The Buzz Button to your Toothache – Spilanthes acmella : A Review

  • Dr. Soundarya Vishwanathan Senior Lecturer, Bangalore Institute of Dental Sciences, Bangalore, Karnataka, INDIA.
  • Dr. Nandan N Reader, Bangalore Institute of Dental Sciences, Bangalore, Karnataka, INDIA.
  • Dr. Anitha C Reader, Bangalore Institute of Dental Sciences, Bangalore, Karnataka, INDIA.
  • Dr. Manjushree R Senior Lecturer, Bangalore Institute of Dental Sciences, Bangalore, Karnataka, INDIA.
  • Dr. Sunil Raj N Professor and Head, Bangalore Institute of Dental Sciences, Bangalore, Karnataka, INDIA.
Keywords: Anti - toothache plant, Dentistry, medicinal plants, Spilanthes acmella


Spilanthes acmella, commonly known as toothache plant, is an important medicinal plant belonging to family Asteraceae. It has been reported to possess various biological activities like anti-pyretic, antidiuretic, anti-inflammatory, anti-oxidant, immunomodulatory, hepatoprotective, anticancer and antitoothache etc. The bioactive chemical component is spilanthol, an alkamide which is present in roots and all aerial parts of the plant. Spilanthol has high industrial demand for its use in pharmaceutical, cosmetic and toothpaste industry. S.acmella is quickly getting depleted from its natural habitat, because of its wider applications for commercial use.


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Review Article