A comparative clinical study to evaluate the efficacy of Amalakyavaleha and Devdali Churna in Pandu Roga w.s.r. to Iron Deficiency Anemia in Children

Abstract

Background: Pandu Roga is a condition characterizes by skin discoloration resembling Haridra or a greenish tinge, along with symptoms such as Hridayaspandanam, Roukshyam, Swedabhava, Shrama and related complications. It reflects various underlying conditions caused by a deficiency in Rakta Dhatu, such as reduced hemoglobin or RBCs. Iron Deficiency Anemia (IDA), a prevalent nutritional disorder globally, affects over 40% of children, especially in developing nations like India. IDA impairs cognitive and physical development, immunity, and overall health. While iron supplements are commonly used, their side effects often limit adherence, highlighting the need for safer, holistic treatments. Aim and Objectives: To evaluate, compare the efficacy and clinical safety of Amalakyavaleha and Devdali Churna drugs in children. Materials and Methods: A randomized, comparative clinical trial was conducted on 40 pediatric patients for 4 weeks diagnosed with IDA. The patients were divided into two groups: Group I received Amalakyavaleha, while Group II was treated with Devdali Churna. The clinical efficacy of both interventions was assessed based on subjective and objective criteria, symptomatic relief, and overall improvement in nutritional status. Results: The study revealed that both groups significantly improved clinical symptoms and hematological markers. The comparative analysis demonstrated the potential of Amalakyavaleha in addressing the underlying causes of Pandu Roga and effectively managing IDA. Conclusion: This study seeks to provide evidence for using safe and effective Ayurvedic alternatives in addressing anemia in children, offering a holistic approach that goes beyond symptom management to target the root cause.