The efficacy of Vidanga Triphaladi Lepa and Chandanadi Lepa in the management of Padukavisha (footwear dermatitis) - A comparative clinical trial
Abstract
Introduction: Footwear dermatitis is a CD4-T-lymphocyte mediated type-IV hypersensitivity reaction representing a distinct group among the common types of contact dermatitis reported in India with an overall prevalence of 11.7%. It is often misdiagnosed and if left untreated or mismanaged, may exacerbate causing permanent disfigurement of the skin leading to physiological, psychological and social impacts. This type of dermatitis can be correlated to Padukavisha in Ayurveda. Methods: The study was a comparative clinical trial involving 90 participants diagnosed with footwear dermatitis, randomly allocated into trial and control groups. Patch test was done for both groups to test the antigen sensitivity. Trial group received Vidangatriphaladi Lepa and control group received Chandanadi Lepa. Both groups received Dushivishari Agada as internal medicine. Clinical data was collected Before Treatment, 8th day, 15th day and on the 22nd day (follow-up). Results: Results concluded that the trial drug was more effective than the control in managing 4 of the 5 symptoms of Paduka Visha (p<0.001). The symptom Swapa had better result with the control drug. Discussion and conclusion: Vidangatriphaladi Lepa which is effective in poisoning and skin disorders, is found to be more effective than Chandanadi Lepa in managing Padukavisha.
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References
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