Randomized open label comparative clinical study on the efficacy of combination of Chandana Churna and Shatapushpa Taila Nasya with Tranexamic Acid in Rakta Pradara (DUB)

Abstract

Incidence of Rakta Pradara (DUB) is on rise due to life style changes. Rough estimate suggests that 10 to 13% of all gynaecological outpatients are for Rakta Pradara(DUB).^[1] Dysfunctional uterine bleeding is a state of abnormal uterine bleeding without any clinically detectable organic, systemic and iatrogenic cause.^[2] As per Nidhana of Rakta Pradara the aggravated Vata withholds Rakta vitiated due to various reasons mentioned in Nidana of Rakta Pradara increases its amount reaching Rajovaha Srotas which further increases the rajas, the Srotas involved is Artavavaha Srotas, here Artava Vaha Srotas taken as whole female genital organs along with functional axis i.e., H-P-O axis. Altered H-P-O axis and GNRH regulation causes Rakta Pradara (DUB). So, in this study to treat Rakta Pradara through nearest route Nasya Karma with Shatapushpa Taila is selected along with oral Chandana Choorna along with Madhu and Sharkara.