An open label, single arm prospective clinical study on the effectiveness of Pugaarimeda Kashaya in Madhumeha (Diabetes Mellitus Type 2)
Abstract
Background: Diabetes mellitus (DM) is one of the most common non-communicable diseases globally. It is characterized by multiple metabolic disorders that results in hyperglycemia. Diabetes mellitus type-2 (DM2) is the most common type accounting almost 90% of cases of DM. Madhumeha on the basis of similar etiology, signs and symptoms can be co-related with Diabetes mellitus type-2. It is also described by the term Kshoudrameha or Ojomeha. Pugaarimeda Kashaya with Madhu as Anupana is mentioned in Brihat Nighantu Ratnakara in the management of Madhumeha. Objective: To clinically evaluate the effectiveness of Pugaarimeda Kashaya in Madhumeha (Diabetes mellitus type-2). Materials and Methods: Among 31 registered subjects, 28 of them completed the course of treatment. They were administered with Pugaarimeda Kashaya orally 100ml per day (50ml twice daily before food) with Anupana of Madhu 5ml for a period of 30 days. Blood and urine glucose test was done on 1st, 31st day of study initiation. For Statistical analysis subjective parameters were assessed by Cochran’s Q test followed by McNemar test and objective parameters were assessed by Paired sample T Test. Results: There was statistically significant improvement observed in the signs and symptoms of Madhumeha with blood and urine glucose levels. (p<0.05) Conclusion: Pugaarimeda Kashaya was found effective in the management of Madhumeha.
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