Experimental evaluation of antihyperglycemic activity of Vangasindhoora against streptozotocin (stz) induced diabetes in wistar albino rats

Abstract

Rasasastra refers to the science of making metals and minerals assimilable for the body so they can be used as medicines and give effective result even in smaller dose. Kupipakva Rasayana bears a unique place in Rasasastra as it has quicker action and synergistic effect in body at very low dose. Vangasindhoora is a Kupipakva Rasayana preparation mentioned in Rasendra Sambhava and is indicated in all Prameha. Vangasindhoora contains Vanga, Parada, Gandhaka and Navasara as ingredients. Diabetes is caused due to absolute or relative deficiency of insulin. Today’s lifestyle has been changed and sharp increase in the incidence and prevalance of diabetes mellitus has been perceived. In the present study experimental evaluation of antihyperglycemic effect of Vangasindhoora has been dealt and the result were assessed using one-way Anova followed by Dunnet’s multiple comparison t-test using graph pad instant software. Result shows that vangasindhoora has antihyperglycemic effect.