E-ISSN:2456-3110

Research Article

Acne Vulgaris

Journal of Ayurveda and Integrated Medical Sciences

2023 Volume 8 Number 12 December
Publisherwww.maharshicharaka.in

A clinical study of Kumkumadi Tailam Nasya in Yuvan Pidaka w.s.r. to Acne Vulgaris

Banerjee S1*, Rashmi R2
DOI:10.21760/jaims.8.12.6

1* Suratna Banerjee, Post Graduate Scholar, Department of Panchakarma, Ramakrishnna Ayurvedic Medical College Hospital and Research Centre, Ramgondanahalli Yelahanka Bengaluru, Karnataka, India.

2 R Rashmi, Professor and HOD, Department of Panchakarma, Ramakrishnna Ayurvedic Medical College Hospital and Research Centre, Ramgondanahalli Yelahanka Bengaluru, Karnataka, India.

Yuvan Pidaka is a common skin disease which generally occurs during adolescence. Acharya Sushruta described Yauvan Pidika, under the heading of Kshudrarogas.[1] It occur due to vitiation of Kapha-Vata Dosha and Rakta Dhatu,[2] producing Shalmalika-Kantaka Sadrusha Pidakas over face. Swabhava[3] (natural status) has also been considered as one of the causative factors. Though the Tarunya-Avastha (adolescent period) is the age for Shukra Pradurbhava (manifestation of Shukra Dhatu) and Sharangadhara has mentioned Vaktre Snigdhata (unctuousness on face) and Pidika (boil) formation on face as Mala (waste product) of Shukra Dhatu.[4] It is correlated with Acne vulgaris[5] a chronic inflammatory disease of Pilosebaceous Unit. Imbalanced hormonal levels also play a key role in Acne vulgaris. According to Acharyas nasal cavity is a door to provide medicinal drugs to the brain, so Nasya drugs act on brain through cavernous sinus. Observing the Sthana-Samshraya and Vyaktasthana of the disease as mentioned by Acharya Sushruta,[6] an erudite physician always treat patients with wounds in places above clavicular region, showing pain and vitiation by Kapha and Vata, selecting Nasya line of treatment. Kumkumadi Tailam has properties which alleviate vitiated Vata-Kapha and acts as Rakta Prasadhak, hence Kanti Vardhak. According to Acharya Sarangadhar,[7] Uttarkhanda 8th chapter in Marsha Nasya Taila is Srestha as Sira is Adhisthan of Kapha, and also stated that Marsha Nasya Taila can be applied in Kapha or Kapha-Vata related Vikaras with Oushad Dravyas.

Keywords: Yauvan Pidika, Kumkumadi Tailam, Marsha Nasya, Acne Vulgaris

Corresponding Author How to Cite this Article To Browse
Suratna Banerjee, Post Graduate Scholar, Department of Panchakarma, Ramakrishnna Ayurvedic Medical College Hospital and Research Centre, Ramgondanahalli Yelahanka Bengaluru, Karnataka, India.
Email:
Banerjee S, Rashmi R, A clinical study of Kumkumadi Tailam Nasya in Yuvan Pidaka w.s.r. to Acne Vulgaris. J Ayu Int Med Sci. 2023;8(12):33-41.
Available From
https://jaims.in/jaims/article/view/2954

Manuscript Received Review Round 1 Review Round 2 Review Round 3 Accepted
2023-10-11 2023-10-18 2023-10-25 2023-11-04 2023-11-19
Conflict of Interest Funding Ethical Approval Plagiarism X-checker Note
None declared. Nil yes 14.62 none

© 2023by Banerjee S, Rashmi Rand Published by Maharshi Charaka Ayurveda Organization. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ unported [CC BY 4.0].

Introduction

The skin is often referred to as the largest body organ and serves as the main protective barrier against damage to internal tissues from trauma, ultraviolet light, temperature, toxins and bacteria. Changes in the skin colour may indicate homeostatic imbalance in thebody. Everyone wants to look his/her face beautiful, clean and attractive.

Acne is a disorder of the pilosebaceous apparatus characterized by comedones, papules, pustules, cysts and scars. Maharshi Charaka said that, ‘the skin is one of the important sense organs in all of five-sense organ’. Acne[8] is a chronic inflammatory disease of pilosebaceous units, characterized by the development of comedones in forms of papules, pustules and less commonly nodules. There are three important factors involved in the pathogenesis of Acne; they are : 1) increased sebum production 2) hyper- keratinization of pilosebaceous ducts 3) Bacterial colonization of the follicle and 4) inflammation.

