Anatomical review of Skin in Immune System as Primary Immune Response

Abstract

The skin immune system comprises a complex network of cells, functioning both in immunity against invading pathogens but also tolerogenic mechanisms to ensure maintenance of immune homeostasis. The Skin is the first barrier to penetration by microbes. The skin not only defends the body by providing a nearly on penetrable barrier but also reinforces this defense with chemical weapons on the surfaces. The immune system is a wonderful collaboration between cells and proteins that work together to providing defense against infection. The skin immune system comprises a complex network of cell functioning immunity to ensure maintenance of immune system. The paper reviews the functional roles of components of immune system in the skin.