jun 2025 00:00:00 +0530

Ayurveda is a science enriched with the knowledge which was developed and discovered by our Acharya for sustaining life. In Sharir Sthana of Bruhattrayee. Sira, Dhamani, Srotas, all the constituents of Sharir are mentioned in detail in their texts and Dhamani being one of them. Dhamani is an integral part of Sharir. Acharya presented varying perspectives on its origin and function, underscoring the need to consolidate these scattered references. As Dhamani Sharir encompasses structural, functional, pathological, and clinical aspects, understanding it more deeply through modern research is essential for clarifying its applied and therapeutic implications. Objective: The objective is to study and analyse the structure and concept of Dhamani described as in Samhitas. Material & methods: data collected of Dhamani Sharir from Bruhatrayee and related commentaries. Reviewing modern Literature and related journal and articles. Review Methods: All the literature related to Dhamani Sharir is reviewed by analysing the different meanings and thoughts of classical as well as contemporary authors. A separate analysis of commentaries on classical texts is done for better understanding. Discussion and Conclusion: The Ayurvedic concept of Dhamani integrates structural and functional perspectives, describing it as dynamic, pulsating channels carrying Rasa and Prana. Conceptually, it embodies wave-like dynamics, resonating with modern physiology's pulse and neural impulses, vital for sustaining life and consciousness.

A Comprehensive Review of Hansapadi (Adiantum lunulatum) - In Classical Texts

Risheecha, Chandan Singh, Pragati Lajurkar, Garima Gocher — Mon, 02 Jun 2025 00:00:00 +0530

Ayurveda is a comprehensive and holistic system that offers a variety of drugs with various beneficial functions. Adiantum lunulatum, commonly referred to as "Maidenhair fern,” is a plant that is widely planted as an ornamental in India. This drug has important ethnobotanical and medicinal uses. This herb grows in an area near a water source and moist place and grows to a height of 1-1.5 feet. Root-brownish, branches- thin, leaves-small, soft with round dentate borders. The plant is described as a fern that grows in a creeping or sub-erect position. Fern is small, rhizomatous glabrous, and smooth. Hansapadi is having Kashaya Rasa, Guru Guna, Sheeta Veerya and Madhura Vipaka. It has been referenced in classical texts for its therapeutic actions such as Kasahara, Shwashara, Vranaropana, Shothahara, and Jwaraghna Karma. Different Nighantu defines synonyms such as Triparni, Keetamata, Padika, Godhapadi, Hansaraj, Raktapadi, etc. This article reviews the complete details of the drug, such as Morphology, Distribution, chemical constituents, Ethno-botanical claims, and Amayika prayoga (therapeutic uses).

Analysis of Asthi Sharir in relation to the different types of Asthi mentioned in Ayurvedic Samhitas

Vikas Mishra, Shyam Sundar Gupta — Tue, 03 Jun 2025 00:00:00 +0530

The ancient scholars of Ayurveda categorized the body's elements into three fundamental components: Dosha, Dhatu, and Mala. According to Acharya Sushruta, a pioneer of Ayurveda, Asthi (bones) are the last structures to deteriorate in the body. The knowledge of Asthi can be traced back to the Vedic period, evolving through various Samhitas over time. Bones serve as the structural core of the body, providing essential support for physiological functions. Classical Ayurvedic texts offer a detailed account of Asthi, including its nomenclature, classification, enumeration, types, fractures (Bhagna), and their treatment. A special focus is given to the types and terminology of bones, analyzed through both classical and modern linguistic perspectives. This study primarily aims to conduct an analytical discussion on the number and classification of Asthi, various types of bones (Asthi Prakaras), and grammatical validation of their nomenclature. As the understanding of bones has evolved from the Pre-Vedic era to the present, concepts, beliefs, methodologies, and applications have undergone significant transformations. However, the terminology and classifications of Asthi and Bhagna (fractures) remain consistent with contemporary knowledge and are elaborately described in ancient texts.

Stanya-Shodhana Mahakashaya - A Potential Solution for Diseases in Breast Feeding Infants - A Review

Sakshi Jain, Kuldeep Kavathiya, Anjana Rita Xalxo, Subash Sahu — Tue, 03 Jun 2025 00:00:00 +0530

Breast milk is referred as Stanya in Ayurveda texts also known as Piyush (nectar/Amrita); justifies totally with its importance for a newborn. Newborns primarily rely on the breast milk for their nutrition. Ayurvedic texts have described qualities of normal breast milk under the heading “Shuddha Stanya”. Emphasis has been given on the aspect of abnormalities of breast milk and their consequences on infants and as well as on mothers in Ayurveda classics. Vitiation in the normal qualities of Stanya is described as Stanya Dushti. To deal with the same, a concept of Stanyashodhan is mentioned in Charak Samhita in the form of group of ten drugs known as Stanyashodhan Mahakashaya. This article involves synthesizing information from various Ayurvedic texts and internet databases like PubMed, PubMed Central Databases, Google Scholar, CrossRef to substantiate the Stanya Shodhan attributes of these herbs. Neonates are highly susceptible to medication errors and adverse drug events due to their fragile physiology, immature organ systems, and limited ability to metabolize and eliminate medications. This problem can be solved if we treat the mother and thus providing treatment to infants through the Shodhita breast milk using Stanyashodhana Mahakashaya.

Heart Rate Variability and Blood Pressure: Insights into Autonomic Regulation and Cardiovascular Health

Lokesh, Devendra Khurana — Tue, 03 Jun 2025 00:00:00 +0530

The autonomic nervous system (ANS) is essential for regulating cardiovascular activity, ensuring homeostasis, and adapting to bodily needs. This review article delves into the complex mechanisms of how the autonomic system influences the cardiovascular framework, emphasizing the interplay between the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS). The SNS is responsible for increasing heart rate, enhancing the heart's contractile strength, and constricting blood vessels, while the PNS promotes relaxation by lowering heart rate and encouraging vasodilation. Maintaining an appropriate balance between these two systems is vital for cardiovascular health, as imbalances can lead to issues such as hypertension, heart failure, and arrhythmias. Heart rate variability (HRV) serves as a non-invasive indicator of autonomic function, aiding in the evaluation of autonomic balance and the prediction of cardiovascular risk. An autonomic imbalance, particularly characterized by chronic overactivity of the sympathetic system and diminished parasympathetic influence, is linked to negative cardiovascular effects. The baroreflex mechanism, which plays a pivotal role in blood pressure regulation, is also discussed concerning autonomic dysfunction. Furthermore, the article emphasizes how lifestyle factors can affect autonomic regulation and offers information on therapeutic options, including both pharmacological treatments and non-drug strategies like exercise and stress management. Overall, a comprehensive understanding of autonomic regulation and its significance in cardiovascular health is crucial for the prevention and treatment of cardiovascular diseases.

