Randomized  parallel  group  clinical  trial  to  evaluate  the efficacy of Virechana Karma and Khanda Pippali Avaleha in Amlapitta

Dr. Anshul; Dr. Alok kumar Srivastava; Dr. Pooja Rohilla

doi:10.21760/jaims.v6i01.1174

Dr. Anshul Assistant Professor, Dept. of Panchakarma, Gaur Brahman Ayurvedic College, Rohtak, Haryana,INDIA.
Dr. Alok kumar Srivastava Professor, Dept. of Panchakarma, Faculty of Ayurved, Main Campus, UAU, Dehradun, INDIA.
Dr. Pooja Rohilla Assistant Professor, Dept. of. Dravya Guna, Baba Mastnath Ayurvedic College, Rohtak, Haryana, INDIA.

DOI: https://doi.org/10.21760/jaims.v6i01.1174

Keywords: Amlapitta, Acid reflux syndrome, Khanda Pippali Avaleha, Virechana

Abstract

Introduction: Amlapitta is the result of faulty food habits and life style. Acid Reflux disease have similarity with Gastritis. Material and methods: 50 patients having Amlapitta’s symptoms for at least 4 months and on at least 5 of the 7 days prior to screening, also fulfilling the criteria were selected (Group A- 25, Group B-25) and parallel randomized in two groups. Intervention given as Virechana Karma followed by placebo capsules for 45 days in Group A and Khanda Pippali Avaleha in the dose of 10 gram/day twice in a day after meal with lukewarm water in Group B for 60 days. The primary endpoint was the 14-item self-administered questionnaire dimension score on cardinal symptoms of Amlapitta. Obtained results were analyzed statistically by independent sample “t” test for difference in group A and B. Wilcoxon sign rank was used within group comparison. Result & discussion: Both the interventions were highly significant in both the groups but when compare the mean percent change relief was found more in Group A than Group B in Daha and Avipaka. Overall, Virechana and Khand Pippali Awaleha can be better treatment modality in the management of Amlapitta.

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