Assessment of efficacy of Amlapittagna Arka in Amlapitta - A Clinical Observational Study

Abstract

Amlapitta indicates a disease characterized by pathological changes in Pitta, one of the predominant Doshas, including Samana Vayu, Pachaka Pitta, and Kledaka Kapha. These changes lead to the aggravation of Tridosha and manifest symptoms such as Avipaka, Klama, Utklesha, Gaurava, Hritkantha Daha, Tiktamlodgara, and Aruchi, among others. Numerous Pittakara and Amapradoshaja Nidanas contribute to its onset, exacerbated by sedentary lifestyles and a lack of adherence to Dinacharya Rutucharya and proper Rasayana practices, ultimately reducing human lifespan. In this clinical research project, subjective parameters were selected to assess the efficacy of Amla Pittagna Arka, sourced from Ravana Samhita Arka Prakashana. Fifteen patients participated in the study, undergoing Kosta Shodhana by Haritakyadi Yoga for three days followed by 21 days of Amla Pittagna Arka administration. Subjective parameters were evaluated every seventh day, with data collected before and after treatment. Statistical analysis by experts revealed significant improvements, with Tikta/Amlodgara reduced by 89.74%, Hritkanta Daha by 90%, Utklesh by 90.48%, Aruchi by 61.54%, Avipaka by 80.00%, Klama by 48.28%, and Gaurava by 48.15%. The trial drug, Amla Pittagna Arka, demonstrated effectiveness particularly in Vata Pittanubandi type of Amla Pitta. Further large-scale research is necessary to validate its efficacy.