Use of Pipal tree (Ficus religiosa) extract in Lumbar Disc Lesion - Induced Neuropathy

Abstract

Incidences of neuropathic pain can occur following a lesion in or a disease of the somatosensory nervous system leading to problems of poor physical, cognitive, and psychosocial health. Roots of neuropathic pain can be in a number of diseases like diabetes mellitus, herpes zoster, cancer, spinal disorders, and human immunodeficiency virus infection as well as in some clinical interventions like chemotherapy and surgery, and in physical injuries like accidents and related trauma resulting in spinal cord injuries. Therefore, regimen of treatments varies according to the etiology and chronicity. Various types of treatments and medications are prevalently being used to alleviate neuropathic pain. These medicines have varying analgesic effects with frequent side effects including dependency issues. The idea of using herbal extract of Pipal tree (Ficus religiosa) for neuropathic pain was developed after extensive study of Ayurveda literature, discussion with Ayurveda experts while keeping in mind the descriptions about it in Indian ancient literature like Puranas and Shastras. So far specific chemicals extracted from Pipal are not scientifically studied for their effects on neurological conditions. However, recently it was reported that its biochemical contents have some neurotrophic effects. In order to assess the neurotrophic effects of Pipal extract and its beneficial effects in chronic neuropathic pain of lower limbs induced by lumbar disc lesions, we carried out a study. Our findings demonstrate that the herbal extract helped the patients without inciting any unwanted side effects.