Evaluation of Antifungal Activity of Somaraji Taila Extract & Taila in Dadru Kushta (Tinea Infections) - An Experimental Study

Prashanth Gadgade; Susheel Shetty; Babu Paul

doi:10.21760/jaims.9.8.2

Prashanth Gadgade Final Year Post Graduate Scholar, Department of Kayachikitsa, Alva’s Ayurveda Medical College, Moodabidire, Karnataka, India.
Susheel Shetty Professor & HOD, Post Graduate Department of Kayachikitsa, Alva’s Ayurveda Medical College, Moodabidire, Karnataka, India.
Babu Paul Assistant Professor, Post Graduate Department of Kayachikitsa, Alva’s Ayurveda Medical College, Moodabidire, Karnataka, India.

DOI: https://doi.org/10.21760/jaims.9.8.2

Keywords: Ayurveda, Dadru Kushta, Tinea Infection, Ringworm Infection, Somaraji Taila, Antifungal Activity

Abstract

Dermatophytosis has become a significant health problem affecting children, adolescents, and adults worldwide. In India 5 out of 1000 people suffer from Tinea infections. The present study evaluated the antifungal activity of Somaraji Taila in Tinea (Dermatophytosis) in Invitro & Invivo model. Cultures were brought from MTCC a government body and inoculated in SDA media under aseptic condition. Later it was subjected to microscopic and macroscopic examination to identify the organism. A sensitivity test was done using SDA media by well diffusion method, with 4 different concentrations of Hydro-Methanolic extraction of Somaraji Taila ingredients. After the incubation period, the zone of inhibition was checked and was measured in mm. As the next phase of the study, animal study was also conducted to check antifungal properties & anti dermal toxicity on albino rat skin.

Downloads

Download data is not yet available.

References

Vaidya Jadavaji Trikamji Acharya, Sushruta Samhita, Shareera Sthana, 8th edition, Chapter 4/4, Varanasi; Chawkhambha Orientalia;2005:p355.

Valeria FM, Preve L, Tullio V. Fungi responsible for skin mycoses in Turin (Italy). Mycoses, 1996; 39: 141-50

https://www.researchgate.net/publication/327224680_Study_of_common_dermatoses_in_school_children_of_rural_area_of_Dakshina_Kannada_district_India_a_cross-sectional_study.

Araujo CR, Miranda KC, Fernandes OFL, Soares AJ, Silva MRR. In Vitro susceptibility testing of dermatophytes isolated in Goiania, Brazil, against five antifungal agents by broth microdilution method. J Inst Trop Med., 2009; 51: 9-12.

Aly AA, Omar SA, Zayed SME, Mansour MTM. Use of saponin-containing A triplex nummular to suppress damping of cotton seedling. J Agric Sci., 2000; 25: 7621-31.

Aly MM, Bafiel S. Screening for antimicrobial activity of some medicinal plants in Saudi Arabia. World Conference on Medical and Aromatic, 2008.

Jeyachandran R, Mahesh A. Antimicrobial evaluation of Kigelia Africana (Lam). Res J Microbiol, 2007; 2: 645-9.

Burkill HM. The Useful Plants of West Tropical Africa. Vol. 6 Royal Botanical Gardens, Kew, 2004

G. Prabhakara Rao, Cakradatta of Cakrapanidatta with English translation, edi 2014, Chaukhamba Orientalia, Varanasi, Chikitsa Sangraha Chapter,50; pg. 480.

D.Shantkumar Lucas, Bhavaprakasha Nighantu (Indian Materia Medica), edi 2017, Chaukambha Vishvabharati, Varanasi, Haritakyadi varga, pg.68

Bapalala G Vaidya, Nighantu Adarsha, vol-2, Chaukhamba Bharati Academy, Varanasi. Reprint-2007. Ardrakadi Varga. Pg-560

D.Shantkumar Lucas, Bhavaprakasha Nighantu (Indian Materia Medica), edi 2017, Chaukambha Vishvabharati, Varanasi, Haritakyadi varga, pg.66

D.Shantkumar Lucas, Bhavaprakasha Nighantu (Indian Materia Medica), edi 2017, Chaukambha Vishvabharati, Varanasi, Haritakyadi varga. Pg-53

D.Shantkumar Lucas, Bhavaprakasha Nighantu (Indian Materia Medica), edi 2017, Chaukambha Vishvabharati, Varanasi, Haritakyadi varga. Pg-431

Shri Bapalala G Vaidya, Nighantu Adarsha, vol-2, Chaukhamba Bharati academy, Varanasi. Reprint-2007. guduchyadi varga. Pg-560

D.Shantkumar Lucas, Bhavaprakasha Nighantu (Indian Materia Medica), edi 2017, Chaukambha Vishvabharati, Varanasi, Haritakyadi varga, pg.69,45

D.Shantkumar Lucas, Bhavaprakasha Nighantu (Indian Materia Medica), edi 2017, Chaukambha Vishvabharati, Varanasi, Haritakyadi varga, pg.43.

Ghannoum, M. A., Hossain, M. A., Long, L., Mohamed, S., Reyes, G., & Mukherjee, P. K. (2004). Evaluation of Antifungal Efficacy in an Optimized Animal Model of Trichophyton mentagrophytes-Dermatophytosis. Journal of Chemotherapy, 16(2), 139–144. https://doi.org/10.1179/joc.2004.16.2.139

B.A Adeniyi et al. Antifungal Activities of an extract and cream formulation of COLA MILLENII K. SCHUM. In Dermatophyte- Infected Wistar Rats, European Journal of Pharmaceutical and Medical Research, ISSN 2394-3211, https://storage.googleapis.com/journal-uploads/ejpmr/article_issue/1554008295.pdf.