Experimental evaluation of Chathusama Vati for its Anti-Diarrheal Activity

Abstract

Background: Diarrhea is the condition of having three or more loose or liquid bowel movements per day. The loss of fluids through diarrhea can cause dehydration and electrolyte disturbances such as potassium deficiency or other salt imbalance. According to the World Health Organization, diarrhea affects 3-5 billion people per year worldwide and cause 5 million death per year. It is an important health problem in all age groups and is a major cause of death in socio-economical backward class of people. Aim and Objective: An experimental evaluation of Chathusama Vati for its anti-diarrheal activity. Methods: The experimental study was a three-group experimental study, conducted on 6 different rats on each group. Total 18 healthy albino rats weighing between 150 gm to 200gm will be taken and divided randomly into three groups; Rats were induced diarrhea with castor oil orally. Rats of group 1 will be administered with distilled water served as control group. Group 2 will be administered with Loperamide 5 mg/kg. Group 3 will be administered with Chathusama Vati (Humandose×0.018). Results: In the experimental study the result was showed as the Chathusama Vati has significant action in Diarrhea. Conclusion: From the experimental study the result it was found that Chathusama Vati showed mild ant- diarrheal activity.