Pramana: An Ayurvedic examination method

Shaily Jain, Gopal Singh Bithu, Shantanu, Pankaj Marolia, Sunita — Tue, 03 Jun 2025 00:00:00 +0530

In Ayurveda true knowledge is referred as Prama and the means to acquire knowledge are known as Pramana. Pramana Vigyana is defined by Ayurveda as a scientific research tool. Ayurvedic scientific methods are enhanced by these Pramanas, which are useful for diagnosing ailments and patients. Ayurveda uses the term Pareeksha in place of Pramana. Pareeksha establishes an object's reality by thoroughly examine. As stated by Acharya Charak the existent or non-existent of things can be investigated by four Pramana i.e., Aptopadesha, Pratyaksha, Anumana and Yukti. Pramanas play a significant role in accurate diagnosis. The purpose is to investigate the significance of Pramanas as they are described in Ayurvedic literature in relation to disease assessment.

Concept of Gandha in Charaka Samhita

Ashwini Patil, Shreevathsa — Tue, 03 Jun 2025 00:00:00 +0530

Ayurveda which is unique in its origin, observations and documentation of diseases and its treatment has added beauty in understanding the prognosis too. Acharya’s have not left any area untouched related with preventive and curative aspect of diseases. The Sharira Sthana ends with Jatisutriya Adhyaya wherein the measurement of child is told indicating the life span. Seeing the bad signs, one can predict the Ayu, which are elaborated in Indriyasthana. This helps in understanding Chikitsa Sthana wherein treatment related to only Sadhya Rogas are said. Ayurveda classifies disease as mainly two i.e., Sadhya and Asadhya. This classification is very important to know the prognosis of disease rather than diagnosis otherwise it can lead to loss of social respect, money and knowledge of physician. For the proper knowledge of Asadhya Laxanas there is description of Arishtas in Samhita Granthas. The whole Indriyasthana of Charaka Samhita (12 chapters), 5 chapters (28 - 33 ) of Sushruta Samhita Sutrasthana and in 2 chapters (5-6) of Ashtanga Hrudaya Sharira sthana different types of arishtas are clearly mentioned which are helpful to explain the prognosis of a patient. Along with Charaka Samhita, Bhela Samhita, Kashyapa Samhita and Harita Samhita also included Indriya Sthana. A total of 47 factors are mentioned to look into for the prognosis. These are again basically grouped under 2 factors i.e., those signs and symptoms which are lodged in subject and those which are understood by inauspicious signs. Thus, it covers all the Laxanas starting from Pratyaksha Bhavas to Anumanagamya Bhavas. In this article, Gandha which is one among the 47 factors is been explained from Indriya Sthana as well as from other Sthana’s.

An Ayurvedic review on clinical utility of Ghrita w.s.r. to cholesterol

Ayushi Nigam, Rajesh Kumar Sharma, Twinkal Parmar — Tue, 03 Jun 2025 00:00:00 +0530

Introduction: Ghrita, also known as Ghee, is a unique natural product highly valued in Ayurveda for its numerous health benefits. It is considered the best among the four types of Sneha (fats) due to its ability to assimilate the properties of added ingredients without losing its own characteristics. Health Benefits: Ghrita is known for its ability to prevent and treat various illnesses. It is highly digestible and does not negatively impact cholesterol levels. In fact, daily consumption of Goghrita has been shown to reduce cholesterol levels. Ghrita also contains essential vitamins and antioxidants that promote overall health. Clinical Utility: Ghrita plays a significant role in Ayurvedic treatments, particularly in internal oleation. Its lipophilic nature facilitates the absorption and delivery of active ingredients to target organs, enhancing the efficacy of Ayurvedic formulations. Ghrita's unique properties make it an ideal medium for delivering herbal compounds in the treatment of various diseases. Conclusion: Ghrita, or Ghee, is a highly beneficial natural product with significant clinical utility in Ayurveda. Its ability to reduce cholesterol levels and enhance the efficacy of Ayurvedic treatments makes it a valuable addition to one's daily diet. Regular consumption of Ghrita can contribute to overall health and well-being.

Exploring the Anti-cancer Potential of Amrutham Ghrita: A Review

Unnati Shrimal, Revathy, Sandip Patil — Tue, 03 Jun 2025 00:00:00 +0530

Cancer, a leading cause of mortality worldwide, is largely attributed to modern lifestyles and environmental toxins. Current treatment options, such as chemotherapy and radiotherapy, are expensive and associated with adverse effects. In the context of Ayurveda, the concept of management of Dushivisha (i.e., cumulative toxicity) offers a promising approach to cancer management. This review focuses on Amrutham Ghrita, a classical Ayurvedic formulation, and its potential anticancer properties. Our analysis of various research papers reveals that the constituents of Amrutham Ghrita, exhibit immunomodulatory, antioxidant, and works against complications arises due to chemotherapy. The results suggest that Amrutham Ghrita may be a novel, cost-effective, and safe adjuvant therapy for management caused by complications aroused due to chemotherapy. This review provides a foundation for future research in this area highlighting the potential of Ayurvedic medicine in addressing the global burden of cancer.

A critical review on effects of Rasayana in Musculoskletal Disorders w.s.r. to Rasna and Guduchi

Rahul H, Lakshmi O. S. — Tue, 03 Jun 2025 00:00:00 +0530

Musculoskeletal degenerative conditions such as osteoarthritis, rheumatoid arthritis etc are common diseases that lead to significant morbidity, reduced quality of life and also economic burden. In the management of these conditions includes pharmacological and non-pharmacological interventions. There are standard descriptions on the Rasayana effect of Guduchi and Rasna in Musculoskeletal degenerative conditions. A concise summary of the article, outlining the focus on the role of Guduchi and Rasna in treating musculoskeletal degenerative conditions, such as osteoarthritis and rheumatoid arthritis. Ayurvedic and modern references were studied and made a review on that. Also, several studies on the drugs were mentioned as supportive evidence for the same. Findings were recorded. Both drugs have shown promising results in clinical studies, with evidence suggesting that their combined use may help in reducing pain, improving joint function, and slowing the progression of musculoskeletal degeneration. The article further explores the pharmacological mechanisms underlying their therapeutic effects, potential synergistic benefits, for musculoskeletal health. Here briefly mention the medicinal properties of both herbs, their known benefits, and the need for further scientific exploration of their effects.

Conceptual Study of Shleshaka Kapha w.s.r. to Synovial Fluid

Yamini Kumari Jain, Chetan Ram Meghwal, Kishori Lal Sharma — Tue, 03 Jun 2025 00:00:00 +0530

Tridosha is the foundation of both health and illness in Ayurveda. Functions including strength, stability, lubrication, intelligence, and so forth are attributed to Kapha Dosha. Shleshaka Kapha, which lubricates joints and promotes fluid movements in an equilibrium state, is found in Sandhi Pradesh. Stiffness and discomfort may result from vitiated conditions. From a modern standpoint, it can be thought of as synovial fluid. Synovial joints in the body contain a fluid composed of hyaluronan, collagenase, lubricin, proteinase, prostaglandins, and other components. Its primary roles are to lubricate joints, support articular cartilage, and facilitate nutrient diffusion. The composition and quantity of synovial fluid can alter due to trauma, inflammation, and various pathological conditions. Both Shleshaka Kapha and synovial fluid share similarities in lubrication, nourishment, shock absorption, viscosity, stability, and immune function. This article aims to explore the concept of Shleshaka Kapha through the lens of modern physiology, particularly in relation to synovial fluid.

