Evidence Based Explanation of the Quote “Vishaado Roga Vardhananam”- A Review
Abstract
Acharya Charaka has given a quote as “Vishaado Roga Vardhananam” in “Yajyha Purushiya Adhyaya”. Vishaada is correlated with generalized anxiety disorder and depression. This quotation means that depression is a leading factor in aggravation of any disease. Depression is a common problem which alters quality of life. It is a major cause of burden of disease worldwide. This paper is a collection of various previous researches which focusses on scientific explanation of this quotation. Depression alters the normal activity of hypothalamic-pituitary-adrenal (HPA) axis. Epigenetic mechanism of DNA methylation is associated with depression. Anxiety or depression can cause alteration in normal functioning of metabolic, neurological, immunological and endocrinal activities of the body. Depression can strengthen the risk of development of various cardiac, respiratory and GIT disorders. Stress or high levels of anxiety or depression during pregnancy lead to long term effects in children like cognitive impairment and developmental disorders. Anxiety or both anxiety and depression are the risk factors for conversion of glaucoma suspects to glaucoma sufferers over a period of time. Childhood depression or anxiety alters quality of life and two to five times increases the risk of suicidal attempts in late childhood or adulthood. This gives an approach towards treatment of any disease which must be focussed on both the physical as well as psychological aspects.
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References
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