An explorative clinical study to evaluate the combined effect of Nirgundi Taila Nasya and Chopachinyadi Choorna in the management of Hypothyroidism

Abstract

Backgroud: Hypothyroidism is a hypometabolic clinical state, resulting from the reduction of thyroid hormone functions in the body. Prevalence of hypothyroidism in India is around 10.95% and females are more sufferers than males with ratio 6:1. Prevalence of subclinical hypothyroidism is 6 to 8% in women, 3% in men, and annual risk of developing clinical Hypothyroidism is about 4%. By observing the increasing incidence of hypothyroidism, this study was conducted as an attempt for finding better treatment protocol through the heritage of Ayurveda. Objective of the study: To evaluate the combined effect of Nirgundi Taila Nasya and Chopachinyadi Choorna with Shigrupatra Kwatha in the management of hypothyroidism. Materials and Methods: A single group open clinical study with pre-post test design was carried out in Government Ayurveda Medical College and Hospital, Mysuru and through conducting special camps. Data was collected as per the proforma prepared for the purpose of the study.  Nasya Karma with Nirgundi Taila for 7 days, Chopachinyadi Choorna with Shigru Patra Kwatha as Anupana for 60 days were taken as intervention. The data was analysed using descriptive and inferential statistics. Results: The result on TSH value of 30 subjects after the intervention showed statistically non significant result with p value 0.067. Result on Zulewski’s clinical score for hypothyroidism showed statistically highly significant result with p value 0.000. Conclusion: The intervention used in the study was more effective in reducing the symptomatology of Hypothyroidism, than normalizing the TSH value.