Yoga Mudras and Physiological Benefits: A Narrative Review of Their Role in Cardiopulmonary Function

Sachin Ahlawat, Archana K, Anuprita Shetty, Vijay Sharma, Vinaya Kumar T — Tue, 03 Jun 2025 00:00:00 +0530

Yoga Mudras, specific hand gestures used in conjunction with pranayama and meditation, are believed to influence physiological functions, particularly those related to the circulatory and respiratory systems. This narrative review explores the impact of mudras on heart rate, blood pressure, and lung function, integrating traditional yogic wisdom with scientific findings. Studies suggest that certain mudras enhance blood circulation, stabilize autonomic nervous system responses, and improve oxygen saturation levels. Evidence also indicates that mudras, when practiced regularly, can aid in stress reduction, contributing to better cardiovascular health. Additionally, research on pranayama with mudras highlights its role in improving peak expiratory flow rate (PEFR) and respiratory efficiency. Although direct studies on mudras are limited, findings from broader Yoga-based interventions support their potential benefits in cardiopulmonary function. This review underscores the need for further high-quality research to establish mudras as a complementary approach in cardiovascular and respiratory health management.

Exploring the medicinal value of Shigru and Madhushigru: An Insights from Nighantu

Abhishek Gabani, Suman Singh, Hemal Dodiya — Thu, 05 Jun 2025 00:00:00 +0530

Background: Shigru and Madhushigru are very important drugs described in various classical text of Ayurveda. It is mainly indicated in Vidradhi, Shotha, Shoola, etc. Materials and Methods: All the available Ayurvedic Nighantu were referred for the collection of data regarding Shigru and Madhushigru. Observation and Result: The different synonyms of Shigru like Harita Shaka, Tikta Gandha, Shobhanjana, Mulaka Parni etc. and Madhushigru like Raktashigru, Sinhakesari, Raktapushpa, Murangi were observed. Properties of Shigru and Madhushigru like Tikta, Katu Rasa, Ushna Veerya, Katu Vipaka, Kaphavatahara Karma and actions of Shigru like Chakshushya, Grahi, Rochana, etc. and specifically Madhushigru Deepana and Sara action were described in different Nighantu. Discussion: The collection of various information of the Shigru and Madhushigru from 27 Nighantu and compare its variations by their synonyms, properties and actions. Conclusion: The present analysis shows that different types of synonyms, properties and functions described in different periods of Ayurvedic Nighantu can be used to identify and validate medicinal plants. Shigru and Madhushigru possess various pharmacological actions and can play an important role in the treatment of Shoola, Gulma, Vidradhi, Shotha, etc. diseases.

Virudha Ahara - The Ayurvedic Insight into Incompatible Food Combinations

Harsh Bhardwaj, Swapnil Saini, Pooja Sharma, Ajay Shukla, Kashish — Thu, 05 Jun 2025 00:00:00 +0530

Food is the fundamental requirement for the human survival. Ayurveda described the Trividha Upasthambha (sub-pillars), including Ayurveda Ahara (food) being one of the most important for a healthy lifestyle. Ayurveda emphasizes the importance of eating a well-balanced diet. Virudha Ahara (Incompatible Diet) is a diet that disrupts the body's elemental balance, digestion, metabolism (Agni), and homeostasis leading to the accumulation of Ama (toxins). Consuming two incompatible food items together or adhering to a specific type of diet can result in toxicity, this is referred to as Virudha Ahara (incompatible diet). Virudha Ahara can be caused by consuming food in the inappropriate dose, time of day or season. The article discusses the modern perspectives on Samskara Virudha, Veerya Virudha and so on. These perspectives contain incompatible dietary items that can be harmful to a person's health. Ayurvedic literature describes food incompatibility as Gara Visha. This term refers to a substance's toxic effects that become apparent over time. This article focussed on unhealthy food habits that speed up the catabolic process in our bodies.

Scientific Evaluation of Ayurvedic Guggul Formulations: Therapeutic Applications, Pharmacodynamics and Pharmacokinetic Considerations

Vikas Prajapati, Neha Panesar, Nitin, Abhilash PR — Thu, 05 Jun 2025 00:00:00 +0530

Guggul, the oleo-gum resin derived from Commiphora mukul, is a cornerstone of Ayurvedic medicine known for its diverse therapeutic effects. Classical texts document several Guggul formulations - collectively termed Guggul Kalpans - which are customized by combining Guggul with other botanicals to target specific physiological derangements. This article critically reviews the different Guggul Kalpans, their active constituents, and the clinical scenarios in which they have been applied. An emphasis is placed on pharmacokinetic attributes such as absorption, distribution, metabolism, and excretion (ADME) of key compounds like guggulsterones, Active Constituents and Pharmacodynamics. The increasing synergy between traditional wisdom and modern research offers novel insights into potential integrative approaches for managing dyslipidemia, inflammatory disorders, and metabolic syndrome.

The Ayurveda Way - Holistic Geriatric Care for A Healthy Old Age

Rajat Sinha, Jayashree KS — Thu, 05 Jun 2025 00:00:00 +0530

Aging is an inevitable and progressive biological process that affects the physical, mental, and emotional well-being of an individual. Ayurveda, the ancient science of life, provides a holistic approach to geriatric care, focusing on maintaining health, preventing age-related disorders, and promoting longevity. The concept of Jara (aging) is primarily associated with Vata Dosha aggravation, leading to degenerative changes in the body. Dravyaguna Vijnana (Ayurvedic pharmacology) plays a crucial role in geriatric care by utilizing various Rasayana (rejuvenate) herbs and formulations that enhance strength, immunity, cognitive function, and overall vitality. Ayurvedic interventions, including Medhya Rasayana (nootropic herbs), Balya and Brimhana Dravyas (strength-promoting substances), and age-specific dietary regimens, are effective in preventing and managing common geriatric disorders such as Sandhivata (osteoarthritis), Smriti Hani (memory loss), Pandu Roga (anemia), and Jatharagni Mandya (digestive weakness). Along with herbal medicine, therapies like Panchakarma, Abhyanga (oil massage), Swedana (herbal fomentation), and Shirodhara play a significant role in promoting physical and mental well-being in old age. This article explores the role of Dravyaguna in holistic geriatric care, highlighting Ayurvedic pharmacological principles, therapeutic herbs, and formulations that support healthy aging and longevity.

