A clinical study to evaluate the combined effect of Kalyanaka Ghrita and S-GABA Churna (an indigenous formulation) on psychological symptoms in Perimenopausal Syndrome

Abstract

Introduction: Perimenopause is the physiological transitional phase, where the estrogen level decreases due to depletion in ovarian follicular activity. Even though it is a physiological condition decreased estrogen secretion in the circulating system result in group of symptoms termed as Perimenopausal syndrome, consisting of psychological, vasomotor, somatic and uro-genital symptoms. The psychological symptoms are anxiety, depression, irritability, crying spells, lack of concentration, loss of memory and sleep disturbances which needs to be handled with specific intervention. Materials & Methods: It was single group study, with pre-post test design.  Study included 32 subjects between the age group 40–55-year females. Kalyanaka Ghrita was used for Nasya Karma, S-GABA Churna as Shamanaoushadhi. Result: The results obtained after completion of intervention showed statistically highly significant with p value 0.001. Conclusion: The psychological symptoms in perimenopausal syndrome was effectively managed with Kalyanaka Ghrita Nasya Karma and S-GABA Churna as Shamanoushadhi.