The scientific evaluation of Rasnadashamula Kwatha in the management of Amavata w.s.r. to Rheumatoid arthritis: A Review Article
Abstract
Background: Rheumatoid arthritis (RA) is the most common inflammatory arthritis in women and hence an important cause of potentially preventable disability. Many of the clinical features and management strategies in RA are relevant across the spectrum of inflammatory joint disease. The typical clinical phenotype of RA is a Symmetrical, deforming, small and large joint polyarthritis, often associated with systemic disturbance and extraarticular disease. The clinical course is usually life-long, with intermittent exacerbations and remissions and highly variable severity. In Ayurveda, ‘Amavata’ was mentioned for the first time by Acharya Madhavakara has a special disease entity in which both ‘Ama’ as well as ‘Vata’ play a predominant role in the pathogenesis of this disease. Aim: The Article is written with the aim to analyze the of mode of action of the ingredients of Rasnadashamula Kwatha and explore its importance in relieving the symptoms of Amavata w.s.r. to Rheumatoid arthritis. Methodology: Rasnadashamula Kwatha is described in Amavata Rogadhikara in Chakradatta . Various peer reviewed articles, Ayurvedic classical textbooks, Modern Rheumatological textbooks as well as the online databases were analyzed under the relevant key words in understanding the importance of the above-mentioned formulation in treating the symptoms of Amavata w.s.r. to Rheumatoid arthritis. Conclusion: It can be concluded through literary review that Rasnadashamula Kwatha is efficient in relieving the symptoms of Amavata but to establish the final conclusion clinical trial of this drug should be conducted so that this drug can be used for therapeutic purposes in general patients of Amavata.
Downloads
References
Yash Pal Munjal (Ed) (2015), API Textbook of Medicine, volume 2 10th edition page no 2492 2493
Harsh Mohan, Textbook of Pathology 5th edition page number 3421-3427
Yash Pal Munjal (Ed) (2015), API Textbook of Medicine, volume 2 10th edition page no 2492 2493
Dr. Bramhananda Tripathi, Madhava Nidana (Roga Vinishchaya) of Sri Madhavakara with the Sanskrit commentary Madhukosha vol 1, Chaukamba Surbharti prakashan Varanasi pg no 571
Chakradatta Pandit Sadananda Sharma, Meharachand Lachamandas Publications march 2000 page no 188-189
Yash Pal Munjal (Ed) (2015), API Textbook of Medicine, volume 2 10th edition page no 2492 2493
Dennis. L.Kasper, MD, Anthony S. Fauci, MD, Sthephen L. Hauser, MD, J.Larry Jameson,MD,PhD, Dan L.Longo,MD, Joseph Loscalzo, MD,Phd(Ed) Harrison’s Principles of Internal Medicine 19th edition page no 2136-2137
Dr. Bramhananda Tripathi, Madhava Nidana (Roga Vinishchaya) of Sri Madhavakara with the Sanskrit commentary Madhukosha vol 1, Chaukamba Surbharti prakashan Varanasi pg no 578
Rasnadashamula Kwatha Chakradatta pandit Sadananda sharma, Meharachand lachamandas publications march 2000pg no 188-189
A textbook of Bhaishajya Rathnavali, Ravindra Angadi, Chaukambha Surbharti Publications 2012, Page number 20-25
Padmashri Prof Krishnachandra Chunekar Bhavaprakasha Nighantu Reprint 2020 chaukambha bharti academy
Parekar RR, Bolegave SS, Marathe PA, Rege NN. Experimental evaluation of analgesic, anti-inflammatory and anti-platelet potential of Dashamoola. Journal of Ayurveda and integrative medicine. 2015 Jan;6(1):11.
Mali PY. Pharmacological potentials of Premna integrifolia L. Ancient Science of Life. 2016 Jan;35(3):132
Dhama K, Sachan S, Khandia R, Munjal A, MN Iqbal H, K Latheef S, Karthik K, A Samad H, Tiwari R, Dadar M. Medicinal and beneficial health applications of Tinospora cordifolia (Guduchi): a miraculous herb countering various diseases/disorders and its Immunomodulatory effects. Recent Patents on Endocrine, Metabolic & Immune Drug Discovery. 2016 Aug 1;10(2):96-111.
Khan Marwat S, Khan EA, Baloch MS, Sadiq M, Ullah I, Javaria S, Shaheen S. Ricinus cmmunis: Ethnomedicinal uses and pharmacological activities. Pakistan journal of pharmaceutical sciences. 2017 Sep 1;30(5).
Hussain H, Al‐Harrasi A, Abbas G, Rehman NU, Mabood F, Ahmed I, Saleem M, van Ree T, Green IR, Anwar S, Badshah A. The genus Pluchea: Phytochemistry, traditional uses, and biological activities. Chemistry & biodiversity. 2013 Nov;10(11):1944-71.
Ali BH, Blunden G, Tanira MO, Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food and chemical Toxicology. 2008 Feb 1;46(2):409-20.
Galani VJ, Patel BG, Patel NB. Argyreia speciosa (Linn. f.) sweet: A comprehensive review. Pharmacognosy Reviews. 2010 Jul;4(8):172.
Allaire SL, Prashker M, Meenan R. The costs of rheumatoid arthritis. Pharmoeconomics 1994; 6: 513– 22.
Majithia, V., & Geraci, S. A. (2007). Rheumatoid arthritis: diagnosis and management. The American journal of medicine, 120(11), 936-939.
Pinals RS, Masi AT, Larsen RA, and the Subcommittee for Criteria of Remission in Rheumatoid Arthritis of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for clinical remission in rheumatoid arthritis. Arthritis Rheum 1981; 24: 1308– 15.
Charaka Samhita, Vimana Sthana 2nd chapter chakrapani data, Ayurveda deepika page number 355-356
Chakradatta Pandit Sadananda Sharma, Meharachand Lachamandas Publications march 2000pg no 188-189
Charaka Samhitha Sutrasthana 26th chapter Chakrapani dutta, Ayurveda deepika page number 234-239
Charaka Samhitha Sutrasthana 26th chapter Chakrapani dutta, Ayurveda deepika page number 345-349
Journal of Ayurveda and Integrated Medical Sciences (JAIMS) retains the copyright of the contents of this journal but grant the readers the right to use the contents with terms and conditions under a creative common attribution licenses 4 of Attribution, Share Alike and Non-commercial type (CC BY-NC-SA) that allows copy, distribute, display, and perform the work and make derivative works based on it only for non-commercial purposes.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.