It could not be incorrect to say that in most cases, the face is the index of the mind and the mirror of the body. This most important and beautiful organ, which is affected by certain anomalies of the adolescent age i.e., 16-30 years. In Present era due to changing life style, changing food habits, increasing pollution & stress factor skin diseases are a very common. Now a day Yauvan-Pidika (Acne) has becomes a biggest problem of the society, because it affects 85% of teenagers. Yauvan-pidika is one of Kshudrarogas[9] which mainly affects the skin of face. It occurs due to imbalance of Kapha, Vata, and Pitta Doshas and Dushya Rakta.In Ayurveda texts there is a group of diseases called Kshudra Roga, which include 44 diseases.

Mukhadushika is a disease that occurs as papules resembling the sprout on the bark of the Shalmali tree (Bombax malabaricum) appearing on the face and adolescents caused by vitiated Kapha, Vata Dosha and Rakta Dhatu together which makes the face ugly and also known as Yuvan-Pidika. As it common in Yuvan Kala so known as Yuvan Pidaka. Yuvan-Pidaka is well explained in Ayurvedic Samhita.According to Acharya Sushruta, the skin diseases which is mentioned under Kshudra Roga occur due to vitiation of Kapha Dosha, Vata Dosha and Rakta Dhatu and producing Shalmalika-Kantaka-Sadrusha Pidakas over face.

The disease Yauvana Pidika occurs due to vitiation of Kapha, Vata and Rakta. Swabhava (natural status) has also been considered as one of the causative factors. Though the Tarunya Avastha (adolescent period) is the age for Shukra Pradurbhava (manifestation of Shukra Dhatu) and Sharangadhara has mentioned Vaktre Snigdhata (unctuousness on face) and Pidika (boil) formation on face as Mala (waste product) of Shukra Dhatu.

Hence, it is a need of hour to take over a study on such a disease, which is affecting most of the adolescents in their personality development period and as it has been redefined towards as chronic disease instead of simple and self-limiting disease.Here in this study, Nasya Karma has been taken even though other line of treatment like Vaman and Rakhtamokshan has been mentioned. There are many researches carried out in different institutions on Mukhadushika or as, where Vaman and Rakta Mokshan as line of treatment were adopted and got satisfactory results.

Observing the Sthana Samshraya and Vyakta Sthana of the disease as said by Acharya Sushruta (in Chikitsa Sthan 1st chapter), an erudite physician always treat patients with wounds in places above clavicular region, showing pain and vitiation by Kapha and Vata, selecting Nasya line of treatment.Kumkumadi Tailam[10] has properties which alleviate vitiated Vata-Kapha-Pitta and acts as Rakta Prasadhak, hence Kanti Vardhak. Marsha Nasya used for rapid action.

As according to Acharyas, Marsha Nasya[11] is a kind of Snaihik or Brimhan Nasya, so it helps in Dhatu Kshaya and Dosh Kshaya, i.e., declaring rejuvenating property, so, Tvak, Skhandha, Griva, Mukha Mandal and Vaskhasah will be Ghana, Uttam and Prasanna, making all Indriya to work properly. The Tailam used is Tila, as a base, whose Karma is Vatahara, Tvacya, Balya, Keshya, Sukrala. According to Acharya Sarangadhar, Uttarkhanda 8th chapter in Marsha Nasya Taila is Srestha as Sira is Adisthan of Kapha, and also stated that Marsha Nasya Taila can be applied in Kapha or Kapha-Vata related Vikaras with Oushad Dravyas.

Aim and Objectives

To evaluate the effect of Kumkumadi Tailam Marsha Nasya in Yauvana Pidaka.



Materials and Methods

Research design

All 30 patients were selected by simple randomized methods for a single study within a single group with Kumkumadi Tailam Marsha Nasya in Hina Matra (as stated by Acharya Vagbhata and Acharya Sharangadhar) 6 drops in each nostrils for 7 days. Before starting the treatment thorough counselling of patient and brief explanation regarding the procedure of Nasya Karma was done and consent was taken.

Dose of Nasya

As there is no specific doses mention in classical regarding Kumkumadi Tailam Nasya,[12] so the doses to be introduced as per generalised rules of Marsha Nasya, where total 6 drops to be given, as Hina Matra of conventional Nasya therapy, depending on Roga Bala and Rogi Bala in each nostril.

