STUDY TO EVALUATE EFFICACY OF VAJRAVATAKMANDURA IN IRON DEFICIENCY ANEMIA IN ADOLESCENT GIRLS - A RANDOMIZED CONTROLLED TRIAL

  • Rashmi Pareek Assistant Professor, Shri Bhanwar Lal Dugar, Ayurveda Vishwa Bharti, Sardarshahar, Rajasthan, India.
  • Nisha Kumari Ojha Assistant Professor, PG Department of Kaumarbhritya, National Institute of Ayurveda, Jaipur, Rajasthan, India.

Abstract

Background: Anemia in adolescent girls possess greatest burden on their health as it leads to poor cognitive development, poor reproductive health and if not treated may lead to intrauterine growth retardation in their developing fetus. The prevalence of anemia among adolescent is 27% in developing country and 6% in developed country. By looking at the magnitude of the problem, an Ayurveda drug Vajravatakmandura has been selected for the study and the present study was undertaken to evaluate the efficacy of the trial drug in iron deficiency anemia in adolescent girls. Material and methods: 100 subjects satisfying inclusion and exclusion criteria were selected and were randomly divided in two groups. In group A, the trial drug Vajravatakmaņdura was administered and in group B, IFA tablets were given for two month of duration with follow up at every fortnight. Result: Both the trial and control groups showed extremely significant result over subjective parameters. Trial drug Vajravatakmaņdura in group A was found more effective over the subjective parameters - weakness, palpitation, pallor and loss of appetite with % gain of 39.77%, 39.39%, 39.17%, 38.09% respectively. Statistical analysis between before and after treatment findings of objective parameters, extremely significant (P<0.0001) improvement was found in both groups in all parameters, except for RBC count in group A, which was significant. No adverse effects were reported during entire period of study by any of the patients in trial group treated with trial drugConclusion: The trial drug “Vajravatakmandura” is effective, safe and palatable for the management of iron deficiency anemia in adolescent girls.

Published
2018-04-12
How to Cite
PAREEK, Rashmi; OJHA, Nisha Kumari. STUDY TO EVALUATE EFFICACY OF VAJRAVATAKMANDURA IN IRON DEFICIENCY ANEMIA IN ADOLESCENT GIRLS - A RANDOMIZED CONTROLLED TRIAL. Journal of Ayurveda and Integrated Medical Sciences (ISSN 2456-3110), http://www.jaims.in/index.php/jaims/pages/view/Citation, v. 3, n. 1, p. 26 - 33, apr. 2018. ISSN 2456-3110. Available at: <http://jaims.in/index.php/jaims/article/view/481>. Date accessed: 16 july 2018. doi: https://doi.org/10.21760/jaims.v3i01.11635.
Section
Original Article