Role of Krimi (Pathogen) in Aupasarkika Yakrit Vikara (Infective Liver diseases) - A Narrative Review
Abstract
Infective liver diseases are more than 18% of total Chronic Liver Diseases and been ranked as the fifth most common cause of death worldwide. Krimi can create systemic infection like - Jvara, Vibarnata (skin rash), Shula (Pain), Bhaktadwesa (anorexia), Krimija Pandu (Anaemia) etc. to organ specific disorders like - Krimi Danta, Krimi Karna, Asadhya Pratisyaya, Krimi Granthi, Krimija Hrudroga, Krimija Shira Roga But Krimijayakrit Vikara/Roga is not found in classical literature. A considerable number of Infectious liver disease patients came to various Ayurveda Hospital and expert Ayurveda physicians either feed up with conventional treatment or cannot bear the expenses of conventional therapy. Therefore, it is an attempt to establish the role of Krimi in Aupasarkika Yakrit Vikara through reviewing Ayurveda and modern literature with some experience-based inputs. Virus, bacteria, protozoa can be Adrisya Krimi (not visible in necked eye), Anu (minute) and Suksma and Nematodes and fungus are Drisya (Visible) Krimis. Purisaja and Raktaja Krimi can produce Krimija Yakrit Roga as near to Liver and through gut - liver axis and rich circulation of liver. Jvara (Fever), Shula (abdominal pain), Mandagni (low digestive power), Pita Netrata (Jaundice) are cardinal symptom of Krimija Yakrit Roga. In three dosas, Kapha Dosa is more aggravated in Krimija Yakrit Roga. Rakta Vaha Srotas and Purisha Vaha are mostly affected Srotas in Krimija Yakrit Roga. Sahaja Krimi or Avaikarik Krimi are said to be gut microbiota which are more than 100 trillion microorganisms in the gut show high metabolic activity and are continuously helping with the host immune system through gut-liver axis. Krimija Yakrit Roga can be a type of Yakrit Roga which clinically manifested as Yakritdalludara (Hepato megaly) and Yakrit Kshyaya (Cirrhosis of Liver). Successful diagnosis of type of Krimi can be possible though careful history and appropriate microbial and radiological studies for proper treatment of liver diseases.
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