Therapeutic potential of Sandhaniya Maha Kashaya: A Critical Review of Ayurvedic Literature and Pharmacological Insights
Abstract
In the modern era of science and development, traditional medicines, especially those rooted in Ayurveda, hold significant therapeutic potential. Among Ayurveda's foundational texts, the Charaka Samhita emphasizes the importance of Bheshaja Chatushka, which includes chapters on therapeutic applications of various medicinal plants. In its Shadvirechanshtashreeya chapter, Acharya Charak introduces the concept of Maha Kashaya, encompassing 50 categories of 500 herbs classified based on their effects on biological systems. This study focuses on Sandhaniya Maha Kashaya, a group of ten medicinal plants renowned for their healing and tissue-binding properties. These plants aid in repairing fractures, stopping bleeding, and promoting the regeneration of muscles and bones. Their actions are attributed to their Kashaya Rasa (astringent taste) and their ability to induce tissue constriction (Sankuchana). A critical review of Ayurvedic literature, combined with the scientific classification and analysis of these plants, reveals their pharmacological potential. Key findings include detailed Ras Panchak profiles (taste, properties, potency, and post-digestive effects) of the ten plants, demonstrating their predominant Kashaya Rasa and Sheeta Virya (cooling potency), which facilitate wound healing. The discussion elaborates on the pharmacological mechanisms of prominent herbs like Madhuka, Guduchi, and Lodhra, highlighting their roles in collagen synthesis, anti-inflammatory effects, and antimicrobial properties. This exploration underscores the therapeutic relevance of Sandhaniya Maha Kashaya in promoting tissue healing, validated by its traditional applications and modern scientific insights. Such integrative studies bridge traditional knowledge and contemporary medicine, offering holistic approaches to health care.
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