An Ayurvedic approach for Non-alcoholic fatty liver associated with Type 2 Diabetes Mellitus: A Case report

  • Bhavya Khatri Post Graduate Scholar, Department of Kayachikitsa, National Institute of Ayurveda, Jaipur, Rajasthan, India.
  • Gaurav Methil Post Graduate Scholar, Department of Kayachikitsa, National Institute of Ayurveda, Jaipur, Rajasthan, India.
  • Harish Bhakuni Associate Professor, Department of Kayachikitsa, National Institute of Ayurveda, Jaipur, Rajasthan, India.
  • Ajay Kumar Sahu Associate Professor, Department of Kayachikitsa, National Institute of Ayurveda, Jaipur, Rajasthan, India.
Keywords: Ayurveda, Non-alcoholic Fatty liver (NAFLD), T2DM, Santarpanotha Vikar

Abstract

Background: The term Non-alcoholic fatty liver (NAFLD) refers to the accumulation of excessive fat inside the liver cells when excessive alcohol use is not present. The presence of both NAFLD and T2DM increases the likelihood of the development of complications of diabetes (including both macro- and micro- vascular complications) as well as augmenting the risk of more severe NAFLD, including cirrhosis, hepatocellular carcinoma and death. Liver illness is also described quite well in Ayurveda. NAFLD may be seen as a Santarpanotha Vikar (illness) bought on by Pittasthan, Raktavahasrotomoola, Kaphmedodusti and Sthanasamsraya in Yakrut (liver). Aim: To evaluate the efficacy of Ayurvedic intervention in NAFLD associate with T2DM. Method and material: In this case report, effect of Ayurveda intervention in grade III fatty liver is reported. Fifty -eight -year-old obese male with grade III fatty liver presented with fatigue, heaviness in abdomen, belching and incomplete bowel evacuation. On examination, there was no significant clinical abnormality except a high body mass index and haematological parameters. The patient was diagnosed sonologically with a grade III fatty liver. Observation and Conclusion: The patient was given Ayurveda treatment for two months. The patient was assessed for improvement in signs and symptoms, haematological parameters, and quality of life. Present case highlights the potential of Ayurveda interventions in managing non-alcoholic fatty liver disease with T2DM.

Downloads

Download data is not yet available.

References

Huang D.Q., El-Serag H.B., Loomba R. Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention. Nat Rev Gastroenterol Hepatol. 2021;18(4):223–238. doi: 10.1038/s41575-020-00381-6.

Sanchez P.P., Bril F., Maximos M., Lomonaco R., Biernacki D., Orsak B. High prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus and normal plasma aminotransferase levels. J Clin Endocrinol Metab. 2015:jc20151966.

Armstrong M.J., Hazlehurst J.M., Parker R., Koushiappi E., Mann J., Khan S. Severe asymptomatic non-alcoholic fatty liver disease in routine diabetes care; a multi-disciplinary team approach to diagnosis and management. QJM. 2014;107:33–41.

Williamson R.M., Price J.F., Hayes P.C., Glancy S., Frier B.M., Johnston G.I. Prevalence and markers of advanced liver disease in type 2 diabetes. QJM. 2012;105:425–432.

https://www.researchgate.net/deref/https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F21497741%2F?_tp=eyJjb250ZXh0Ijp7ImZpcnN0UGFnZSI6InB1YmxpY2F0aW9uIiwicGFnZSI6InB1YmxpY2F0aW9uIn19

https://www.researchgate.net/publication/380131982_The_role_of_Ayurvedic_management_in_non-alcoholic_fatty_liver_disease_NAFLD_a_case_study

Singhal P., Nesari T., Gupta G.S. Efficacy of herbo-mineral compounds and pathya (Ayurvedic dietary regime and physical exercise) in the management of Yakṛt Roga (Non-alcoholic fatty liver disease) Anc Sci Life. 2015;34(4):216–222. doi: 10.4103/0257-7941.160866.

Santosh Pal, A Ramamurthy, Bidhan Mahajon. Arogyavardhini Vati: A theoritical analysis. Journal of Scientific and Innovative Research 2016; 5(6): 225-227.

https://www.wjpmr.com/home/article_abstract/2436

Mitra, S., De, A., & Chowdhury, A. (2019). Epidemiology of non-alcoholic and alcoholic fatty liver diseases. Translational Gastroenterology And Hepatology, 5. Retrieved from https://tgh. amegroups.com/article /view/5499

Chalasani N, Younossi Z, Lavine JE, et al.; American Gastroenterological Association; American Association for the Study of Liver Diseases; American College of Gastroenterology. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 2012; 142: 1592–1609pmid: 22656328

Fernando Bril and Kenneth Cusi Management of Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes: A Call to Action. Diabetes Care 2017 Mar; 40(3): 419-430. https://doi.org/ 10.2337/dc16-1787

Mehta S. R. (2010). Advances in the treatment of nonalcoholic fatty liver disease. Therapeutic advances in endocrinology and metabolism, 1(3), 101–115. https://doi.org/10.1177/204201881 0379587.

CITATION
DOI: 10.21760/jaims.9.6.52
Published: 2024-08-27
How to Cite
Bhavya Khatri, Gaurav Methil, Harish Bhakuni, & Ajay Kumar Sahu. (2024). An Ayurvedic approach for Non-alcoholic fatty liver associated with Type 2 Diabetes Mellitus: A Case report. Journal of Ayurveda and Integrated Medical Sciences, 9(6), 318 - 323. https://doi.org/10.21760/jaims.9.6.52
Section
Case Report