Ayurvedic approach to Limb-Girdle Muscular Dystrophies - A Case Study

Abstract

Limb-girdle muscular dystrophies (LGMD) are a group of rare progressive genetic disorders that are characterized by wasting (atrophy) and weakness of the voluntary muscles of the hip and shoulder areas (limb-girdle area). Muscle weakness and atrophy are progressive and may spread to affect other muscles of the body. Many different subtypes have been identified based upon abnormal changes (mutations) of certain genes. The age at onset, severity, and progression of symptoms of these subtypes may vary greatly from case to case, even among individuals in the same family. Some individuals may have a mild, slowly progressive form of the disorders; other may have a rapidly progressive form of the disorder that causes severe disability. As this is a genetic disorder, we can consider it as Adibala Pravritta Vyadhi. In this condition, by considering the symptoms, we can correlate with Mamsadhatu along with Paraspara Avarana of the Udanavritta Vyanavata. To combact with this condition Swedana, Abhyanga and Mamsarasadi Sneha Prayoga is ideal for treatment. In this case study a 34 years female having the characteristic features of this particular condition along with raised CPK level- 51,500 IU/L, for this specific treatment schedule was planned. Along with this Shamanoushadhi have given better improvement in symptomatically as well as drastic changes in elevated CPK levels.