A review on Punarnavadi Kwath : An Ayurvedic polyherbal formulation for Chronic Kidney Disease (CKD)
Abstract
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural abnormalities, or impaired excretory renal function suggestive of a loss of functional nephrons. Most patients with CKD are at risk of accelerated cardiovascular disease and death. Punarnavadi Kwath is a formulation, which contains nine medicinal plants viz. Boerhavia diffusa, Barberis aristate Dc. Curcuma longa, Zingiber officinale Roxb, Terminalia chebula Retz. Tinospora cordifolia (Willd.), Plumbago zeylanica Muell Arg, Clerodendron serratum, Cedrus deodara (Roxb) Loud. These herbs have the potential to treat symptoms of CKD like inflammation and pain other than that, the goal of treatment is to improve kidney function, reduce symptoms and prevent complications. This review paper emphasized on a comprehensive information for each herb of Punarnavadi Kwath because pharmacology, mechanism of actions based on various preclinical studies, safety precautions along with the current research potential of the herb. At the same time, the probable pharmacodynamic action of drugs is drawn to know the imperative for optimal and safe utilization of the herb, are discussed in this review paper.
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