Effect of Shirish versus Diclofenac Sodium in PostOperative Pain Management - A Randomized Comparative Clinical Trial

Abstract

Introduction: Post-operative pain is physiological pain which is caused due to tissue trauma. Drugs such as NSAIDs (Non Steroidal Anti Inflammatory Drugs) and Opioids are used for post-operative pain management but are associated with their own drawbacks. Shirish has been in use in Ayurvedic practice for analgesia. It is known to relieve pain and can be used to supplement anesthesia and also get rid of adverse effect of modern analgesic drugs. Aims and Objective: To study the comparative effect of Shirish and Diclofenac sodium in post-operative pain management. Materials and Methods: Randomized clinical trial with Group A (Control Group: Tab Diclofenac sodium 50 mg as a single dose) and Group B (Trial Group: Cap Shirish 500 mg as a single dose). Those who had undergone surgeries like hernia, appendicitis operation under spinal anesthesia were selected as per inclusion criteria. Vitals, desirable effect and undesirable effect, total surgical time, the assessment criteria observed and recorded. Results: Cap. Shirish does not show any undesirable or serious ill effects and altered values of vitals as per statistical analysis. As per visual assessment scale, pain felt by Trial group was earlier than control group. Conclusions: Shirish Vati has analgesic property but its analgesic property and pain threshold capacity is lesser than those of Diclofenac Sodium.