The Intersection of Ayurveda and Genomics: Exploring Ayurgenomics for Personalized Health Solutions

  • Yogesh Dilip Madgulwar Assistant professor, Dept of Rasashastra & Bhaishajya Kalpana, SSVP Ayurvedic College & Research Institute, Hatta, Maharashtra, India.
  • Kalyani J. Shewalkar Assistant professor, Dept of Rasashastra & Bhaishajya Kalpana, Govt. Ayurved Mahavidyalya, Baramati, Maharashtra, India.
Keywords: Prakriti, Genome, Personalized Medicine, Tridosha

Abstract

In Ayurveda, Prakriti refers to an individual's inherent constitution or natural state, determined at conception by the unique balance of the three Doshas: Vata, Pitta, and Kapha. This constitution governs an individual's physical, mental, and emotional characteristics throughout life. Understanding one's Prakriti is key to personalized health approaches in Ayurveda, guiding diet, lifestyle, and treatment choices to maintain balance. The concept of genome can be loosely aligned with Prakriti in Ayurveda. Just as the genome contains the genetic code that dictates physical and biological traits, Prakriti determines one's physiological and psychological tendencies. Both systems emphasize the importance of individuality in health, with Ayurveda focusing on maintaining the balance of Doshas to prevent disease, much like genomics seeks to understand individual genetic variability for personalized medicine. Together, Prakriti and genome offer complementary insights into personalized health, rooted in ancient wisdom and modern science. Aim & Objective: To evaluate the Ayurvedic genetic concepts of Prakriti in relation to evidence based studies. Materials and Methods: Information extracted from various classics (Charak Samhita, Shusruta Samhita, Asthanga Sanghra, Asthanga Hridya) & Published information on recent articles in PubMed, Google scholar, Scope med & Dhara online data base were taken into consideration for review purpose. Reported data was analyzed & represented for current review. Conclusion: Ayurgenomics help to build personalised base treatment purpose for each entity of human beings in smart and efficient manner.

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References

Charak, Charak-Samhita, with Chakrapanidatta commentary, Chaukhambha Sanskrita Sansthan, Varanasi, Sharirasthana Chapter 1 verse 16.

Joshi K, Ghodke Y, Shintre P. Traditional medicine and Genomics. JAIM. 2010;1:26–32.

Sharma H. (2016). Ayurveda: Science of Life, Genetics, and Epigenetics. Ayu 37, 87–91.

Charak-Samhita, with Chakrapanidatta commentary, Chaukhambha Sanskrita Sansthan, Varanasi, Vimanasthana Chapter 8 verse 95.

Sumantran V. N., Tillu G. (2013). Insights on Personalized Medicine from Ayurveda. J. Altern. Complement. Med. 19, 370–375.

Collins FS, Fink L. The Human Genome Project. Alcohol Health Res World. 1995;19(3):190-195

Collins FS, Galas D. A new five-year plan for the U.S. human genome project. Science. 1993;262:43–46.

Gupta P. D. (2015). Pharmacogenetics, Pharmacogenomics and Ayurgenomics for Personalized Medicine: a Paradigm Shift. Indian J. Pharm. Sci. 77, 135–141

Patwardhan B. AyuGenomics–Integration for customized medicine. Indian J. Nat. Prod. Resour. 19, 16–23 (2003).

Kanchan Kararrwal, Krishan Kumar. Brief knowledge of Prakriti and its importance. J Ayurveda Integr Med Sci 2024;1:201-206.

Sharma R., Prajapati P. K. (2020). Predictive, Preventive and Personalized Medicine: Leads from Ayurvedic Concept of Prakriti (Human Constitution). Curr. Pharmacol. Rep. 6, 441–450.

Amin H., Sharma R., Vyas M., Vyas H. (2017). Genomic Counterparts to Human Constitution (Prakriti). Indian J. Anc. Med. Yoga 7, 29–37.

Singh S, Gehlot S and Agrawal NK (2019) Basis of disease manifestation: A molecular and Ayurvedic approach with an integrated concept of Ayurgenomics.

Huang, Zoufang; Chavda, Vivek P.; Bezbaruah, Rajashri; Uversky, Vladimir N.; Palagati, Sucharitha; Patel, Aayushi B.; and Chen, Zhe-Sheng, "An Ayurgenomics Approach: Prakriti-based Drug Discovery and Development for Personalized Care" (2022).

Phillips CM. Nutrigenetics and metabolic disease: current status and implications for personalised nutrition. Nutrients. 2013 Jan 10;5(1):32-57.

CITATION
DOI: 10.21760/jaims.9.10.28
Published: 2025-01-08
How to Cite
Yogesh Dilip Madgulwar, & Kalyani J. Shewalkar. (2025). The Intersection of Ayurveda and Genomics: Exploring Ayurgenomics for Personalized Health Solutions. Journal of Ayurveda and Integrated Medical Sciences, 9(10), 168 - 177. https://doi.org/10.21760/jaims.9.10.28
Section
Review Article