Study the effect of Darun Lepa in Darunaka

Sneha Batakurki; Prashant Bhandi

doi:10.21760/jaims.9.3.8

Study the effect of Darun Lepa in Darunaka

Batakurki S¹, Bhandi P^2*

DOI:10.21760/jaims.9.3.8

¹ Sneha Batakurki, 3rd year BAMS Student, SGV Ayurvedic Medical College Hospital and Research Centre, Bailhongal Dist Belagavi, Karnataka, India.

^2* Prashant Bhandi, Associate Professor Hod, Dept of Sharira Kriya, Sgv Ayurvedic Medical College Hospital and Research Centre, Bailhongal Dist Belagavi, Karnataka, India.

Darunaka is a Kapha Vataja (due to Kapha and Vata) condition featured with itching, dryness, and scaling of skin over the scalp with an itching sensation is considered a cardinal feature. It has become the most common cause of hair fall. Dandruff is a common scalp disorder, the cause may vary among individuals like fungal, bacterial, dry scalp, oil or irritated skin. In this study a cost effective and simple topical application of Lepa using Haritaki Churna, Amra Beeja Churna and Godugdha as a combination has been evaluated in Darunaka.

Keywords: Haritaki (Terminalia chebula), Amra (Mangifera indica), Godugdha (Cow’s milk), Darunaka (Dandruff), Churna (powder), Lepa (Topical application)

Corresponding Author	How to Cite this Article	To Browse
Prashant Bhandi, Associate Professor Hod, Dept of Sharira Kriya, Sgv Ayurvedic Medical College Hospital and Research Centre, Bailhongal Dist Belagavi, Karnataka, India. Email:	Batakurki S, Bhandi P, Study the effect of Darun Lepa in Darunaka. J Ayu Int Med Sci. 2024;9(3):54-57. Available From https://jaims.in/jaims/article/view/3185

Introduction

There are 44 diseases considered as Kshudraroga [minor diseases]. Darunaka is one of 44 minor diseases according to Acharya Sushruta.^[1] Dandruff is a skin condition mainly affecting the scalp and is classified under seborrheic dermatitis.^[2] It is the most common scalp disorder in adolescence and adulthood. It is a Kapha Vataja (due to Kapha and Vata Doshas) condition featured with itching, dryness, and scaling of skin over the scalp region along with shedding off dead tissue from the scalp with an itching sensation is considered a cardinal feature. It has become the most common cause of hair fall. Darun Lepa contains two main ingredients Haritaki and Amra Beeja, Haritaki is Kashaya Pradhana Lavana Varjit Pancha Rasa, Usna

Virya, Madhura Vipaka, Tridosha Hara, Kustha Krimi and Kandu Nashaka. Amrabeeja Kashaya Ruksha, Vata Pitta Shamaka. Godugdha Sheeta Virya, Madhura Vipaka, Vata Pitta Shamaka.

In this study Lepa of Amra, Haritaki, and Godugdha as the combination after one hour followed by hair wash with Luke warm water.^[3]

Objectives of the Study

The current study is to get relief from Darunaka using Haritaki and Amra Beeja Churna in the form of Lepa for topical application on the scalp. To assess the effect of Darun Lepa in Darunaka (Dandruff).

Materials and Methods

Study Design - Single arm clinical study

Source of data

The subjects were selected from OPD and IPD of SGV Ayurvedic Medical College, Hospital and Research Centre, Bailhongal.

