Clinical efficacy of Rajanyadi Choornam in Allergic Respiratory Disease in Children

Abstract

Allergic Respiratory Disease (ARD) is a frequent atopic condition manifesting through allergic rhino conjunctivitis and asthma, affecting up to 40% of the population world-wide. Though not viewed as a life-threatening condition, it is also recognized to impose a significant burden to the quality of life of sufferers and their caretakers. It is apparent from epidemiology studies that the Allergic Respiratory Disease in younger children below the age of 5 years is a relatively common problem. Many conventional managements provide only symptomatic relief resulting in recurrence of the disease. At the same time Ayurveda, aims at the elimination of the disease from its root cause rather than providing only a symptomatic relief that may cause recurrence of the condition. Rajanyadi Choornam is one such herbal formulation mentioned in the classics which would enhance the status of digestive fire (Grahani Deepanam Sreshtam) and helps in proper channelization of Vata (Vataanulomana), providing considerable relief to symptoms. A total of 32 children of age group 2-5 years satisfying the inclusion criteria were included in the study. The participants were given Rajanyadi Choornam in a dose of 2.5 gm twice daily with 5 ml of Madhu and Ghritam taken in unequal quantities. The severity of clinical symptoms and blood parameters (serum IgE, AEC) were assessed after 45 days of intervention. For clinical evaluation data regarding the severity of symptoms were collected and laboratory investigations like Serum Total IgE, AEC were done in the children both before and after drug intervention. The results were analysed statistically and reduction of symptoms was statistically significant.