Ayurvedic Insights into Gut Microbiome Dynamics - On Trayopastambha Perspective

  • Soman C Post Graduate Scholar, Department of Kayachikitsa, Vaidyaratnam Ayurveda College, Ollur, Thrissur, Kerala, India.
  • Marikutty TC Professor and HOD, Department of Kayachikitsa, Vaidyaratnam Ayurveda College, Ollur, Thrissur, Kerala, India.
Keywords: Gut Microbiome, Trayopastamba, Ahara, Nidra, Brahmacharya

Abstract

The gut microbiome is a crucial ecosystem of microorganisms residing in the digestive tract, influencing various aspects of human health. Composed predominantly of bacteria from the Firmicutes and Bacteroidetes phyla, alongside viruses, fungi, and protozoa, it plays essential roles in digestion, nutrient synthesis, immune regulation, and protection against pathogens.[1] This complex community interacts extensively with the host, impacting metabolic processes, immune responses, and even mental health through the gut-brain axis. Maintaining a balanced gut microbiome is pivotal for efficient digestion, nutrient absorption, and overall well-being.[2] Diet profoundly shapes the gut microbiota composition; a diverse diet rich in fiber, fruits, vegetables, and fermented foods promotes microbial diversity and health, while diets high in processed foods and sugars can lead to dysbiosis, characterized by an imbalance in microbial communities.[3] Lifestyle factors such as eating junk food, sleep patterns, stress levels, less physical activity, and medication use also influence the gut microbiome. Chronic stress and inadequate sleep can disrupt microbial balance and compromise gut health. Dysbiosis has been linked to various health conditions, including gastrointestinal disorders, metabolic diseases like obesity and diabetes, autoimmune disorders, allergies, and mental health issues such as depression and anxiety.[4] Integrating  knowledge from Ayurveda, which emphasizes the importance of Trayopastamba - diet (Ahara), sleep (Nidra), and regulated lifestyle (Brahmacharya) in maintaining  gut microbiome health.[5] Ayurvedic practices advocate for a balanced diet tailored to individual Doshas, regular sleep patterns, stress management techniques, and a disciplined lifestyle, all of which contribute to maintaining a harmonious gut microbiome. By understanding and nurturing the gut microbiome through these integrated approaches, we can enhance overall health outcomes and prevent various diseases associated with microbial imbalance.

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References

Introduction to the human gut microbiota - PMC [Internet]. [cited 2024 Jul 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433529/

Surawicz CM, Stepan C. Irritable bowel syndrome: A chronic sequelae of acute gastroenteritis. Gastroenterology. 2007 Jan 1;132(1):458–60.

Barandouzi ZA, Lee J, Maas K, Starkweather AR, Cong XS. Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components. J Pers Med. 2021 Jan;11(1):35.

Gut Microbiome - an overview | ScienceDirect Topics [Internet]. [cited 2024 Jul 10]. Available from: https://www.sciencedirect.com/topics/medicine-and-dentistry/gut-microbiome

Agnivesa. Charaka samhitha. 5th ed. vaidya jadavaji trikamji, editor. Vol. sutra sthana. Varanasi: Chowkhamba Sanskrit sanstan; 2001. 300 p.

Bull MJ, Plummer NT. Part 1: The Human Gut Microbiome in Health and Disease. Integr Med Clin J. 2014 Dec;13(6):17–22.

What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases - PMC [Internet]. [cited 2024 Jul 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351938/

Lifestyle patterns influence the composition of the gut microbiome in a healthy Chinese population | Scientific Reports [Internet]. [cited 2024 Jul 10]. Available from: https://www.nature.com/articles/s41598-023-41532-4

Fekete M, Lehoczki A, Major D, Fazekas-Pongor V, Csípő T, Tarantini S, et al. Exploring the Influence of Gut–Brain Axis Modulation on Cognitive Health: A Comprehensive Review of Prebiotics, Probiotics, and Symbiotics. Nutrients. 2024 Mar 10;16(6):789.

Shivaprasad S., editor. Astanga Sangraha of Vrddha Vagbhata, Sootra Sthana. Ch. 9, Ver. 27. 4th ed. Varanasi: Choukhamba Sanskrit Series Office; 2016. 91 p.

Charaka samhitha. Reprint Edition 2011,. Vol. Vol-1, Sutrasthana 30/58,. Choukhambha Orientalia, Varanasi, 2014.;

Dwivedi, L. (ed.), Charak Samhita, Commentary of Chakrapani, Chikitsasthana, Chap 15, Verse 5, Chaukhambha Prakashana, Varanasi, 2013, 1st edn, p. 510. Charak Samhita, Commentary of Chakrapani. 2018th ed. Varanasi: Chaukhambha krishnadas academy; 510 p. (chikitsa sthanam).

Acharya, J. T. (ed.). Charak Samhita with the Ayurved Dipika Commentary. 2014th ed. Varanasi: Chaukhambha krishnadas academy; 238. (Vimanasthana,).

Acharya, J. T. (ed). Charak Samhita with the Ayurved Dipika Commentary. Varanasi: Chaukhamba Krishnadas Academy; 2010. 235 p. (Vimanasthana; vol. chapter 1,verse 21).

Acharya, J. T. (ed.). Charak Samhita with the Ayurved Dipika Commentary. 2010th ed. Varanasi: Chaukhamba Krishnadas Academy; 44–49 p. (sutra sthana).