Global Scenario of AYUSH and Insight into Ayurved Concept in Diabetes

Shakuntala Nagar, Dinesh Chandra Sharma, Madhu Parihar — Thu, 05 Jun 2025 00:00:00 +0530

1987 the ‘Alma–Ata’ declaration by WHO stated the evaluation and promotion of traditional medicines. A department called Department of “Indian System of Medicine” was created in March 2003 with a focus for development of traditional system of medicine. Today the globalization process of Ayurved has reached many nations due to the efforts of AYUSH ministry, especially in the Covid-19 pandemic situations. The global Ayurvedic market is estimated to be worth $14.4 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of 27.2% from 2024 to 2030. Ayurved described Diabetes Mellitus (DM) as Madhumeha. This ancient evidence-based system of medicine enumerated various herbs and formulations for its management, which needs scientific validations. Prameha which is described as the ‘Pre-Diabetic’. These two traditional systems, Ayurved and Unani, emphasize that the first and foremost principle of prevention as well as the treatment of any Diabetes.

Female Development Across Ages: An Ayurvedic Review with Contemporary Correlations

Pravesh Tomar, Sudip Kumar Lal, Samiksha Rawat, Nidhi Palariya — Thu, 05 Jun 2025 00:00:00 +0530

Background: The age classification system employed in Ayurveda for females offers a methodical way to comprehend physical, physiological, and social transitions across life stages. Texts such as the Charaka Samhita, Harita Samhita, and Parasara Smṛti categorise female development according to mental maturity, reproductive milestones, and dosha predominance. Aim and Objectives: This study focuses on the Ayurvedic classification of female age and contrasts it with contemporary developmental models, such as Erikson's psychosocial phases, Freud's psychosexual theory and Tanner's puberty classification. The goal is to integrate contemporary and traditional perspectives to provide a holistic understanding of female development. Methods: This study methodically gathers information from traditional Ayurvedic texts, peer-reviewed scientific publications, contemporary textbooks, and reliable websites. Selection is based on authenticity, relevance, and credibility, while extraction involves theme categorization and interpretation. For an in-depth analysis, the synthesis integrates modern scientific insights with ancient Ayurvedic wisdom. Results: Ayurvedic classifications align with contemporary models, indicating that while there are universal patterns of growth and maturity, there are also variations brought about by genetic, environmental, and cultural influences. Discussion & Conclusion: A comprehensive, preventative approach to female health is provided by Ayurvedic classification. By combining Ayurvedic and contemporary frameworks, a holistic model for lifetime well-being can be fostered to improve disease prevention, reproductive management, and personalized healthcare.

Yoga and Mental Health Pharmacotherapy - The Role of Yoga in Reducing the Need for Antidepressants and Anxiolytics - A Narrative Review

Amirabbas Abedini — Thu, 05 Jun 2025 00:00:00 +0530

However, Yoga is widely regarded as a very old mind body practice with the potential to lead to mental health and wellbeing. In this study, the supplement of Yoga to pharmacotherapy in the management of mental health disorders was investigated. Although no pharmacological interventions still remain the bedrock of treatment for disease such as depression, anxiety or stress related, Yoga has a holistic approach to mitigate neurophysiological and psychological processes. It has been shown in research that Yoga improves neurotransmitter balance, lowers cortisol levels and increases emotional resilience, and thus can be used to enhance pharmacotherapy. In addition to that, practices like pranayama (breath control) and meditation help in the regulation of autonomic nervous system, and thereby creating relaxation and dependency on medication goes down over a period of time. Yoga combined with the standard pharmacotherapy has been shown to be a successful way of integrally adding this into the conventional pharmacotherapy, reducing the side effects of drugs and enhancing the overall treatment outcome. This paper reviews the physiological, psychological, and clinical benefits of yoga based on empirical evidence to establish Yoga as an important part of mental health care. Complemented with pharmacological treatments, Yoga can act as mechanisms that include neuroplasticity enhancement and stress reduction, discussed. Accessibility and patient adherence are also considered barriers to integration. This study thus advocates for a multidimensional treatment approach by suggesting that healthcare professionals consider Yoga as part of mental health care plans. There is a need for future research to standardize protocols for Yoga for specific mental disorders and long-term effects. The findings suggest that yoga may be a complimentary treatment with pharmacotherapy for mental health care and a more holistic approach to the treatment of mental health.

Book Review on Puspayurvedah - A unique contribution of Prof. P.V. Sharma

Shruti Aggarwal, Deepak Pareek, Subash Sahu — Thu, 05 Jun 2025 00:00:00 +0530

"Puspayurvedah" authored by Prof. P.V. Sharma, is a scholarly collection of the use of flowers in the Ayurvedic system of medicine. Despite being a specialized subject, traditional Indian medicine heavily relies on the therapeutic qualities, historical importance, and medicinal qualities of diverse flowers. The author painstakingly catalogs a vast variety of flowers using the botanical features and medicinal properties found in traditional Ayurvedic texts. The book offers academicians and clinicians, a thorough knowledge of traditional uses of flowers. "Puspayurvedah" is not only a useful academic resource but also a useful guide for anyone who wants to use floral remedies in Ayurvedic therapy because of its practical formulations and applications. The book is notable for its comprehensiveness and depth of knowledge.

The Dark Side of Beauty: An Analysis of the Toxic Risks in Cosmetics w.s.r. to Dushi Visha

Sushmita Soni, Aaghya Shakyawar, Urmila Shukla, Sunita Rajput — Thu, 05 Jun 2025 00:00:00 +0530

Cosmetics have been used by humans for thousands of years, not only to enhance beauty but also to protect the skin from environmental damage. This shows that caring for the skin has always been an essential part of human life. In recent times, however, the popularity of cosmetic products has grown rapidly. As a result, manufacturers are producing cosmetics in large quantities to meet this rising demand. But this fast-paced production often lacks sufficient attention to safety standards, regulations and quality control. Today, many people use a variety of cosmetic products every day, such as skincare creams, lotions, cleansers, lipsticks, nail polishes, deodorants and more. These products contain harmful ingredients such as Hydroquinone, Parabens, Phthalates and heavy metals like Lead and Arsenic. Prolonged use of these products leads to their accumulation in the body, potentially causing issues like skin irritation, heightened vulnerability to infections, kidney and liver damage, reproductive toxicity and even carcinogenic effects. The skin is an important part of how a person looks. Throughout history and even today, people have cared a lot about outer beauty. Ayurveda is highly valued in beauty care because it offers natural, affordable and effective treatments. In Ayurveda, the concept of "Dushi Visha" (impotent or weak poison) aligns with the toxicity of cosmetics. According to Acharya Sushruta, this type of poison remains in the body for a long time, having been partially neutralized by anti-poisonous treatment. It is described as weak in potency, not causing immediate harm but staying within the body for years, covered by the Kapha Dosha. This article explores the connection between cosmetic chemical toxicity and the Ayurvedic concept of Dushi Visha, offering insight into the health effects of cosmetics and possible solutions from the perspective of ancient toxicology.