Duration of Nasya

For 7 days consecutively

Nasya Karma (Shodhana Therapy)

SNProcedureUsage of drugsDoseDuration
1.Poorva Karma
Sthanika AbhyangaKumkumadi TailamQ.S.Conventional way to be followed as per classical references.
Mridu NadiswedaNadi SwedanaTill Samyak Sweda Lakshana appears
2.Pradhana KarmaAfter Swedan the sweat is to be pat gently with soft towel and after 5 min. Marsha Nasya will be scheduled with Kumkumadi Tailam.6 drops depending on Rogibala and Rogabala, age etc.For 7 days between 7 a.m. to 8 a.m. i.e., Pratyah Kala and Lakshanas would be observed and recorded (conventional way to be followed as per classical references).
3.Paschat KarmaDhumapan with Haridra Varti for 3 times. Kavala and Gandusha was performed.Q.S.Till Samyak Lakshanas appear.

Sample size

A minimum of 30 patients were taken for study.

Inclusion criteria

The cases are selected as per the features mentioned in classics.

  • Patients with-
    • Shalmalikantaka Drusha Pidakas
    • Ruja
    • Ghana Pidakas
    • Medogarbha Pidakas
    • Avastha–Kapha Pradhan Lakshan Grasta Yuvānapiḍakā
  • Age - More than 16 years and less than 50 years.
  • Sex - No discrimination.
  • Race - No Barrier.
  • Religion - No Barrier.
  • Economic status - No Barrier.
  • Patients of acne with comedones, papules, pustules.

Exclusion criteria

1. Patients with other systemic disorders like thyroid dysfunction.
2. Patient is not less than the age of 16 years and not more than 50 years.
3. Patient's acne having inflammatory cysts and nodules.
4. Patients with other skin disorders like Rosacea, Acne fulminans, Acneiform eruptions.
5. In pregnant women and lactating mothers.
6. Vata Pradhan Lakshan Grasta Yuvāna-Piḍakā
7. Occupation induced Acne
8. Patients having Hormonal imbalance like PCOD.
9. Patients which are contraindicated for Nasya Karma.

Criteria For withdrawal

1. Discontinuation of treatment during trial.
2. Development of any complication at any point of time when treatment is continuing period of study.

Diagnostic criteria

a) Shalmali Kantakakara Pidika - The eruption on face which looks like conical shape resembles with Shalmali Kanta.

b) Saruja - The eruptions are painful. The severity may vary from mild to severe.


C) Ghana - The word Ghana means solid, hard or indurated. The eruptions hard and thick. The Pidika is due to vitiated Kapha.

d) Medogarbha - The eruption is expelled with the Meda. It occurs due to obstruction of the Medo Granthi.

e) Yuna Mukhe - This disease usually affects in adults. This word shows the site of origin of Pidika and time of occurrence of the disease i.e., disease occurs in young adults and affects the face.

Associated Symptoms

1) Vedana - due to Vata

2) Kandu - due to Kapha

3) Daha - due to Pitta

4) Srava - due to Kapha

Study duration

Nasya - 7 days

Follow up - 14days

Total duration - 21days

Criteria for assessment of results

Assessment of results

The Subjective and Objective parameters of baseline data to post medication data compared for assessment of the final results. All the results are analyzed statistically for significant unpaired test.

Subjective parameter

Signs and Symptoms of Yuvan Pidaka are considered as:

1. Shalmali Kantaka Drusha Pidaksa,

2. Ruja,

3. Ghana Pidakas,

4. Medogarbha Pidakas

Objective parameter: IGA Scale is selected.

IGA Scale (Investigators Global Assessment scale) as follow:

Imaging - A pelvic ultrasound scan is usually very good at excluding ovarian cysts and tumor on the ovaries and adrenal gland.

0Clear residual hyper pigmentation and erythema may be seen.
1Almost clear, a few scattered comedones and a few small papules.
2Mild easily recognizable less than half the face is involved. Some comedones and some papules and pustules.
3Moderate more than half the face is involved. Many comedones, papules and pustules.
4Moderate more than half the face is involved. Many comedones, papules and pustules.

Investigation

Investigations are carried out on the patients to rule out other systemic disorders as an optional. The following investigations has been indicated :

Blood tests may be performed to monitor safety of treatment:

1. Complete Heamogram

2. Liver function tests

3. Fasting lipids (cholesterol and triglyceride)

Observations and Results

Distribution of Study Sample by Demographical Data.

