Clinical Evaluation of MINISCAR Cream

Nitin Berde

doi:10.21760/jaims.8.3.3

Nitin Berde M.D. (AYU.), Regn. No. I-23403-A-1, Dhanvantari Clinic, Shop No 1, Sai Om D, Louis Wadi, Thane (w), Mumbai, Maharashtra, India.

DOI: https://doi.org/10.21760/jaims.8.3.3

Keywords: Clinical research; Scar prevention; Herbal extract; Hypertrophic scarring; Drug delivery; Transdermal delivery; Skin; Acne scar, Keloid scar

Abstract

Background: Scars are areas of fibrous tissue that replace normal skin tissue after injury. In Ayurveda several medicines claimed to be beneficial for removing, rather reducing the scar is available. Objective: This clinical study is aimed to evaluate the effects of MINISCAR cream manufactured by Charak Pharma Pvt. Ltd. on skin scars. Method: 60 patients both male female between 18-50 years suffering from scar markings were included in trial. All patients were advised to apply MINISCAR cream once in a day for 30 days. Analysis was done on the basis of pre and post study photograph of the affected area taken along with the date and patient name. Results: There were 44 females and 16 male patients. In 24 patients of acne scar, 54% patients showed significant improvement. In 20 patients of stretch marks, almost 50% patients showed significant improvement. In 6 patients of hypertrophic scars, 66% patients showed significant improvement. While no significant improvement was observed in 2 patients of contracture scar and 8 patients of Keloid scar. Conclusion: Overall with MINISCAR cream almost 45% patient improved exceptionally well, which is certainly a very good outcome. A detailed clinical trial needs to be conducted further to verify the outcomes of the trial.

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References

Skin scarring, A Bayat, D A McGrouther, M W J Ferguson, BMJ 2003; 326 Published 11 January 2003, BMJ 2003;326:88.

Skin repair and scar formation: the central role of TGF-β, Steven R. Beanes, Catherine Dang, Chia Soo and Kang Ting, Published online by Cambridge University Press: 13 February 2004.

Differences in collagen architecture between keloid, hypertrophic scar, normotrophic scar, and normal skin: An objective histopathological analysis, Pauline D. H. M. Verhaegen, MD; Paul P. M. van Zuijlen, MD, PhD ; Noor M. Pennings, MD; Jan van Marle, PhD; Frank B. Niessen, MD, PhD; Chantal M. A. M. van der Horst, MD, PhD, Esther Middelkoop, PhD. Wound Repair and Regeneration, Volume 17, Issue 5, September/October 2009.

Scar Treatment Variations by Skin Type; Marty O. Visscher, PhD, J. Kevin Bailey, MD, David B. Hom, MD; Facial Plastic Surgery Clinic, Volume 22, Issue 3, P453-462, August 2014.