Sharma H. Kashyapa Samhita, Khila Sthanachapter 4,verse 6. Varanasi: Chaukhambha krishnadas academy; 2013. 249 p.

Vaidya Jadavji Trikamji. susrutha samhita with Nibanda Sangraha commentary of Dalhana Acharya (Jejjata). Sharira sthana; Chapter 4; verse 33. 8th ed. Varanasi: Choukhambha Orientalia, Varanasi, 2014.;

Yadhava T editor. Charaka Samhita of Agnivesha, Sootra Sthana. Ch.11, Ver.35. 3rd edition,. Varanasi: Chaukhamba Krishnadas Academy; 2008. 74 p.

Bhaskara GG. Bagavat geeta,Vaidyakiya Subhashita Sahityam, Ch 21, Ver.7. 7th edition. 7th ed. Varanasi: Choukhamba Sanskrit samsthan; 1999. 130 p.

How your gut microbiome is linked to depression and anxiety [Internet]. [cited 2024 Jul 10]. Available from: https://www.cas.org/resources/cas-insights/how-your-gut-microbiome-linked-depression-and-anxiety

Dubik M, Pilecki B, Moeller JB. Commensal Intestinal Protozoa—Underestimated Members of the Gut Microbial Community. Biology. 2022 Dec;11(12):1742.

Microorganisms | Free Full-Text | Healthy Diet and Lifestyle Improve the Gut Microbiota and Help Combat Fungal Infection [Internet]. [cited 2024 Jul 10]. Available from: https://www.mdpi.com/2076-2607/11/6/1556

Appleton J. The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health. Integr Med Clin J. 2018 Aug;17(4):28–32.

Zhang P. Influence of Foods and Nutrition on the Gut Microbiome and Implications for Intestinal Health. Int J Mol Sci. 2022 Aug 24;23(17):9588.

Wen L, Duffy A. Factors Influencing the Gut Microbiota, Inflammation, and Type 2 Diabetes. J Nutr. 2017 Jul;147(7):1468S-1475S.

Gubert C, Kong G, Renoir T, Hannan AJ. Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases. Neurobiol Dis. 2020 Feb 1;134:104621.

Gut Microbiota Dysbiosis: Triggers, Consequences, Diagnostic and Therapeutic Options - PMC [Internet]. [cited 2024 Jul 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954387/

Dysbiosis: What It Is, Symptoms, Causes, Treatment & Diet [Internet]. [cited 2024 Jul 10]. Available from: https://my.clevelandclinic.org/health/diseases/dysbiosis

Smith RP, Easson C, Lyle SM, Kapoor R, Donnelly CP, Davidson EJ, et al. Gut microbiome diversity is associated with sleep physiology in humans. PLoS ONE. 2019 Oct 7;14(10):e0222394.

Ranade A, Gayakwad S, Chougule S, Shirolkar A, Gaidhani S, Pawar SD. Gut microbiota: metabolic programmers as a lead for deciphering Ayurvedic pharmacokinetics. Curr Sci. 2020;119(3):451–61.

Ayurveda for Obesity and Gut Health [Internet]. 2025 [cited 2024 Jul 10]. Available from: https://www.simonandschuster.com/books/Ayurveda-for-Obesity-and-Gut-Health/L-Eduardo-Cardona-Sanclemente/9781644114889

Panda A. Ayurveda Management of Liver Diseases (Yakrit Vikara). In 2020. p. 106–26.

Chauhan A, Semwal DK, Semwal RB, Joshi SK, Adhana RK, Goswami MS. Modulation of gut microbiota with Ayurveda diet and lifestyle: A review on its possible way to treat type 2 diabetes. Ayu. 2022;43(2):35–44.

Luo J, Lin X, Bordiga M, Brennan C, Xu B. Manipulating effects of fruits and vegetables on gut microbiota – a critical review. Int J Food Sci Technol. 2021 Jan 4;56.

Frontiers | Human gut microbiota in health and disease: Unveiling the relationship [Internet]. [cited 2024 Jul 10]. Available from: https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.999001/full

How gut microbes contribute to good sleep [Internet]. 2020 [cited 2024 Jul 10]. Available from: https://www.medicalnewstoday.com/articles/how-gut-microbes-contribute-to-good-sleep

Deyang T, Baig MAI, Dolkar P, Hediyal TA, Rathipriya AG, Bhaskaran M, et al. Sleep apnoea, gut dysbiosis and cognitive dysfunction. FEBS J. 2024;291(12):2519–44.

The Impact of Diet and Lifestyle on Gut Microbiota and Human Health - PMC [Internet]. [cited 2024 Jul 10]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303825/

Gut Microbiome: Understand Its Importance for Maintaining Health [Internet]. [cited 2024 Jul 10]. Available from: https://www.synlab-sd.com/en/blog/health-and-wellness-en/gut-microbiome-understand-its-importance-for-maintaining-health/

Sleep Foundation [Internet]. 2020 [cited 2024 Jul 10]. The Connection Between Diet, Exercise, and Sleep. Available from: https://www.sleepfoundation.org/physical-health/diet-exercise-sleep

CITATION
DOI: 10.21760/jaims.9.7.14
Published: 2024-09-29
How to Cite
Soman, C., & Marikutty TC. (2024). Ayurvedic Insights into Gut Microbiome Dynamics - On Trayopastambha Perspective. Journal of Ayurveda and Integrated Medical Sciences, 9(7), 109 - 118. https://doi.org/10.21760/jaims.9.7.14
Section
Review Article