Table 1: Distribution of patients by Sex

SexNo. of Patients% of Patients
Male930%
Female2170%

Table 2: Distribution of patients by Age group

Age Group (Yrs )No. of Patients% of Patients
16 to 201343.3%
21 to 241545%
25to 3013.3%
30 & above13.3%

Table 3: Distribution of Patients by Marital Status

Marital StatusNo. of Patients% of Patients
Married26.66%
Unmarried2893.33%
Marital StatusNo. of Patients% of Patients
Married26.66%
Unmarried2893.33%
Occupational StatusNo. of Patients% of Patients
Labour00%
Student2583.33%
Executive13.33%
sedentary413.33%

Overall Response for Size of Pidakas

SizeNo. of Patients% of Patients
Good1653.3%
Moderate930%
Poor516.66%

Overall response for Ghanapidakas

ParameterNo. of Patients% of Patients
Not having Ghana Pidaka1033.33%
Good963.33%
Moderate13.33% 
Poor00%

Parameter of Medogarbha Pidakas

ParameterNo.MeanStd. DeviationStd. Error Mean
Medogarbha Pidakas BT300.9331.03280.2667
Medogarbha Pidakas AT300.4670.51640.1333
Medogarbha Pidakas AF300.0670.25820.0667

Overall response of Ruja

RujaNo. of Patients% of Patients
No Ruja BT1550%
Good1550%
Moderate00%
Poor00%

Parameter of IGA Scale

ParameterNo.MeanStd deviationStd. Error Mean
IGA Scale BT301.9330.59360.1533
IGA Scale AT301.6670.89970.2323
IGA Scale AF301.670.90.232

Interpretation

From the above tables, it can be interpretated as Nasya is significant in BT, AT and AF.

Overall response of IGA Scale

IGA ScaleNo. of Patients% of Patients
Good1653.33%
Moderate1446.66%
Poor00%

Out of 30 patients, 16 patients (53.33%) showed Good response. 14 patients (46.66%) showed Moderate response.

Statistical Analysis - Paired t Test

1. In the Parameter Size of Pidakas, results obtained by Nasya Differ highly in BT and AT but are not significant after AF.

2. In the parameter Ganapidaka, results of Nasya differ significantly in BT, AT but they are not significant AF.

3. In the parameter Medogarbha, Nasya differs highly in BT and AT but not significant AF.

4. In the parameter Ruja, the treatment is not significant in BT-AT and BT-AF.

5. In the parameter IGA-Scale, Nasya is significant in AF (as P < 0.05).

Discussion

Total 30 patients were registered for the study and the observation done on those patients as follows:

Sex: In the study, 9 patients (30%) are male and 21 patients (70%) are female. This is shows that the incidence rate of disease is more in females than males which may be due to more and early hormonal changes seen in females than in males.

Age: In the study, there are 15 patients (50%) in age group 21-24, 13 patients (43%) in age group 16- 20,1 patient (3%) in age group 25-30,1 patient (3%) in age group 30 and above. The incidence rate of disease is more between the age group of 16-24(93%) which may be due to their adolescence, personality development period and stress & strain.

Marital status: In the study 2 patients (7%) were married and 28 patients (93%) were unmarried. The incidence rate of disease is more in unmarried group.

Occupation: In the study 25 patients (83%) were students, 1 patient (3%) was executive and 4 patients (13%) were sedentary. The incidence of rate of disease is seen more in students which may be due to adolescence stage, more worried about their outlook, use of more cosmetics which are comedogenic, exposure to sunlight during travel and other activity which will block the pilosebacous ducts, increases the sebum production and produce acne.

Religion: In the study, 22 patients (73%) were Hindu and 8 patients (23%) were Muslim.

Economic status: In the study, 12 patients (40%) were belonging to lower middle class, 16 patients (53%) were belonging to upper middle class and 2 patients (7%) were belonging to rich class. The incidence of rate of disease is more in upper and lower middle class group which may be due to better standard of living, wrong eating habits and increased buying power of cosmetics.


Food habits: In the study, 16 patients (53%) were mixed type, 14 patients (47%) were vegetarian and. Most of them were consuming spicy, Katu, Kashaya Rasa Pradhana Ahara, junk foods which vitiate Rakta.

Chronicity: In the study, 11 patients (37%) were diagnosed as moderate, 10 patients (33%) were diagnosed as mild, and 9 patients (7%) were diagnosed as severe. The maximum time duration of the disease was about 2 years in the study.

