Experimental evaluation of Chathusama Vati for its Anti-Diarrheal Activity

  • Revathy L Post Graduate Scholar, Department of Rasa Shastra & Bhaishajya Kalpana, Ramakrishna Ayurvedic Medical College, Yelahanka, Bengaluru, Karnataka, India.
  • Chaitra LV Associate Professor, Department of Rasa Shastra & Bhaishajya Kalpana, Ramakrishna Ayurvedic Medical College, Yelahanka, Bengaluru, Karnataka, India.
Keywords: Atisara, Diarrhea, Chathusama Vati, Anti-diarrheal activity.

Abstract

Background: Diarrhea is the condition of having three or more loose or liquid bowel movements per day. The loss of fluids through diarrhea can cause dehydration and electrolyte disturbances such as potassium deficiency or other salt imbalance. According to the World Health Organization, diarrhea affects 3-5 billion people per year worldwide and cause 5 million death per year. It is an important health problem in all age groups and is a major cause of death in socio-economical backward class of people. Aim and Objective: An experimental evaluation of Chathusama Vati for its anti-diarrheal activity. Methods: The experimental study was a three-group experimental study, conducted on 6 different rats on each group. Total 18 healthy albino rats weighing between 150 gm to 200gm will be taken and divided randomly into three groups; Rats were induced diarrhea with castor oil orally. Rats of group 1 will be administered with distilled water served as control group. Group 2 will be administered with Loperamide 5 mg/kg. Group 3 will be administered with Chathusama Vati (Humandose×0.018). Results: In the experimental study the result was showed as the Chathusama Vati has significant action in Diarrhea. Conclusion: From the experimental study the result it was found that Chathusama Vati showed mild ant- diarrheal activity.

Downloads

Download data is not yet available.

References

Acharya Agnivesha. Charaka Samhita with Deepika Commentary of Chakrapani Datta, edited by Vaidya Trikamji Acharya, Varanasi: Chaukhambha Surbharathi Prakashan, Reprint 2000, Vol.1, Sutrasthana 1/15, Pg.8.

Rama Devi R. Bhaishajya Kalpana. 2nd edition Kottakkal: Perfect Publications; 2004. Pg.17.

Agnivesha, Charaka, Chakrapani Data, Trikamji Yadavji. Charaka Samhita, Sutrasthana.1st edition, Varanasi: Chaukhambha Surabharathi; 2011. Pg.8.

Diarrheal disease: WHO fact sheet https://www.who.int/news-room/fact-sheets/ detail/ diarrheal disease.

Ashish Mishra, Ankit Seth, and Santosh Kumar Maurya, Therapeutic significance and Pharmacological activities of anti diarrheal medicinal plants mention in Ayurveda: Are view, journal of intercultural ethnopharmacology, Jun- Aug 2016; volume5(3):290-07.

S.Shastri, Madava Nidana, Madhukosha With Hindi comm., Chaukhambha Sanskrit Santhana, Varanasi, vol.II,pg.61.

S.Durgalakshmi, Pious Uthara Anu, Ajantha-An Over view On Nidana Panjaka of Atisara (diarrhea), IAMJ, Vol3, August-2015.

P.D.Londhe, P.A. Chavan. Efficacy Of Shunti Kalpa In The Management of Atisara, IJAPR, March 2016, vol-4, issue-3.

Anti-diarrheal medicine: OTC relief for diarrhea – family doctor. Org

https: /familydoctir.org jan 18.2018.

Shri Das Govind, Bhaishajya Ratnavali, Hindi Translation by Shri Shastri Kaviraja Ambika data Ayurveda acharya, Chaukhambha Sanskrit Sansthan, Varanasi; 2005, 7th Chapter, Sloka no – 149&150, Pg234.

How to Cite
Revathy L, & Chaitra LV. (2022). Experimental evaluation of Chathusama Vati for its Anti-Diarrheal Activity. Journal of Ayurveda and Integrated Medical Sciences, 7(9), 70 - 74. Retrieved from https://jaims.in/jaims/article/view/2078
Section
Original Article