Sample size - 10

Inclusion Criteria

1. Diagnosed case of Darunaka between 18 to 60 years.
2. Subjects which are having the Lakshanas of Darunaka.

Exclusion Criteria

1. Patients having head injury
2. Any scalp infections or psoriasis
3. Patients having Darunaka due to other complications
4. Subjects with other systemic diseases like T.B., HIV

Intervention

Application of Darun Lepa over the scalp after one hour followed by hair wash with Luke warm water

Mode of administration: Lepa with Godugdha (Topical application)

Duration: 1 Hour

Duration of Study: 10 days

Follow-up after 10 days of treatment

Assessment Criteria

Subjective Parameters

1. Shira Kandu (Itching on scalp)
2. Twak Sphutana (Cracking of the skin)
3. Keshabhoomi Rukshata (Dryness of scalp)
4. Keshachyuti (Falling of hair)4

Gradings: 0 - Absent, 1 - Occasion, 2 - Moderate, 3 - Severe

Observations and Results

The study was single arm clinical study conducted on 10 subjects, 9 (90%) patients were male and 1 (10%) patient was female, All the subjects were students in occupation, 8 (80%) subjects were Hindu and 2 (20%) were Muslim. 9 (90%) subjects consumed mixed diet while 1 (10%) subject consumed vegetarian diet. 7 (70%) subjects were of Vata Pitta Prakruti while 3 (30%) were of Kapha Pitta Prakruti.

Table 1: Comparison of different treatment times by status of Shira Kandu by Wilcoxon matched pairs test.

Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Friedman's ANOVA
Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Value	p-value
0th	1.00	3.00	2.00	1.00	-	-	-	15.1250	0.0017*
5th	0.00	1.00	1.00	1.00	71.43	2.0225	0.0431*
10th	0.00	1.00	0.00	0.50	85.71	2.0226	0.0431*
20th	0.00	0.00	0.00	0.00	100.00	2.3664	0.0180*

*p<0.05

Significant result in Shira Kandu symptom and p value is 0.0017*

Table 2: Comparison of different treatment times by status of Twak Sphutana by Wilcoxon matched pairs test.

Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Friedman's ANOVA
Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Value	p-value
0th	1.00	3.00	2.00	0.50	-	-	-
5th	0.00	0.00	0.00	0.00	100.00	1.8257	0.0679	12.0000	0.0070*
10th	0.00	0.00	0.00	0.00	100.00	1.8257	0.0679
20th	0.00	0.00	0.00	0.00	100.00	1.8257	0.0679

*p<0.05

Significant result in Twak Sphutana symptom and p value is 0.0070

Table 3: Comparison of different treatment times by status of Keshabhoomi Rukshata by Wilcoxon matched pairs test.

Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Friedman's ANOVA
Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Value	p-value
0th	1.00	2.00	2.00	0.00	-	-	-
5th	0.00	1.00	1.00	0.00	53.85	2.3660	0.0180*	18.9000	0.0003*
10th	0.00	1.00	0.00	0.50	84.62	2.3664	0.0180*
20th	0.00	0.00	0.00	0.00	100.00	2.3664	0.0180*

*p<0.05

Highly Significant result in Keshabhoomi Rukshata symptoms and p value is 0.0003

Table 4: Comparison of different treatment times by status of Keshachyuti by Wilcoxon matched pairs test.

Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Friedman's ANOVA
Times	Min	Max	Median	IQR	of change from 0th to	Z-value	p-value	Value	p-value
0th	1.00	3.00	2.00	1.75	-	-	-
5th	0.00	2.00	1.00	0.00	47.62	2.5202	0.0117*	25.8434	0.0001*
10th	0.00	1.00	1.00	0.00	61.90	2.5205	0.0117*
20th	0.00	0.00	0.00	0.00	100.00	2.8031	0.0051*

*p<0.05

Highly Significant result in Keshachyuti symptoms and p value is 0.0001*

Discussion

Reference of the Daruna Lepa formulation is available in Sharangadhara Samhita in Uttarkhanda.^[4] The cause of Dandruff Varies among Individuals, depending on their susceptibility. It may be caused by Aharaja Nidana, Viharaja Nidana or both.

In Ayurveda all these signs and symptoms are termed as of Darunaka Vyadhi. Kandu is a symptom of vitiated Kaphadosha and it has an important role in the pathogenesis of Darunaka. This is due to the factors like accumulation of Malas on the scalp and the excessive secretion of sweat etc. Keshachyuti is caused by vitiated Pitta in association with Vata.