A Review Study on Ancient Drug - Mukta

Neha Saharan, Ravneet Kaur Chahal, Abhishek — Thu, 05 Jun 2025 00:00:00 +0530

For thousands of years, Rasa Shastra, also known as Ancient Indian alchemy, has been a part of the medical field that has benefited humanity. In Rasa Shastra, the Ancient Alchemists were particularly interested in Rasa, which means Mercury. Rasa Shastra also studies and prepares different herbo-mineral compounds. And the safe use of Mercurial preparations as medicines from many years, Rasa Shastra also deals with study and the preparation of other herbo-mineral chemicals using various plant drugs and animal origin. One of the drugs, the most widely used in Rasa Shastra is Mukta or Pearl. There are various categories or groups of drugs (Varga) used in Rasa Shastra viz. Maharasas, Uparasas etc. and Mukta is divided under the Ratna (precious treasures) Varga. Mukta, also known as Pearl, is one of the medications that is most frequently utilized in Rasa Shastra. Mukta is a spherical, solid black, dazzling white fish that lives in the water. Its advantageous appearance makes it a common ingredient in apparel, cosmetics, and jewellery. It is created by encircling the center nucleus with many layers of conchiolin and calcium carbonate. Classics of Rasa Shastra state that Madhura, Sheeta, and Laghu belong to Mukta. Additionally, it is frequently used as a potent Pitta Shamaka. Procedures for purification and Pishti are also mentioned in the classics of Rasa Shastra, which makes pearls extremely effective for curing illnesses. In Amlapitta, Jwara and Daha, Mukta is widely used in various forms. The aim of the study is to have a critical review on the conceptual study of Mukta.

A comprehensive review of term Vedana and Vedanasthapana Karma by Padmak (Prunus cerasoides D. Don) in Supti (Sensation Loss)

Ashashri T. Shinde, Sanjay R. Talamale, Madhuri Pachaghare — Thu, 05 Jun 2025 00:00:00 +0530

The term ‘Vedana’ (Samvedo Vedana) is pain, stimuli or sensation with synonym Ruja, Peeda, Dukh, Shool and it is a subjective feeling. The strength of pain varies from person to person, period to period, and site to site. Pain/Vedana, predominantly caused by Vatadosha and it is a pathological symptom. There is confusion between some terms that are related to Pain/Vedana, stimuli, i.e., Angamarda Prashamanam, Shoolprashamana and Vedanasthapana. The contents of Vedanasthapana Mahakashaya, mentioned in Charaka Samhita, revealed outstanding abilities to alleviate pain, regardless of its cause. This paper aims to scrutinize all the aspects of term Vedana, Vedanasthapana karma and conditions where this Karma is benefited which display valuable insights into the multifaceted mechanisms through which pain/Vedana can be effectively established in Supti (sensation less/loss) conditions by one of the drugs of Vedanasthapan Mahakashaya Padmak.

Role of Khadira-Triphaladi Kashaya in the management of Plaque Psoriasis: A Review

Krishna Sharma, Vishal Nandlal Prajapati, Rakesh Kumar Nagar — Thu, 05 Jun 2025 00:00:00 +0530

Background: Globally, the prevalence of psoriasis ranges from 0.09% to 11.4%. It is found to be between 1.5% and 5% in the majority of developed nations. In India, its prevalence rate varies between 0.44 and 2.8%. It is an autoimmune noninfectious, chronic, inflammatory skin disorder where altered keratinization of epidermal cell takes place with well-defined erythematous lesion and silvery plaques. In Ayurveda, according to sign and symptoms of psoriasis we can correlate it with Kapha and Pitta dominant Tridoshaja Kustha. Extensive research work has been conducted on psoriasis, yet a cost-effective and palatable cure remains elusive.

Materials and Methoda: The review on effect of Khadira-Triphaladi Kashaya on psoriasis was done by compiling information from classical Ayurveda text, online pediatrics journals, research papers, recommendations and databases like Medline, PubMed etc.

Discussion & Results: All the ingredients of Khadira-Triphaladi Kashaya have the attributes of Kushthaghana (able to cure dermatological afflictions), Dushtavranvishodhana (Cleansing of a vitiated or infected wound), Kandughana (Anti-Pruritic) and have Katu, Tikta and Kashaya Rasa, Laghu, Ruksha Guna, and Ushna Veerya that are helpful in breaking the pathogenesis of Kapha and Pitta dominant Tridoshaja Kustha (~Plaque Psoriasis).

Conclusion: This paper emphasizes the effect of Khadira-Triphaladi Kashaya on plaque psoriasis.

An Ayurvedic approach on Kumkumadi Taila and its role in enhancing Varnya

Pallavi Prakash Pimparkar, Rajshree Mangesh Shirpurkar — Thu, 05 Jun 2025 00:00:00 +0530

Kumkumadi Taila is a well-known Ayurvedic formulation used for enhancing Varnya (complexion and glow). It is a unique blend of herbs processed in oils that help improve skin tone, reduce pigmentation, and provide a youthful glow. The present study explores the classical references, ingredients, and the effect of Kumkumadi Taila on skin health. Kumkumadi Tailam is classical ayurvedic skin oil formulation describe by Vagbhata. It balances the Pitta, act as anti-inflammation and repair damaged tissue of skin. It helps in other Rakta-Pitta skin disorders as well. The formulation has properties like anti-aging, skin nourishment, anti-wrinkle, moisturizing effects or to improve skin texture. Kumkumadi Tailam has properties which alleviate vitiated Vata-Kapha and acts as Rakta Prasadhak, hence Kanti Vardhak. The application of Kumkumadi Taila pacifies Vata and Pitta Dosha, improves Rakta Shodhana (blood purification), and enhances skin texture, making it a holistic skincare solution.

Dashmoola in Stri Roga: A Review on its Therapeutic Benefits

Pallavi Suman, Rinki Sharma, Suneeta Kumari, Aswathi KK, Kiran Bahuguna — Thu, 05 Jun 2025 00:00:00 +0530

Dashmoola is a prominent Ayurvedic formulation that consists of ten medicinal roots, commonly utilized in the treatment of various gynecological issues, collectively referred to as Stri Roga. This review examines the therapeutic advantages of Dashmoola for Stri Roga, highlighting its pharmacological attributes, historical applications, and validation through contemporary scientific research. It offers a thorough analysis of Dashmoola’s influence on menstrual health, pregnancy, postpartum care, and reproductive wellness. The formulation’s botanical components feature herbs known for their significant anti-inflammatory, analgesic, and adaptogenic characteristics. These attributes render Dashmoola useful in addressing conditions such as menstrual irregularities, difficult periods, heavy menstrual bleeding, infertility, pregnancy-related issues, recovery after childbirth, and symptoms associated with menopause. Moreover, its neuroprotective and immune-modulating effects enhance overall women’s health. Phytochemical investigations have identified bioactive compounds within Dashmoola, including alkaloids, flavonoids, saponins, tannins, all of which contribute to its therapeutic impact. Scientific studies corroborate its traditional applications, emphasizing its effectiveness in hormonal regulation, pain alleviation, and tissue healing. The review also covers clinical applications of Dashmoola, mentioning various formulations like Dashmoolarishta, and Dashmoola Kwath, along with their specific advantages. Additionally, it highlights the necessity for further clinical trials to confirm its effectiveness and establish standard dosages. Potential side effects and necessary precautions for safe usage are also reviewed. The findings indicate that Dashmoola holds significant promise as a natural treatment for gynecological disorders and the promotion of reproductive health. Nevertheless, more comprehensive research is essential for its effective integration into contemporary gynecological practices. This review functions as a detailed resource for comprehending the relevance of Dashmoola in women's health and its future possibilities within integrative medicine.

