Retrospective evaluation of the efficacy, safety and satisfaction of AyurCoro3 : A patient-reported outcomes study

  • Ajay Prabhakar Sankhe Director, Bhaktivedanta Hospital and Research Institute, Thane, Maharashtra, India.
  • Nanasaheb Somnath Memane Head, Ayurveda Dept., Bhaktivedanta Hospital and Research Institute, Thane, Maharashtra, India.
  • Vijaykumar P. Gawali Head, Clinical Research, Bhaktivedanta Hospital and Research Institute, Thane, Maharashtra, India.
  • Sonal Nanasaheb Memane Consultant Ayurveda, Bhaktivedanta Hospital and Research Institute, Thane, Maharashtra, India.
  • Mayur Nimba Bagul Research Coordinator, Bhaktivedanta Hospital and Research Institute, Thane, Maharashtra, India.
  • Ganesh Ramakrishnan Professor, Computer Science and Engineering, Indian Institute of technology, Mumbai, Maharashtra, India.
Keywords: Coronavirus infections, COVID-19, Ayurveda, Complementary and Alternative Medicine, prophylaxis.

Abstract

Background: At the backdrop of absence of any approved treatment for COVID-19 infections, Ayurvedic treatment can be explored for its potential. AyurCoro-3 is a combination of Gomutra (bos indicus urine), hot water, turmeric, Turati churna (potassium Alum), candy sugar (khadisakhar), Bos indicus milk with two teaspoons of Go Ghrut (Ghee) with antimicrobial and immunomodulatory properties. The present study evaluated the responses from individuals who consumed Ayurcoro-3. Methods: A retrospective observational study was carried out based on the participants who consumed Ayurcoro-3. Participants were asked about their reasons for taking the drug, whether as prophylaxis/treatment, duration of symptoms following the drug intake compared to baseline, their satisfaction with Ayurcoro-3, and adverse events. Results: Two thousand participants were recruited, and majority consumed Ayurcoro-3 as a prophylactic drug (1285, 64.25 %). Amongst those who were symptomatic, 317 had cough and 328 had fever, and 299 had positive RT-PCR test. The mean (SD) duration of symptoms were significantly shorter following the intake of Aurcoro-3 as follows: cough [before: 4.64 (3.26), after: 2.26 (1.34) days; p < 0.05], fever [before: 4.16(2.40), after: 2.15(1.34) days; p < 0.05], breathlessness [before: 5.56 (2.66), after: 2.30 (1.19) days; p < 0.05], and weakness [before: 5.69 (3.08), after: 2.36 (1.13) days; p < 0.05]. Majority of the participants stated that they were very satisfied with Ayurcoro-3. None of the participants reported any serious adverse reaction and only few adverse events were reported. Conclusion: We found that Ayurcoro-3 to be highly effective and safe in preventing/treating COVID-19 related symptoms and the patients are highly satisfied with the response.

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References

Triggle CR, Bansal D, Farag EABA, Ding H, Sultan AA. COVID-19: Learning from lessons to guide treatment and prevention interventions. mSphere. 2020; 5(3): e00317-20.

Paudyal V, Sun S, Hussain R, Abutaleb MH, Hedima EW. Complementary and alternative medicines use in COVID-19: A global perspective on practice, policy and research. Res Social Adm Pharm. 2021; S1551-7411(21)00170-4.

Shafiq N, Gupta M, Kumari S, Pandhi P. Prevalence and pattern of use of complementary and alternative medicine (CAM) in hypertensive patients of a tertiary care center in India. Int J Clin Pharmacol Ther. 2003; 41(7): 294-8.

Wode K, Henriksson R, Sharp L. et al. Cancer patients’ use of complementary and alternative medicine in Sweden: a cross-sectional study. BMC Complement Altern Med 2019; 19: 62.

Charan J, Bhardwaj P, Dutta S, et al. Use of Complementary and Alternative Medicine (CAM) and home remedies by COVID-19 Patients: A telephonic survey. Ind J Clin Biochem 2011; 36: 108–111.

Kaushik R, Jain J and Rai P: Therapeutic Potentials of Cow Derived Products- A Review. Int J Pharm Sci Res 2016; 7(4): 1383-90.

Kumar A, Naik SN. Ghee: Its properties, importance and health benefits. Lipid Universe 2018; 6: 1-9.

Minochecherhomji FP. Bio-enhancing properties of cow urine – a review. Int. J. Innov. Res. Sci., Eng., Techn. 2016; 5: 16283-16287.

Ayurcoro-3. Available at: https://ayurcoro3.com/ (Accessed on 8 July 2021).

Ashwagandha against coronavirus: Researchers from IIT-Delhi and Japan's AIST make an interesting discovery about the Ayurvedic drug. Available at: https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/coronavirus-treatment-ayurvedic-drug-covid-19-cure-ashwagandha-against-coronavirus-researchers-from-iit-delhi-and-japans-aist-make-an-interesting-discovery-about-the-ayurvedic-drug/photostory/75864118.cms (Accessed on 9 July 2021).

Gautam S, Gautam A, Chhetri S, Bhattarai U. Immunity Against COVID-19: Potential Role of Ayush Kwath. J Ayurveda Integr Med. 2020;10.1016/j.jaim.2020.08.003.

Charan J, Kaur R, Bhardwaj P, Kanchan T, Mitra P, Yadav D, Sharma P, Misra S. Snapshot of COVID-19 Related Clinical Trials in India. Indian J Clin Biochem. 2020; 35(4): 1-5.

CITATION
DOI: 10.21760/jaims.v6i4.1385
Published: 2021-09-15
How to Cite
Ajay Prabhakar Sankhe, Nanasaheb Somnath Memane, Vijaykumar P. Gawali, Sonal Nanasaheb Memane, Mayur Nimba Bagul, & Ganesh Ramakrishnan. (2021). Retrospective evaluation of the efficacy, safety and satisfaction of AyurCoro3 : A patient-reported outcomes study. Journal of Ayurveda and Integrated Medical Sciences, 6(4), 08 - 12. https://doi.org/10.21760/jaims.v6i4.1385
Section
Original Article

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