The hair fall in Darunaka may occur due to lack of Snigdhata because of vitiated Vata, thereby hairs become dull and rough. Highly significant results in these symptoms Keshabhoomi Rukshata (Dryness of scalp) Keshachyuti (Falling of hair) and other symptoms also reduced after the treatment procedure of 10 days.

Probable mode of drug action

As selected drugs are having action on Doshas like Tridoshahara (Haritaki) and Vata Pitta Shamaka (Amra, Godugdha) reduces the vitiated Vata, Pitta and Kapha which further prevents from itching, dryness of scalp and falling of hair. As the drug has anthraquinone type of glycosides and Triterpenoids which are very much responsible for the anti-inflammatory, anti-microbial activity which helps in Reducing the production of sebum and controlling the hair fall by controlling the dry scaly skin.

Conclusion

The prognosis of Darunaka is included in Sadhya stage according to Vagbhata.^[5] This literature review includes pathogenesis, causative factors, and management of Darunaka as per Ayurveda. By this treatment procedure there was relief from signs and symptoms of Darunaka. Significantly reduced symptoms. Patients feeling better after 5 days of treatment have reduced hair fall and dandruff. Before treatment when patients comb their hairs, so many hairs will be on comb after comb, after the 5 days of treatment this has been reduced significantly. Dryness and dandruff significantly reduced, before the treatment when patients touch their head the dandruff will be on hand but after the treatment it has been reduced significantly.

Acknowledgement

This study was carried out with the Financial Support and sponsorship from Advanced Research and Development Department of Rajiv Gandhi University of Health Sciences, Karnataka, Bengaluru. The authors would like to thank for their support.

References

1. Acharya Sushruta, Sushruta Samhita - Kaviraj Kunjalal Bhishagratna, Vol-II, Edition – 2002. Nidana sthana; Kshudra Roga Nidana Adhyaya; Chapter-13, Page No-103, Shloka-34-35.

2. API - Textbook of Medicine – Yash Pal Munjal; vol-1, edition -9-2012, published by- The Association of Physicians of India; Topic – 4 – Eczemas, p.no.- 481.

3. Acharya Sharangadhara, Särangadhara Samhita – Prof. K.R. Srikanta murthy, Uttarkhanda, Vol-Ⅲ, Edition-1997, Varanasi Chaukhambha Orientalia, Lepa murda taila karna purana vidhi; Chapter-11, Page. No-237, Shloka -19.

4. Acharya Sharangadhara, Särangadhara Samhita – Prof. K.R. Srikanta murthy, Uttarkhanda, Vol-Ⅲ, Edition-1997, Varanasi Chaukhambha Orientalia, Lepamurdataila karnapurana vidhi; Chapter-11, Page. No-237, Shloka -19.

5. Acharya Vagbhata – Astanga Hridayam – K.R. Srikantha Murthy; vol -III Uttarasthana, Edition-2002, Varanasi Krishnadas Academy, chapter-23, Siroroga vijnaniya Adhyaya, p.no.-221, sh.no- 1-2.

Manuscript Received	Review Round 1	Review Round 2	Review Round 3	Accepted
2024-01-09	2024-01-19	2024-01-29	2024-02-08	2024-02-16
Conflict of Interest	Funding	Ethical Approval	Plagiarism X-checker	Note
None declared	Nil	Yes	23.89

Research Article

Effect of Darun Lepa

Journal of Ayurveda and Integrated Medical Sciences

Study the effect of Darun Lepa in Darunaka

Batakurki S¹, Bhandi P^2*

Introduction

Objectives of the Study

Materials and Methods

Observations and Results

Discussion

Conclusion

Acknowledgement

References

Research Article

Effect of Darun Lepa

Journal of Ayurveda and Integrated Medical Sciences

Study the effect of Darun Lepa in Darunaka

Batakurki S1, Bhandi P2*

Introduction

Objectives of the Study

Materials and Methods

Observations and Results

Discussion

Conclusion

Acknowledgement

References

Batakurki S¹, Bhandi P^2*