Akalaja Jara (Premature Aging) and the Role of Manasika Bhavas (Mental States) in Ayurveda: A Holistic Perspective

Navjot Singh, Shivani Thakur — Tue, 10 Jun 2025 00:00:00 +0530

Akalaja Jara, or premature aging, is a multifactorial phenomenon influenced by physical and psychological factors. Ayurveda recognizes the vital role of Manasika Bhava (mental states) in modulating Doshic imbalances, especially Vata, and depleting vital energies such as Ojas, Tejas, and Prana. This paper explores the interrelationship between mental states and premature aging, emphasizing emotional well-being and integrative therapeutic approaches that combine Ayurvedic wisdom with modern science.

Integrating Moral Conduct with Holistic Health in Ayurveda

Ashadeep Mahal, Karan Chugh — Tue, 10 Jun 2025 00:00:00 +0530

Sadvritta, a fundamental concept in Ayurveda, refers to ethical and moral conduct essential for maintaining overall health, particularly mental well-being. Health is not a single entity, it is multidimensional which includes physical, mental, social and spiritual aspect of life in equilibrium. Sadvritta is one of the principles of Ayurveda which keeps all the aspects of health in equilibrium. Sadvritta plays a crucial role in emotional stability, stress management and psychological resilience. Sadvritta encompasses Daihika (physical), Vachika (verbal), Manasika (mental), and Samajika (social) ethics, which collectively aid in preventing mental disorders such as stress, anxiety, and depression. This article explores the connection between Ayurvedic ethics and mental health, highlighting classical references and their relevance in modern psychology well- being. By integrating Sadvritta into daily life, individuals can achieve inner harmony, emotional intelligence and a balanced state of mind.

Effectiveness of Ayurveda in Nephrotic Syndrome w.s.r. to Vrikkajanya Sankarya: An Evidence-Based Case Study

Gracy Sokiya, Keerti Benjwal, Monika Giri — Tue, 10 Jun 2025 00:00:00 +0530

As far as Nephrotic Syndrome is considered, it mainly manifests with major protein loss through urine as a cardinal symptom which can be associated with Vrikkajanya Vikara, which is referred to as a type of renal disorder/Vrikka Vikara. A 24-year-old female presented with left lumbar pain, pus in urine, burning micturition, and proteinuria (3+). On the basis of Dosha assessment, Rasayana, Stambhaka, and Mutral Dravyas like Gokhru, Giloy, Chandraprabha Vati, and Ushirasava, including some dietary modifications, were prescribed for two months. Mild improvement was seen in follow ups. This case signifies the importance of early diagnosis and planned ayurvedic interventions in NS to take preventive measures and to keep away from complications and to improve quality of life.

Management of Pakshaghata through Ayurveda - A Case Series

Pallavy Jayakumar, Ambili Krishna — Tue, 10 Jun 2025 00:00:00 +0530

Vata Dosha is considered to be the most important among Tridoshas in Ayurveda. Neither Pitta Dosha nor Kapha Dosha nor the Dhatus nor the Malas can move on their own. They are led by Vata Dosha just like the clouds which are driven by the wind.^[1] Together with the other two Doshas, Vata plays a vital role in the causation of diseases. But there are some diseases where Vata alone gets vitiated and produce disease and they are generally termed as Vatavyadhis.^[2] Pakshaghata is one among them which is characterized by loss of movement or disability of one side of the body. It may be correlated to hemiplegia caused due to cerebrovascular accident or stroke. This article is an attempt to analyse the case reports of five patients affected by Pakshaghata, who were admitted in our hospital IPD and to develop a general treatment protocol considering the site of lesion, Prakruti, age of the patient, chronicity of the disease etc.

Ayurvedic approach in the management of ALS (MND) - A Case Study

Shwetangi Kharjule, Tapas Bhaduri, Subir Kr. Khan, Neha Yadav — Tue, 10 Jun 2025 00:00:00 +0530

Amyotrophic Lateral Sclerosis (ALS) is progressive motor neuron disease (MND) in which nuclei of upper & motor neurons in spinal cord, cranial nerve & motor cortex are involved. ALS also known as Lou Gehrig’s Disease. The illness is relentlessly progressive in nature, leading to death by respiratory paralysis. There is an incidence of 1-3 per100000 & a prevalence of 3-5 per 100000. It exhibits muscle weakness, Fasciculation, Dysphagia, etc. leads to the complications as involvement of pyramidal signs. This disease affects normal rhythm of life ultimately results in the limitations of day-to-day routine. In this case study 50 years old male patient had symptoms of weakness in Lower extremities, Dysphagia, unable to stand without support, slurred speech. He diagnosed with Amyotrophic Lateral Sclerosis in 2022 at SSKM Hospital, Kolkata, West Bengal. He took treatment in various hospitals of Kolkata but he didn’t get any relief. Then he came to our institute in the hope of proper management. The term ALS is not mentioned in our Samhita however we can clinically correlate the sign & symptoms of this disease with Avritta (~Occlusion) Pakshaghat (~Paralysis). After 3 months of treatment, patient was assessed clinically & with the help of ALSFRS -R Score. Before treatment it was 10 which was increased to 30, showing significant improvement also noticed in his various activities.

A Retrospective Case Series on Management of Nidranasha with Yoga Nidra and Padabhyanga

Rajalekshmy PR, Hemant Toshikhane, Aparna Bagul — Tue, 10 Jun 2025 00:00:00 +0530

Sleep is an inevitable factor in day-to-day life. Sleep disturbances reduce the peace of mind and productivity of a person. Many allopathic drugs are available to induce sleep but that all results in various side effects. Yogic interventions are easy to administer and without any adverse effects, hence as an effort towards this, a trial was done at Parul Ayurved Hospital upon the patients of Nidranasha with the practice of Yoga Nidra and Padabhyanga over a period of 30 days. Marked improvement was noted in the sleep parameters of the patients and the discussion of six cases of Nidranasha is done in the case series.

Management of Vipadika through Panchakarma w.s.r. to Palmoplantar Psoriasis: A Case Report

Sheetal G. Lodha, Ruchika S. Karade — Tue, 10 Jun 2025 00:00:00 +0530

Introduction: Palmo-plantar Psoriasis is a non-infectious chronic inflammatory disease of the skin bound to the palm and soles in extent. In Ayurveda, all skin diseases are recounted under a single heading i.e., Kushtha (skin diseases). Palmo-plantar Psoriasis can be co-related with Vipadika (one of the Kshudra Kushtha described in Ayurveda), based on its clinical signs & symptoms. Aim and Objective: To evaluate the effect of Virechana, Raktamokshan, and Snehapana in a Vipadika w.s.r. to palmoplantar psoriasis. Materials and Methods: In the present case, a 50-year-old female patient was diagnosed as a patient of Vipadika (palmoplantar psoriasis) having pruritic rashes on both palm and sole along with bloody and watery discharge from the same. The patient was treated with Shodhana therapy, which included Shodhnartha Snehapana, Virechana, Raktamokshana, and Shamana Aushadhi. Observation and Results: Significant results were observed in the SPI - Simplified Psoriasis Index (SPI score), as well as in itching and associated complaints. Discussion and Conclusion: Panchakarma therapies like Virechana, Raktamokshana, and Snehapana provide effective relief in the case of Vipadika in symptoms like itching, discharge and SPI score.