Lesion on affected area: In the study, 27 patients (90%) were having localized lesions and 3 patients (10%) were having generalized. Acne is majorly seen on face as the distribution of sebaceous glands is more on face.

As face is the most exposed part of the body, it can easily get afflicted by dust, air, sunlight which further blocks the sebaceous ducts and produces the lesion. So, it can be called as Mukha dooshika that does the dushana of Mukha.

Color of the Pidakas: In the study, 10 patients (33%) were seen with blackish Pidakas, 19 patients (63%) were with reddish Pidakas and 1 patient (4%) was seen with white Pidakas. This may be because of Raktha Dhatu involved in the manifestation of disease. The change in the color of Pidakas may also be because of change in the color of skin of the patient.

Size of Pidakas: In the study, 16 patients (53%) were having the Pidakas between the size 3-4mm, 12 patients (40%) were having the Pidakas of size between 1-2mm, and 2 patients (7%) were having the Pidakas between the size 5-6mm.

The size of Pidakas would vary due to infection, unhygienic maintenance of the skin, squeezing of skin lesion which may aggravate the condition.

Distribution of Pidakas: In the study 29 patients (97%) were having Pidakas on face, 3 patients (10%) were having distribution of Pidakas on upper back, and 1 patient (3%) was having Pidakas on chest. some of patients were having Pidakas on face and upper back. But most of them were having Pidakas on face.

Kostha: In the study, 4 patients (13%) were having Krura Kosta, 14 patients (47%) were having Mrudu Kosta, 12 patients (40%) were having Madhyama Kosta.

Agni: In the study, 1 patient (3%) had Samagni, 16 patients (53%) had Mandagni, 9 patients (30%) had Tikshagni, 4 patients (13%) had Vishmagni. In the study role of state of Agni is insufficient and moreover there is no direct reference regarding mentioning of Mukhadooshika as Amaja Vikara.

Viharaja Hetu: In the study, 19 patients (63%) were having sunlight as Viharaj Hetu, 8 patients (27%) were having cosmetic as Hetu and 3 patients (10%) were having oral contraceptive as Hetu. Here it is may be observed that sunlight is the main cause of Yuvan-Pidaka, which produces sebum in pilosebaceous ducts, blocks the duct and produce open or closed comedones.

Ahara: In the study most of the people were consuming spicy, Katu, Tiktha, Kashaya Rasa Pradhana Ahara and Abhishyadhi Ahara. So, it may lead to Vata-Kapha Dosha vitiation.

Hypothesis

Mukhadooshika is Kapha Vata Pradhana with Raktha as Dushya according to Sushruta Acharya and Meda as Dushya according to Vagbhata Acharya. Because of this Kapha Vriddi the pilosebaceous duct gets obstructed and leads to the formation of comedones, papules, pustules. The ingredient of Kumkumadi Tailam has the properties of Kapha-Vatahara and also Varnya properties. Hence by administering these drugs in the form of Nasya, it will clear the ducts and also does the Varna Prasadana. And other reason for Mukhadooshika is infection by bacteria propioni bacterium acnes. The drugs in this Taila are also having anti-inflammatory effect, thus help in treating Mukhadooshika.

Effect of therapy on subjective parameters

1. Shape of the Pidakas: It mainly refers to the shape of Pidakas, which are conical in shape wider at the base and sharp at the tip similar to that of the thorn of Shalmali In the study all patients presented with Pidakas having vesicular, circumscribed and pebbly white Pidakas. Among them most of the patients were having vesicular shape of Pidakas. In the study it was observed that Nasya has significant result in the parameter Vesicular it may be because of the ingredients having Tikshna effect may have impacted the shape of Pidakas

2. Size of Pidakas: In the parameter Size of Pidakas, Nasya is highly significant after treatment


but there is no change after follow-up.

3. Ghana Pidaka: is mainly the texture of the Pidakas. Most of the patients were having Ghanata and it is mainly because of Kapha Dosha and Medo Dhatu The Ghanata of Pidakas are may be because of blockage of the ducts, so that the fluid gets collected into the duct. In the parameter Ghanapidakas, Nasya is highly significant after.

4. Medogarbha Pidakas: The Pidakas are impregnated with Medas. In the study most of the patients were having Medata. In the Parameter Medogarbha Pidakas, Nasya is highly significant after treatment but there is no change after follow-up.

