Efficacy of Manjisthadi Yoga in Paracetamol induced Hepatotoxicity in Wistar Rat

Abstract

The liver is one of the most essential organs in the body, as it regulates a variety of physiological functions. It plays a role in metabolism, secretion, storage and among other things. It has a high ability for detoxication and the creation of beneficial principles. A nutritious meal is essential for developing tissue and cells, however nowadays people avoid eating healthy meals in favor of fast food to save time and money. This junk food is jam-packed with pollutants like phthalates that are bad for the body, as well as excessive amounts of sugar, salt and trans-fat. Numerous metabolic illnesses and systemic issues like obesity, diabetes and liver disease are caused by them. This type of meal or cuisine is referred to as Viruddha Aahara in Ayurveda. Viruddh Aahara, when consumed in excess, agitates the Doshas at their locations and remains in the body, blocking channels (Strotoavrodha). This block prevents nutrients from reaching the Dhatus (tissue) and many Dhatujanya Vikara develop as a result. As a result, hepatotoxic chemicals' injury to the liver has serious consequences. Toxic substances, excessive alcohol intake, virus infections, medicines such as paracetamol, antibiotics and autoimmune disorders are the main causes of liver damage. Taking the all the above facts in consideration the selection of the study has been done.