Ayurvedic management of Cervico-Lumbar Spondylosis (Khalli) - A Case Report

Pavan HR, Shameem Banu, Lohit BA, Lavanya Laxmi — Tue, 10 Jun 2025 00:00:00 +0530

Cervical and lumbar spondylosis are degenerative spinal conditions resulting from age-related wear and tear, leading to pain, stiffness, reduced mobility, and neurological complications. The rising prevalence of spondylosis is attributed to aging, sedentary lifestyles, and occupational hazards, posing diagnostic and therapeutic challenges. In Ayurveda, if there is a involvement of both cervical and lumbar spondylosis is correlated to Khalli, a type of Vatavyadhi. This study aims to evaluate the efficacy of Panchakarma therapy in the management of Khalli through a single-case study of a 43-year-old female patient who presented with low back pain radiating to the right leg and pain in the nape radiating to the right hand. She underwent a comprehensive Panchakarma treatment protocol, including Udvartana, Basti, Abhyanga, Pinda Swedana, Upanaha, and Siravyadha. After one month of treatment, the patient showed a significant reduction in pain and improved quality of life. The findings suggest that Panchakarma therapy offers a promising approach in managing Khalli.

A minimal invasive management of Recurrent Bartholin Cyst by Kshara Karma - A Case Report

Nidhish Kumar S, Anupama V, Chaithra N — Tue, 10 Jun 2025 00:00:00 +0530

When the ducts of the Bartholin glands become blocked. Bartholin cyst is formed, leading to swelling and discomfort in the vaginal region. Though most Bartholin cysts are asymptomatic, they can cause significant pain and complications, especially when infected. This case report discusses the management of a recurrent Bartholin cyst in a 37-year-old female patient with a history of multiple surgeries for the same. The patient presented with swelling, pain, and difficulty in daily activities due to a recurrent cyst on the right labia majora. Previous treatments had included excision and marsupialization, but the cyst recurred multiple times despite medical management. Given the patient's unwillingness to undergo further invasive surgical procedures, an Ayurvedic approach using Pratisaraneeya Kshara Karma was chosen. The treatment involved Bhedana (Incision) and Visravana (Drainage) followed by the application of Palasha Teekshna Kshara. The procedure was minimally invasive, with no complications, and the patient experienced significant relief. No recurrence was noted after six months, suggesting Kshara Karma as a promising alternative to traditional surgery for managing recurrent Bartholin cysts. Further studies are needed to evaluate its long-term effectiveness and cosmetic outcomes.

An Ayurvedic treatment protocol on Temporomandibular Joint Osteoarthritis - A Case Report

Silpa SS, Aiswarya K, Deepa M S — Wed, 11 Jun 2025 00:00:00 +0530

Temporomandibular Joint Osteoarthritis is a degenerative disorder affecting the temporomandibular joint, characterized by progressive cartilage degradation, subchondral bone changes, and inflammation. In Ayurveda, Temporomandibular Joint Osteoarthritis can be correlated with Hanusandhigata Vata. The disease has the symptoms like pain, joint noise, limited range of motion, impaired jaw function. This condition arises due to Asthikshaya in the Hanusandhi, here it is primarily caused by recurrent dislocation of the temporomandibular joint. Here an attempt is made on Temporomandibular joint osteoarthritis with Ayurvedic management. In this clinical study most of the Ayurvedic drugs and procedures used possess Brimhana (nourishing) property. The drugs and procedures used in this study are found to be effective in temporomandibular joint osteoarthritis.

Intervention of Amavata (Rheumatoid Arthritis) through Ayurvedic approach

Suman Bishnoi, Pradeep Kumar Meena — Wed, 11 Jun 2025 00:00:00 +0530

Introduction: Amavata is an Ama Pradoshaja Vikara, caused by Agnimandya, which leads to accumulation of Ama in Shleshmasthana and Prakopa of Vata Dosha. It closely resembles the chronic inflammatory auto immune disorder called Rheumatoid Arthritis. Clinical features ranges from mild inflammation to complete degenerative changes of joint. Prevalence of R.A is approximately 0.8% worldwide and 0.5-0.75% in India. Materials and Methods: A 36 year old female patient came to OPD of Kayachikitsa Dept. with complaint of multiple joint pain, stiffness and swelling particularly affecting the wrists, knees and hands since 8 years but symptoms have exaggerated from last 8-9 months. Diagnostic evaluation confirmed the presence of rheumatoid factor (RF) and CRP was found raised. Conventional treatments, such as DMARDs & NSAIDs were initiated but resulted in only partial symptom relief. Patient was treated with Kshara Basti for 30 days along with oral ayurvedic medicine such as Rasanadi Kwatha, Eranda Sneha, Chitrakadi Vati, Simhanad Guggulu etc. These modalities help in Amapachan, Vatashaman and Srotas Shodhan. Dietary recommendations emphasized warm, easily digestible foods, and the reduction of cold, heavy, and processed items to mitigate Ama formation. Conclusion: The Ayurvedic approach led to significant improvements in the patient's symptoms, including reduced joint pain and stiffness, enhanced mobility, and overall better quality of life. This case study illustrates the potential benefits of integrating Ayurvedic therapies with conventional treatment to manage Amavata effectively. It highlights the importance of a holistic approach in treating chronic autoimmune conditions and encourages further exploration of Ayurvedic practices in contemporary rheumatology.

Effect of Yogasana with Lifestyle Changes in management of Primary Dysmenorrhoea - A Case Study

Ritu Raisinghani, Vikash Katare, Sadhana Aherwar, Mamata Tirankar — Thu, 12 Jun 2025 00:00:00 +0530

Dysmenorrhea undoubtedly one of the most common complain among all gynecological disorders; is a medical condition of pain during menstruation that interferes with daily activities. Menstruation is a normal and natural process that occurs during a woman's reproductive cycle. Pain is an unpleasant feeling that, depending on its degree, location, nature, and length, can have a detrimental impact on the person experiencing it. Menstrual pain is referred to as dysmenorrhea. A substantial number of women claim to suffer mild, moderate, or severe menstrual discomfort. Dysmenorrhea is becoming a major issue because of the sedentary lifestyle and lack of daily physical activity in hectic schedule. Women today face difficulties in their lives, which makes them stressful. This stressful routine results in malnutrition along with physical and psychological burden. This could have an impact on rasa dhatu suffers. Yoga is a holistic approach towards physically and mentally healthy lifestyle. When practiced regularly over a period of time, it can have the desired effects on the body. Therefore, Yogasana in addition to a change in lifestyle can assist women get out of this stressful and unpleasant scenario. Thus, an attempt is made to relieve the women from the condition of primary dysmenorrhoea with lifestyle changes & Yoga. A case study of 3-month has been done to observe the effect of intervention and improvement in primary dysmenorrhea.