5. Ruja: Mainly Vata is responsible for pain. In Mukhadooshika, there will be association of Vata and Kapha. In the study many patients complained of pain. Some of the patients complained pain on touch. In the parameter Ruja, Nasya is not significant before treatment, after treatment and after follow up.

Effect of therapy on objective parameters

In the study IGA scale was selected for the assessment of result before treatment, after treatment and after follow up. The mean effect of 30 patients 1.933 which was reduced to 1.667 and after follow up it was reduced to 1.18.

Thus, reduction of mean effect in IGA scale shows it is significant after follow up. In the parameter IGA Scale, treatment is significant (P<0.005) before treatment, after treatment and after follow up.

Effect of therapy on subjective parameters

Among the Subjective parameters, Size of Pidakas, Ghanata of Pidakas, Medata of Pidakas showed highly significant results at P<0.05 level, and in Subjective parameters like Shape of Pidakas (vesicular), showed significant result, And in the parameter Ruja, significant results after treatment.

Effect of therapy

In the study, Sthanika Abhyanga was done with Kumkumadi Taila, which is Varna Prasadkara, Kustagna. And Swedana was done by advising the patient to take steam after boiling the water. In the study after Abhyanga and Sweda many patients felt relaxed, Nirmalat in Drusti, the complexion and smoothness of skin was increased.

Observation on Nasya Karma

Urolaghava

In the study 9 patients (30%) got Urolaghava Lakshana in 1-2 days, 15 patients (50%) attained Urolaghava Lakshana in 3-4 days, 25 patients (83%) attained Urolaghava Lakshana in 5-6 days and 30 patients (100%) attained Samyak Lakshana in 7-8 days. Patients did not attained Samyak Lakshanas in 1-2 days may be because of more vitiated Doshas.

Shirolaghava

In the study 9 patients (30%) got Shirolaghava Lakshana in 1-2 days, 14 patients (47%) attained Shirolaghava Lakshana in 3-4 days, 24 patients (80%) attained Shirolaghava Lakshana in 5-6 days and 29 patients (97%) attained Samyak Lakshana in 7-8 days. Some of the patients complained of Shirashoola at 3-4 days may be because of Apathya follow up by the patient.

Indriya Swachata

In the study, no patient attained Indriya Swchata Lakshana in 1-2 days, 4 patients (13%) attained Samyak Lakshana in 3-4 days,18 patients (60% attained Samyak Lakshana in 5-6 days and 29 patients (97%) attained Samyak Lakshana in 7-8 days.

1 patient in the study complained of burning sensation of eyes after the whole procedure, it may be because of Dhumapana. 1 patient complained of itching after Nasya, it may be because of Matra of Nasya Dravya, so it was reduced in that patient.

Srotovishuddi

In the study no patient attained Sroto Vishuddi Lakshana in 1-2 or 3-4 days. 12 (40%) patients attained Samyak Lakshana in 5-6 days and 30 patients (100%) attained Samyak Lakshana in 7-8 days. Overall it was observed that after Sthanika Abhyanga and Sweda, there was increase in the complexion of skin, the skin became soft and smooth.

Patients felt relaxed and cooling effect on eyes. After Nasya procedure, it was observed that most of the patient felt Kashaya Rasa in the throat and it made them to expel out the Doshas. Hence the nature and Rasa of the Dravyas involved in the Yoga plays an important role. And in Paschat Karma, after Kavala and Dhoomapana, patients felt lightness in


Uras and Shiras.

Overall effect of treatment in 30 patients

Out of 30 patients, 16 patients (53.33%) showed Good response. 14 patients (46.66%) showed Moderate response.

Conclusion

Based on the Conceptual study, Clinical observations and Discussion the following conclusions may be drawn. The incidence rate of disease is more in the age group of 16-24 years (93%) hence it can be called as Yavanapidaka. The disease is named after the site of illness i.e., Mukha is mainly the affected part of the disease, so it is called as Mukhadooshika. In this disease patients have greater impairment in mental health and associated with psychological disturbances like embracement, anxiety. In the study many of the patients had Manasika Lakshanas like Krodha, Ayasa, Shoka, which aggravates Vata Dosha. In the study, sunlight is the main cause for Mukhadooshika. In the study, subjects showed significant result in the Subjective parameters - Shape of Pidakas and Ruja. All the patients ended with Samyak Nasya Lakshanas. There is significant reduction in Size, Ghanata, Medata of Pidakas. There is significant reduction in Ruja.

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