Ayurvedic Management of Shwitra (Vitiligo) - A Case Study

Neha Tyagi, Mohan Kumar SS, Naimish Raj Singh, Atal Bihari Trivedi — Thu, 12 Jun 2025 00:00:00 +0530

Skin is the outer most covering of the body and is the largest organ of integumentary system. In human being, skin pigmentation (affected by melanin) varies among population and skin type can range from dry to non-dry and from oily to non-oily. In Ayurveda Bhrajak Pitta is responsible for Prabha. Any impairment in Bhrajak Pitta and Vata cause skin diseases. All skin diseases come under Kushta and Shwitra is one of them. Like other types of Kushta, Shwitra is caused due to vitiation of Tridoshas and Dhatus like Ras, Rakta, Mamsa and Meda.^[1] In Modern system of medicine similar disease is described as Vitiligo. Vitiligo is a chronic auto immune disorder that causes white lesions on skin. This happens when melanocytes are destroyed causing the skin to turn milky white colour.

Holistic Management of Ankylosing Spondylitis through Ayurveda: A Case Study

Neha Yadav, Soumya Panja, Shwetangi Kharjule, Tapas Bhaduri — Thu, 12 Jun 2025 00:00:00 +0530

Ankylosing Spondylitis is a group of spondylarthrosis, chronic autoimmune inflammatory disorder. Primarily it affects axial skeleton and gradually it affects peripheral joint and extra articular structure. Presence of sacroiliitis and structural changes is seen in this disorder. The usual presentation of Ankylosing Spondylitis is morning stiffness which is relieved after exercise or activity. The term “Ankylosing Spondylitis” is not mentioned in our ancient classics but the signs and symptoms can be clinically correlated to Kati Prishta Trik Graha in Ayurveda. Here major symptoms are Stambha and Shula in Kati Pradesh with Vata Kapha Dosha predominance. This was a single case study conducted at I.P.G.A.E&R at SVSP Kolkata. A 45 yrs old female patient, came to the Out Patient Department. complaining of pain and stiffness in Kati Prishta Trik Pradesh. She was diagnosed with Ankylosing Spondylitis and bilateral Sacroiliitis 7 years ago. Management was done according to the principle of Kati Prishta Trik Graha. Treatment plan included Classical Virechana, Erandamuladi Niruha Basti in Kala Yoga followed by Samana Aushadhi. The disease activity was further analysed using BASDAI and ASDAS- CRP score and we got promising results by the treatment without any adverse effects.

Exploring the efficacy of Basti and Sthanika Chikitsa in Ovarian Endometrioma Management: A Case Study

Thu, 12 Jun 2025 00:00:00 +0530

Introduction: Endometriosis, prevalent in 10-12% of women of reproductive age worldwide, is a common gynecological disorder that is increasingly observed in developing countries like India. It involves endometriomas - cystic lesions, often called chocolate cysts, primarily located in the ovaries. Symptoms include chronic pelvic pain, dysmenorrhea, dyspareunia, depression, and infertility. A 32-year-old software engineer presented to SDM Institute of Ayurveda and Hospital, Bengaluru, with a 2-year history of painful menstrual cycles. Investigations revealed left ovarian endometriomas.

Method: Panchakarma Chikitsa was initiated with Ama Pachana, followed by Lekhana Basti and local treatments on an inpatient basis. Shamana Aushada was recommended for continued care after discharge.

Result: Before treatment (April 13, 2023), pelvic ultrasound revealed two endometriotic cysts in the left ovary: 2.5×2.1×2.2 cm (10cc) and 4.5×4.2×4.3 cm (40cc). After Lekhana Basti (April 22, 2023), follow-up ultrasound showed no remaining cysts.

Discussion: Endometriotic cysts, or chocolate cysts, can be managed similarly to Granti (cysts) with Chedana (surgical intervention) as the primary approach. Due to recurrence and financial constraints, the patient chose non-invasive Ayurvedic treatment. Basti and Sthanika Chikitsa with Lekhana and Ropana properties was used for effective management. After treatment, the patient experienced only mild dysmenorrhea and has resumed normal daily activities.

Role of Ayurveda in Chondromalacia Patella Grade IV - A Case Report

Jitendra Chandrakar, Arundhati Mukhedkar, Anup Thakar — Thu, 12 Jun 2025 00:00:00 +0530

Chondromalacia Patellae is a disease in which the hyaline cartilage of patella is softened and easily wears away. It is found in around 37% knee joint affected patients, with just 0.3% of grade IV. Thus, it is a rare outcome. The case presented here is of 46 years old male patient, who came to Panchakarma OPD with complaint of pain at left knee joint and difficulty in walking. The patient had MRI, suggestive of Chondromalacia Patellae Grade IV of left knee joint. It was diagnosed as Janu Sandhi Gata Vata. It was treated with Janu Basti (~oil pool at knee joint) of Murivennadi Taila externally and Matra Basti (~enema with fats) of ghee-oil mixture made of particular drugs, i.e., Jeevaniya and Sandhaniya Maha Kashaya. Significant improvements were observed in subjective and objective parameters, like pain, range of motion and even MRI after the treatment. This case proves that Snehana (~oleation), specifically with Jeevaniya and Sandhaniya drugs is useful in treating chondromalacia, even of grade IV, which is rare and requires surgical intervention.

Efficacy of Ayurvedic Treatment in Managing Cervical Dystonia: A Case Report

Shyam Prasad PS, Manisha Singla — Thu, 12 Jun 2025 00:00:00 +0530

Cervical dystonia (also known as spasmodic torticollis) is a neurological condition that causes involuntary muscle contractions in the neck, leading to abnormal jerky head movements with spasms. These contractions can cause the head to tilt to one side (laterocollis), rotate (rotational torticollis), or move forward (anterocollis) or backward (retrocollis). The condition can be painful and may interfere with everyday activities. Prakupita Vata (aggravated Vata) causes Vata Vyadhi (diseases of vitiated Vata) and treatments such as Snehana (oleation therapy), Swedana (sudation therapy), and Shodhana (internal detoxification) are advised. This case report presents a 62-year-old male with cervical dystonia/ spasmodic torticollis with complaints of progressive neck pain, involuntary movements predominantly in the right shoulder, shoulder and neck spasms, tremors, and abnormal postures of head. Following an Ayurvedic approach the patient experienced significant improvement within two months, with substantial symptom relief by the fourth month. Shodhana Virechan (internal detoxification) in combination with external Panchakarma procedures such as Nasya Karma, Shirodhara, Greeva Basti, Greeva Pichu with Agni Karma and internal medicines including Rasayana (rejuvenation), were administered. Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) was assessed for the outcome of the treatment. The patient showed good improvement in pain, stiffness, tremors, and neck retention time. TWSTRS score reduced from 68.5 to 15 and is presented here as a case study.